A5080084695- COVID-19 Clinical Research Studies
- Cancer, Hypoxia, and Metabolism
- Wound Healing and Treatments
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- SARS-CoV-2 detection and testing
- Periodontal Regeneration and Treatments
- Colorectal and Anal Carcinomas
- Fibroblast Growth Factor Research
- Cytomegalovirus and herpesvirus research
- Clostridium difficile and Clostridium perfringens research
- Toxoplasma gondii Research Studies
- Computational Drug Discovery Methods
- Electrospun Nanofibers in Biomedical Applications
- Fetal and Pediatric Neurological Disorders
- Gut microbiota and health
- Cardiovascular Function and Risk Factors
- Pancreatitis Pathology and Treatment
- Pharmacological Effects of Natural Compounds
- Acute Kidney Injury Research
- Pressure Ulcer Prevention and Management
- Immune cells in cancer
- Angiogenesis and VEGF in Cancer
- interferon and immune responses
- Cholangiocarcinoma and Gallbladder Cancer Studies
Second Xiangya Hospital of Central South University
2025
Central South University
2025
Wenzhou Medical University
2020-2023
First Affiliated Hospital of Wenzhou Medical University
2021-2022
Shaoxing People's Hospital
2022
China Medical University
2022
Zhejiang Taizhou Hospital
2020
RT-PCR is the primary method to diagnose COVID-19 and also used monitor disease course. This approach, however, suffers from false negatives due RNA instability poses a high risk medical practitioners. Here, we investigated potential of using serum proteomics predict viral nucleic acid positivity during COVID-19. We analyzed proteome 275 inactivated samples 54 out 144 patients shortlisted 42 regulated proteins in severe group 12 non-severe group. Using these several key clinical indexes,...
The role of inulin in alleviating obesity-related disorders has been documented; yet, its underlying mechanisms still need to be further investigated. This study attempted elucidate the causative link between gut microbiota and beneficial effect on via transferring fecal from inulin-dosed mice high-fat diet (HFD)-induced obese recipient mice. results show that supplementation can decrease body weight, fat accumulation, systemic inflammation also enhance glucose metabolism HFD-induced...
As conventional treatments for diabetic wounds often fail to achieve rapid satisfactory healing, the development of effective strategies accelerate wound repair is highly demanded. Herein, fibroblast growth factor 21 (FGF21) and metformin co-loaded multifunctional polyvinyl alcohol (PVA) hydrogel were fabricated improved healing. The in vitro results proved that was adhesive injectable, it could particularly scavenge reactive oxygen species (ROSs), while vivo data demonstrated promote...
Glioma is the most common brain tumor and characterized by high mortality rates, recurrence short survival time. Migration invasion are basic features of gliomas. Thus, inhibition migration may be beneficial for treatment patients with glioma. Due to its antitumor activity chemical reactivity, fraxetin has attracted extensive interest been proven an effective agent in various cancer types. However, currently, potential effects on glioma have not investigated. Here, we demonstrate that can...
Abstract Background: Serum Amyloid A (SAA) is an acute-phase reactant downstream of the pro-inflammatory cytokines released during virus infection. However, role this inflammatory marker in SARA-CoV-2 infection yet to be elucidated. Here, we explored potential use SAA serum as a biomarker for monitoring clinical course COVID-19 patients.Methods: The subjects included 95 patients discharged from hospital with acute and / or convalescent phases data, among them 69 had paired data. Mann-Whitney...
Background: Since December 8, 2019, China is experiencing an outbreak of pneumonia caused by 2019 novel coronavirus (COVID-19). The purpose this study to get a better understanding the epidemiology and clinical characteristics disease in non-COVID-19-exporting city, Zhejiang. Methods: In study, we collected information all confirmed cases COVID-19 Zhejiang province from Jan 1 Feb 10, 2020. We analyzed epidemiological statistical methods, correlation between factors infection was compared...
This study aims to compare the incidence and clinical survival characteristics of adenosquamous carcinoma pancreas (ASCP) adenomatous (ACP), analyze factors ASCP construct a prognostic model.Patients diagnosed with pancreatic cancer from 2000 2018 are selected SEER database. ACP compared in terms epidemiology, prognosis. Cases matched 1:2 ratio, analysis is performed. The Cox proportional hazard model used determine covariates related overall (OS), an prognosis nomogram constructed verified...
Toxoplasma gondii infection is not uncommon in daily life; primary with (T. gondii) acquired during gestation may lead to a series of fetal complications. Prenatal ultrasound and postpartum neonatal T. encephalitis have been reported previously, but MRI findings are quite rare. It important identify the severity cerebral damage assess prognosis.The purpose this report emphasize that can provide more excellent anatomic information on abnormalities parenchyma than ultrasound, which helpful for...
The diagnosis and disease course monitoring of COVID-19 are mainly based on RT-PCR analysis RNAs extracted from pharyngeal or nasopharyngeal swabs with potential live virus, posing a high risk to medical practitioners. Here, we investigated the feasibility applying serum proteomics classify patients in nucleic acid positive (NCP) negative (NCN) stages. We analyzed proteome 320 inactivated samples 144 patients, 45 controls shortlisted 42 regulated proteins severe group 12 non-severe group....