A5064635725- Electrospun Nanofibers in Biomedical Applications
- Silk-based biomaterials and applications
- Wound Healing and Treatments
- Surgical Sutures and Adhesives
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Diet, Metabolism, and Disease
- Angiogenesis and VEGF in Cancer
- Peripheral Artery Disease Management
- Berberine and alkaloids research
- Tryptophan and brain disorders
- Diabetes and associated disorders
- Bioactive natural compounds
- Tissue Engineering and Regenerative Medicine
- Diabetic Foot Ulcer Assessment and Management
- Burn Injury Management and Outcomes
- Cardiac Fibrosis and Remodeling
- Polymer Surface Interaction Studies
- Hemostasis and retained surgical items
- Synthesis of Indole Derivatives
- Curcumin's Biomedical Applications
- Obesity, Physical Activity, Diet
- Ginseng Biological Effects and Applications
- Natural product bioactivities and synthesis
- Dermatologic Treatments and Research
Second Hospital of Anhui Medical University
2024
Anhui Medical University
2024
Wenzhou Medical University
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Fuzhou University
2022-2024
Chengdu University of Traditional Chinese Medicine
2023
Severe burn wounds usually destroy key cells' functions of the skin resulting in delayed re-epithelization and wound regeneration. Promoting activities is crucial for repair. It well known that keratinocyte growth factor-2 (KGF-2) participates proliferation morphogenesis epithelial cells while acidic fibroblast factor (aFGF) a mediator endothelial cell differentiation. However, thick eschar harsh environment often decrease delivery efficiency (FGF) to site. Therefore, herein novel...
Rapid and strong adhesion of hydrogel adhesives is required for instant wound closure hemostasis. However, in situ formation sufficient at target tissue sites biological environments are severely compromised by the presence blood body fluids. In this work, an underwater adhesive (named SHCa) fabricated with rapid gelation, enhanced mechanical toughness, robust adhesion. The SHCa can undergo UV irradiation-induced gelation under water within 5 s adhere firmly to surfaces 6 months. synergistic...
Estimation of global diabetes burden in adolescents and young adults (10–24 years) from 1990 to 2021. Data were extracted the 2021 Global Burden Disease Study. Joinpoint regression analysis was employed examine trends over past 30 years, frontier identified regions with potential for improvement, slope index inequality relative concentration used assess health inequalities. From 2021, age-standardized prevalence rates (ASPR) disability-adjusted life years (ASDR) increased globally, while...
Powder-based hemostatic technology has offered unprecedented opportunities in surgical sealing and repair of irregularly shaped noncompressible wounds. Despite their routine use, existing clinical powders are challenged either by poor mechanical properties or inadequate adhesion to bleeding tissues biological environments. Here, inspired the mussel foot proteins' fusion assembly strategy, a novel silk fibroin-based powder (named as SF/PEG/TA) with instant robust performance is developed....
Depressive disorders, as a mental disorder, are prevalent among women, particularly women of childbearing age (WCBA). However, comprehensive epidemiological studies on this population appear to be limited globally. To investigate the longitudinal epidemiology depressive disorders aged 15-49 years worldwide. Estimates annual incidence, prevalence, and disability-adjusted life (DALYs) for seven groups (15-49 years) were extracted from 2021 Global Burden Disease Study, including 95% uncertainty...
As conventional treatments for diabetic wounds often fail to achieve rapid satisfactory healing, the development of effective strategies accelerate wound repair is highly demanded. Herein, fibroblast growth factor 21 (FGF21) and metformin co-loaded multifunctional polyvinyl alcohol (PVA) hydrogel were fabricated improved healing. The in vitro results proved that was adhesive injectable, it could particularly scavenge reactive oxygen species (ROSs), while vivo data demonstrated promote...
The management of infected wounds is still an intractable challenge in clinic. Development antibacterial wound dressing great practical significance for management. Herein, a natural-derived drug, tannic acid (TA), was incorporated into the electrospun polyvinyl alcohol (PVA) fiber (TA/PVA fiber, 952 ± 40 nm diameter). TA worked as cross-linker via hydrogen bonding with PVA to improve physicochemical properties and reach sustained drug release (88% at 48 h). Improved mechanical property...