A5070211397- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Adolescent Sexual and Reproductive Health
- Pneumonia and Respiratory Infections
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Family and Patient Care in Intensive Care Units
- HIV, Drug Use, Sexual Risk
Desmond Tutu HIV Foundation
2020-2025
Stellenbosch University
2020-2025
BACKGROUND: South Africa has one the highest TB and HIV burdens globally. preventive therapy (TPT) reduces risk of disease TB-related mortality in adults children living with is indicated for use TB-exposed HIV-negative individuals children. TPT implementation remains suboptimal. METHODS: We conducted a pragmatic review using multiple data sources, including informant interviews ( n = 134), semi-structured observations 93) patient folder reviews 31 health facilities purposively selected...
Abstract Despite continued development of effective HIV treatment, expanded access to care and advances in prevention modalities, HIV‐related stigma persists. We examine how, the context a universal HIV‐testing treatment trial South Africa Zambia, increased availability services influenced conceptualisations HIV. Using qualitative data, we explore people’s stigma‐related experiences living ‘intervention’ ‘control’ study communities. conducted exploratory data analysis from cohort 150...
Tuberculous meningitis (TBM) occurs when tuberculosis (TB) bacilli disseminate and seed into the meninges, triggering a severe inflammatory response that often leads to brain infarction. It is most debilitating form of childhood TB with high mortality, children who survive TBM suffer lifelong physical neuro-disability resulting in emotional, social, economic burdens for families. In early stages symptoms may be non-specific so diagnosis made late patient already has significant injury. To...