A5103262315- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Phytochemical Studies and Bioactivities
- Plant biochemistry and biosynthesis
- Sesquiterpenes and Asteraceae Studies
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Plant Toxicity and Pharmacological Properties
- Phytochemical compounds biological activities
- Metabolomics and Mass Spectrometry Studies
- Traditional Chinese Medicine Studies
- Ginseng Biological Effects and Applications
- Medicinal plant effects and applications
- Phytochemistry and Bioactive Compounds
- Chromatography in Natural Products
- Food Quality and Safety Studies
- Magnolia and Illicium research
- Plant-derived Lignans Synthesis and Bioactivity
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Morinda citrifolia extract uses
- Phytochemistry and biological activity of medicinal plants
- Flavonoids in Medical Research
Inner Mongolia Agricultural University
2025
Shanghai University of Traditional Chinese Medicine
2018-2024
Guangdong Food and Drug Vocational College
2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2024
Kanion Pharmaceutical (China)
2024
Shanghai International Studies University
2024
Shanghai University
2024
Second Military Medical University
2008-2017
Fujian University of Traditional Chinese Medicine
2013-2017
Shanghai Changzheng Hospital
2009-2012
Bioactivity-guided fractionation led to the successful isolation of antiosteoporotic components, i.e. physicion (1), rubiadin-1-methyl ether (2), 2-hydroxy-1-methoxy- anthraquinone (3), 1,2-dihydroxy-3-methylanthraquinone (4), 1,3,8-trihydroxy-2-methoxy- (5), 2-hydroxymethyl-3-hydroxyanthraquinone (6), 2-methoxyanthraquinone (7) and scopoletin (8) from an ethanolic extract roots Morinda officinalis. Compounds 4-8 are isolated for first time M. Among them, compounds 2 3 promoted osteoblast...
Isatis indigotica is a widely used herb for the clinical treatment of colds, fever, and influenza in Traditional Chinese Medicine (TCM). Various structural classes compounds have been identified as effective ingredients. However, little known at genetics level about these active metabolites. In present study, we performed de novo transcriptome sequencing first time to produce comprehensive dataset I. indigotica. A database 36,367 unigenes (average length = 1,115.67 bases) was generated by...
In the present study, anxiolytic and sedative-hypnotic activities of polygalasaponins extracted from Polygala tenuifolia Willdenow (Polygalaceae) were determined in mice using hole-board, elevated plus maze, open field, sodium pentobarbital-induced hypnosis tests. Moreover, acute toxicity was also estimated mice. Sixty minutes after p.o. administration (40, 80, 160 mg/kg) mice, central crossing counts percentage central/total ambulation significantly increased number rearings defecations...
The protective effects of Semen Hoveniae extract (SHE) from Hovenia dulcis Thunb. (Rhamnaceae) on acute alcohol-induced liver injury were investigated in vivo using mice as test models. In the present study, SHE (150, 300, 600 mg/kg/day) was given to by intragastric administration for 4 days. Mice gavaged with 60% ethanol 10 mL/kg after last dose extract. Six hours alcohol administration, evaluated biochemical examination. Lipid peroxidation and activity antioxidants measured...
1. Antithrombotic agents are effective in the treatment of ischaemic stroke. Timosaponin B-II (TB-II) is a major active component Anemarrhena asphodeloides Bunge (Liliaceae; rhizome) that has protective effects against cerebral damage. The present study examined antiplatelet and antithrombotic actions TB-II. 2. In vitro experiments, TB-II (20, 40 80 mg/mL) potently dose-dependently inhibited ADP-induced platelet aggregation. Furthermore, 1, 3 6 mg/kg prolonged activated partial...
Two new polyphenols, penthorumin C (1) and 2,6-dihydroxyacetophenone-4-O- [4ꞌ,6ꞌ-(S)-hexahydroxydiphenoyl]-β-D-glucose (2), along with four known polyphenolic acids, pinocembrin-7-O-[4ꞌꞌ,6ꞌꞌ-hexahydroxydiphenoyl]-β-D-glucose(3), pinocembrin-7-O-[3ꞌꞌ-O- galloyl- 4ꞌꞌ,6ꞌꞌ-hexahydroxydiphenoyl]-β-D-glucose (4), thonningianin A (5), B (6) were isolated from Penthourm chinense. All compounds evaluated for their anti-proliferative activity in HSC-T6 cells, 2 5 showed significant activity, IC50...