A5100620734- Epilepsy research and treatment
- Vector-borne infectious diseases
- Parasitic Infections and Diagnostics
- Viral Infections and Vectors
- Mycobacterium research and diagnosis
- Influenza Virus Research Studies
- Tuberculosis Research and Epidemiology
- Vector-Borne Animal Diseases
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Glycogen Storage Diseases and Myoclonus
- Amoebic Infections and Treatments
- EEG and Brain-Computer Interfaces
- Insect symbiosis and bacterial influences
- Microbial infections and disease research
- Viral gastroenteritis research and epidemiology
- Helminth infection and control
- Antibiotics Pharmacokinetics and Efficacy
- Virus-based gene therapy research
- Animal Virus Infections Studies
- interferon and immune responses
- Respiratory viral infections research
- Functional Brain Connectivity Studies
- Insect and Pesticide Research
- Vestibular and auditory disorders
Inner Mongolia Agricultural University
2019-2025
Ministry of Agriculture and Rural Affairs
2021-2025
Air Force Medical University
2009-2024
Xijing Hospital
2011-2024
Sun Yat-sen University
2024
Icahn School of Medicine at Mount Sinai
2021-2024
Beijing Center for Disease Prevention and Control
2023
Guangzhou Medical University
2018-2020
Tarim University
2017-2019
Chongqing Medical University
2019
Enterocytozoon bieneusi is a zoonotic pathogen, with cattle serving as major reservoirs and important mediums for its transmission. However, data on the prevalence subtypes of E. in from Northern Shanxi Central Inner Mongolia, China, are limited. This study aimed to evaluate risk associated North Mongolia Connection Area. In this study, internal transcribed spacer (ITS) gene bieniusi was assessed. Fecal samples (n = 1338) were randomly collected 15 intensive free-range farms between 2021...
To investigate the blood oxygenation level-dependent (BOLD) signal changes correlated with ictal and interictal epileptic discharges using electroencephalography-correlated functional magnetic resonance imaging (EEG-fMRI) in patients eyelid myoclonia absences (EMA) then to explore pathophysiological mechanisms of their effect on brain function.Four EMA were investigated through method EEG-fMRI. The characteristics BOLD linked under different states consciousness explored.Seven sessions...
Influenza viruses undergo antigenic changes in the immuno-dominant hemagglutinin (HA) head domain, necessitating annual re-formulation of and re-vaccination with seasonal influenza virus vaccines for continuing protection. We previously synthesized mosaic HA (mHA) proteins B which redirect immune response towards immuno-subdominant conserved epitopes via sequential immunization. As ~90% current are manufactured using inactivated platform, we generated sequentially vaccinated mice displaying...
Cryptosporidium is a gastrointestinal protozoan that widely exists in nature, it an established zoonotic pathogen. Infected cattle are considered to be associated with cryptosporidiosis outbreaks humans. In the present study, we aimed assess prevalence and species distribution of dairy Central Inner Mongolia.We focused on small subunit ribosomal RNA gene (SSU rRNA) 60-kDa glycoprotein (gp60) parvum. We collected 505 manure samples from 6 sampling sites Mongolia 2021; were divided into 4...
Giardia duodenalis is a gastrointestinal protozoan ubiquitous in nature. It confirmed zoonotic pathogen, and cattle are considered source of giardiasis outbreaks humans. This study aimed to evaluate the prevalence multilocus genotype (MLG) G. dairy Central Inner Mongolia. was based on small subunit ribosomal RNA (SSU rRNA), glutamate dehydrogenase (gdh), triosephosphate isomerase (tpi), beta-giardin (bg) genes duodenalis. DNA extraction, polymerase chain reaction (PCR), sequence analysis...
Ticks are the second most significant vector of pathogens worldwide. Ixodes persulcatus is one dominant tick species in Inner Mongolia that can carry and transmit various pathogenic microorganisms. However, only specific pathogen has been detected a particular developmental stage I. persulcatus, moreover metagenomic analysis conducted adult stage. In this study, we used at different stages (first-generation female ticks, eggs, larval engorged nymphal second-generation ticks) from as...
Background: Paratuberculosis (PTB) is a chronic wasting disease mainly caused by Mycobacterium avium subsp. paratuberculosis (MAP) in ruminants. It difficult to diagnose, prevent, treat, and eradicate, thereby causing serious economic losses the livestock industry. Therefore, finding detection method with high sensitivity specificity crucial preventing controlling PTB. Methods: A total of 1585 fresh fecal samples were collected from 12 prefectures cities across Inner Mongolia between March...
