A5022356621- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Impact and Responses
- HIV Research and Treatment
- Adolescent and Pediatric Healthcare
- Tuberculosis Research and Epidemiology
- Innovations in Medical Education
- Child and Adolescent Health
- Food Security and Health in Diverse Populations
- Interprofessional Education and Collaboration
- Intimate Partner and Family Violence
- Global Maternal and Child Health
Desmond Tutu HIV Foundation
2017-2024
Stellenbosch University
2018-2024
Health workers in 21 government health facilities Zambia and South Africa linked spatial organisation of HIV services material items signifying HIV-status (for example, coloured client cards) to the risk People Living with (PLHIV) 'being seen' or identified by others. Demarcated services, distinctive flow associated-items were considered especially distinguishing. Strategies circumvent any resulting stigma mostly involved PLHIV avoiding and/or reducing contact visibility through alterations...
Abstract Introduction HPTN 071 (PopART) is a three‐arm community randomized trial in Zambia and South Africa evaluating the impact of combination HIV prevention package, including universal test treat (UTT), on incidence. This nested study examined factors associated with timely linkage‐to‐care ART initiation (TLA) (i.e. within six‐months referral) context UTT intervention communities trial. Methods Of 7572 individuals identified as persons living (PLWH) (and not antiretroviral treatment...
The impact of HIV stigma on viral suppression among people living with (PLHIV) is not well characterized.Twenty-one communities in Zambia and South Africa, nested within the HPTN 071 (PopART) trial.We analyzed data (<400 copies RNA/mL) 5662 laboratory-confirmed PLHIV aged 18-44 years who were randomly sampled PopART trial population cohort 24 months after enrolment (PC24). We collected experiences internalization from those self-reported their status (n = 3963/5662) perceptions a 20% random...
Abstract Despite continued development of effective HIV treatment, expanded access to care and advances in prevention modalities, HIV‐related stigma persists. We examine how, the context a universal HIV‐testing treatment trial South Africa Zambia, increased availability services influenced conceptualisations HIV. Using qualitative data, we explore people’s stigma‐related experiences living ‘intervention’ ‘control’ study communities. conducted exploratory data analysis from cohort 150...
To assess the impact of a combination HIV prevention intervention including universal testing and treatment (UTT) on stigma among people living with HIV, community members health workers not HIV.This study was nested in HPTN 071 (PopART) trial, three-arm cluster randomised trial conducted between 2013 2018 21 urban/peri-urban communities (12 Zambia nine South Africa).Using an adjusted two-stage cluster-level analysis, controlling for baseline imbalances, we compared multiple domains arms at...
The global expansion of HIV testing, prevention and treatment services is necessary to achieve epidemic control promote individual population health benefits for people living with (PLHIV) in sub-Saharan Africa. Community-based workers (CHWs) could play a key role supporting implementation at scale. In the HPTN 071 (PopART) trial Zambia South Africa, cadre 737 study-specific CHWs, working closely government-employed CHW, were deployed deliver 'universal' door-to-door package, including an...
To determine the impact of a community-wide combination HIV-prevention package (PopART Intervention) that includes universal testing and treatment (UTT) on knowledge HIV status, among adolescents aged 15--19 years.
Abstract Introduction To investigate the association between individual and community‐level measures of HIV stigma incidence within 21 communities participating in HPTN (071) PopART trial Zambia South Africa. Methods Secondary analysis data from a population‐based cohort followed‐up over 36 months 2013 2018. The outcome was rate incident infection among individuals who were negative at entry. Individual‐level exposures, measured random sample all participants, were: (1) perception community,...
Abstract Objective The HPTN 071 (Pop ART ) trial is examining the impact of a package including universal testing and treatment on community‐level HIV incidence in Zambia South Africa. We conducted nested case–control study to examine factors associated with acceptance home‐based counselling ( HB ‐ HTC delivered by community ‐care providers CH iPs) Pop intervention communities. Methods Of 295 447 individuals who were offered testing, random samples declined (cases) accepted (controls),...
The paediatric tuberculosis (TB) prevention and treatment landscape is moving into a new exciting era, with knowledge from clinical trials offering real benefit to children. Community engagement key optimising the success of these trials. However, profile, epidemiology social perceptions for multidrug-resistant TB (MDR-TB) complicate operationalisation this community engagement. We reflect on diversity recent experiences attempting implement type research around it. describe four...
Introduction The HPTN071 (PopART) for Youth (P-ART-Y) study evaluated the acceptability and uptake of a community-level combination HIV prevention package including universal testing treatment (UTT) among young people in Zambia South Africa. We determined whether four-question primary care level screening tool, validated use clinical settings, could enhance community (door-to-door) identification undiagnosed HIV-positive younger adolescents (aged 10–14) who are frequently left out...
Background: The HPTN 071 (PopART) trial implemented universal test and treat (UTT) in three clinics the Western Cape, South Africa at a time when antiretroviral treatment (ART) was only offered by CD4 threshold World Health Organization clinical staging. This required concomitant shift way health workers communicated ART initiation messages. We provide insight into front-line communication pre-national policy shift.Method: design of this study exploratory with case descriptive analysis...
The HPTN 071(PopART) study was a community-randomised trial in Zambia and South Africa, examining the impact of combination-prevention including universal testing treatment (UTT), on HIV-incidence. This sub-study evaluated factors associated with IPV (physical and/or sexual) to identify differences by HIV status. During 2015-16, random subset adults who participated first year PopART intervention were recruited standardised questionnaires administered. Logistic regression performed estimate...
ABSTRACT Introduction The HPTN071 (PopART) for Youth (P-ART-Y) study evaluated the acceptability and uptake of a community-level combination HIV prevention package including universal testing treatment (UTT) among young people in Zambia South Africa (SA). We determined whether four-question primary care level screening tool, validated use clinical settings, could enhance community (door-to-door) identification undiagnosed HIV-positive younger adolescents (aged 10-14) who are frequently left...