- Blood Coagulation and Thrombosis Mechanisms
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Lysosomal Storage Disorders Research
- Folate and B Vitamins Research
- Hemophilia Treatment and Research
- Sirtuins and Resveratrol in Medicine
- Pregnancy and preeclampsia studies
- Glycosylation and Glycoproteins Research
- Cellular transport and secretion
- Glutathione Transferases and Polymorphisms
- Sperm and Testicular Function
- Studies on Chitinases and Chitosanases
- Venous Thromboembolism Diagnosis and Management
- Biochemical and Molecular Research
- Renin-Angiotensin System Studies
- Pharmacological Effects and Toxicity Studies
- Birth, Development, and Health
- Vitamin D Research Studies
- Metabolism and Genetic Disorders
- Biochemical effects in animals
- Protease and Inhibitor Mechanisms
- Blood Pressure and Hypertension Studies
- Acute Lymphoblastic Leukemia research
- Inflammatory Biomarkers in Disease Prognosis
Kermanshah University of Medical Sciences
2012-2023
Tarbiat Modares University
2016
Shahid Sadoughi University of Medical Sciences and Health Services
2016
Background: The aim of the present study was to investigate association between angiotensin converting enzyme (ACE) insertion/deletion (I/D) and II type-1 receptor (AT1R) A1166C polymorphisms with risk preeclampsia lipid peroxidation in preeclamptic women from Western Iran. Methods: One hundred ninety-eight (128 mild 70 severe forms) 100 age- parity-matched controls were enrolled this case-control study. Results: presence D allele ACE associated a 1.8-fold increased ( p=0.002) total...
The aim of present study was to investigate the prevalence factor V Leiden (FVL) c.1691G>A, prothrombin g.20210G>A and methylenetetrahydrofolate reductase (MTHFR) c.677C>T in deep vein thrombosis (DVT) patients their possible association with DVT western Iran. Eighty mean age 42.07 ± 13.0 years including 44 women 36 men 100 sex-matched healthy individuals 37.63 13.3 from Kermanshah Province Iran ethnic background Kurd were studied for FVL MTHFR by PCR-restriction fragment length polymorphism...
There are controversial results related to the contribution of factor V Leiden G1691A, prothrombin gene G20210A and methylentetrahydrofolate reductase (MTHFR) C677T mutations in development coronary artery disease (CAD) their association with diabetes. To assess distribution these thrombophilic CAD patients without type 2 diabetes mellitus (T2DM), we studied 117 [65 (CAD/T2DM) 52 (CAD/ND)] 59 age-matched sex-matched healthy individuals from population western Iran. Genotyping was done by...
Human brucellosis is a multisystem disease with wide range of clinical signs which often leads to misdiagnosis and treatment delay. Early diagnosis this can prevent the serious complications mismanagements. This study aimed evaluate hematological parameters predictive value for brucellosis.
The present study aimed at investigating the prevalence of factor V Leiden G1691A, prothrombin G20210A, and MTHFR C677T in cerebral venous sinus thrombosis (CVST) patients their possible association with CVST Western Iran. A total 24 mean age 37.1 +/- 11.7 years 100 sex- age-matched healthy individuals from Kermanshah Province Iran ethnic background Kurd were studied for G20210A by PCR-RFLP method using Mnl I, Hind III, Hinf I restriction enzymes, respectively. Prevalence was 16.7% 2%...
Reactive oxygen species (ROS) play a crucial role in etiology of DNA fragmentation and lipid peroxidation sperm, leading to infertility men. The silent information regulators SIRT1 SIRT3 are members the sirtuins protein family known be involved cancer genetics, aging oxidative stress responses. aim ofthis study is determine correlation between with antioxidants, biomarkers, semen asthenoteratozoospermic normozoospermic men.In this case-control study, after spermogram analysis specimens were...
Objectives: Temporomandibular disorders (TMD) are characterized by pain or discomfort in the temporomandibular joint, periauricular region, masticatory muscles, and neck on one both sides. It may also be associated with joint sounds, restricted mandibular movements deviation. Oxidative agents have a deleterious role pathogenesis of diseases, oxidative stress can lead to TMD. The aim this study was assess biomarkers saliva TMD patients healthy controls. Materials Methods: This case-control...
Abstract Caveolin‐1(cav‐1) is overexpressed in prostate cancer (PC) and associated with progression of the disease. We investigated effects CAV1‐T29107A endothelial nitric oxide synthase (eNOS) G894T polymorphisms on serum levels testosterone, NO prostate‐specific antigen (PSA) patients PC. genotyped cav‐1 eNOS genes 112 PC 150 healthy controls by PCR‐RFLP. Serum were measured using spectrophotometry, testosterone PSA ELISA. The frequencies CAV1 genotypes A/T vs. A/A according to dominant...