Dermacentor is the most widely distributed tick genus in China. nuttalli, a predominant species Inner Mongolia, can carry and transmit pathogenic microorganisms. Here, D. nuttalli were collected from Ordos (O-D) Hinggan League (H-D) Mongolia. specimens at different developmental stages subsequently reared under identical laboratory conditions. Sample processing, nucleic acid extraction, high-throughput sequencing, microbial community analyses conducted. Bacterial communities O-D H-D...
Melophagus ovinus (sheep ked) is a blood-feeding ectoparasite that belongs to the family Hippoboscidae (Diptera: Hippoboscoidea) and mainly parasitizes sheep. The life-cycle of M. consists three stages: larva, pupa adult. It has worldwide distribution been found in four provinces China, especially South Xinjiang. In addition causing direct damage animal hosts, serves as vector for disease transmission. this study, our aim was investigate presence Anaplasma spp. pupal adult ovinus. A total 93...
To confirm that Bartonella and Wolbachia were carried by sheep keds (Melophagus ovinus) in southern Xinjiang of China, 17 M. ovinus samples, which collected Aksu Prefecture, Xinjiang, randomly selected. In this study, the gltA 16S rRNA gene amplified through conventional PCR sequence those products, analyzed. The results demonstrated was all 15 out them. identified as B. melophagi. Three strains supergroup F 1 strain has not been confirmed yet. It is first report about found provided...
Melophagus ovinus (sheep ked) is a blood-sucking ectoparasite that parasitic primarily on sheep. It widely distributed in different geographical regions worldwide. In China, it has been mainly found Xinjiang, Gansu, and Tibet recent years. addition to causing direct damage the animal hosts, M. also carries pathogens serves as vector for disease transmission. Border virus (BDV) positive-sense, single-stranded RNA pestivirus infects causes border (BD) sheep goats Since 2012, this reported 4...
A comparative in vivo pharmacokinetic (PK) study of tilmicosin (TIL) was conducted 6 crossbred healthy pigs and infected with Haemophilus (H.) parasuis following oral administration a single 40 mg/kg dose. The model established by intranasal inoculation confirmed clinical signs, blood biochemistry, microscopic examinations. Plasma TIL concentrations were determined validated high-performance liquid chromatography method ultraviolet detection at 285 nm. PK parameters calculated using...
Abstract Theileria spp. are tick-transmitted, intracellular apicomplexan protozoan parasites that infect a wide range of animals and, as such, can cause significant economic losses. The aim the present study was to detect and analyze from two different ectoparasites were collected Xinjiang Uygur Autonomous Region, China. PCR-based detection 18S rRNA indicated Ornithodoros lahorensis specimens Kashgar, Xinjiang, Aksu positive for spp., Melophagus ovinus Aksu. Meanwhile, phylogenetic analysis,...
We have developed a new universal influenza B vaccination strategy based on inactivated viruses displaying mosaic hemagglutinins (mHAs). Recombinant mHA were constructed by replacing the four major antigenic sites of virus HAs, with those from exotic avian A HAs. Sequential naïve mice mHA-based vaccines elicited higher immune responses towards immuno-subdominant conserved epitopes HA than wildtype viruses. Among different preparations tested, split less immunogenic their whole counterparts....
Livestock husbandry is vital to economy of the Tarim Basin, Xinjiang Autonomous Region, China. However, there have been few surveys distribution ixodid ticks (Acari: Ixodidae) and tick-borne pathogens affecting domestic animals at these locations. In this study, 3,916 adult infesting were collected from 23 sampling sites during 2012-2016. Ticks identified species based on morphology, identification was confirmed mitochondrial 16S 12S rRNA sequences. Ten tick belonging 4 genera identified,...
As a generalized form of nonconvulsive status epilepticus (NCSE), absence is the most common form. It manifests as prolonged, confusional states varying severity, and continuous or repetitive discharges spikes, multiple slow waves on EEG. Jeavons syndrome (JS) new type epilepsy syndrome. Hitherto, only four sets monozygotic twin with JS have been reported. Absence occurring in twins not Here we report male Chinese origin JS. Both them presented eyelid myoclonia absences.
Argasid ticks (Acari: Argasidae) carry and transmit a variety of pathogens animals humans, including viruses, bacteria parasites. There are several studies reporting ixodid Ixodidae) associated tick-borne in Xinjiang, China. However, little is known about the argasid tick-associated this area. In study, total 3829 adult infesting livestock were collected at 12 sampling sites 10 counties Peripheral Oases, which 90% humans population, around Tarim Basin (southern Xinjiang) from 2013 to 2016....