A5102011645- Hydrogen Storage and Materials
- Fusion materials and technologies
- Nuclear Materials and Properties
- Mycorrhizal Fungi and Plant Interactions
- Soil Carbon and Nitrogen Dynamics
- Light effects on plants
- Ultrasound and Cavitation Phenomena
- RNA modifications and cancer
- Plant nutrient uptake and metabolism
- Ferroptosis and cancer prognosis
- Innovations in Aquaponics and Hydroponics Systems
- Agriculture, Soil, Plant Science
- Growth and nutrition in plants
- Meningioma and schwannoma management
- Phytase and its Applications
- MicroRNA in disease regulation
- Cold Fusion and Nuclear Reactions
- Phosphorus and nutrient management
- Plant Physiology and Cultivation Studies
- Circular RNAs in diseases
- Parasitic infections in humans and animals
- Ultrasound and Hyperthermia Applications
- Impact of Light on Environment and Health
- Vascular Malformations Diagnosis and Treatment
- Agricultural Productivity and Crop Improvement
New York University
2020-2022
Institute for Systems Biology
2020-2022
Chinese Academy of Agricultural Sciences
2006-2022
Institute of Environment and Sustainable Development in Agriculture
2006-2022
Shenzhen University
2022
University of Birmingham
2015-2022
Sichuan University
2008-2022
West China Hospital of Sichuan University
2017-2022
Ministry of Agriculture and Rural Affairs
2022
Institute of Process Engineering
2022
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization 110 tumors 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale proteomics, phosphoproteomics, acetylproteomics. Multi-omics clustering revealed four subgroups defined by key driver mutations, country, gender. Proteomic phosphoproteomic data illuminated downstream copy number aberrations, somatic...
We undertook a comprehensive proteogenomic characterization of 95 prospectively collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This analysis revealed possible new consequences perturbations to the p53 Wnt/β-catenin pathways, identified potential role for circRNAs in epithelial-mesenchymal transition, provided information about proteomic markers clinical genomic tumor subgroups, including relationships known druggable pathways. An extensive genome-wide...
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few therapeutic options. We characterized the proteogenomic landscape LSCC, providing deeper exposition LSCC biology potential implications. identify NSD3 as an alternative driver in FGFR1-amplified tumors and low-p63 overexpressing target survivin. SOX2 is considered undruggable, but our analyses provide rationale for exploring chromatin modifiers such LSD1 EZH2 to SOX2-overexpressing tumors. Our data support...
Clear cell renal carcinomas (ccRCCs) represent ∼75% of RCC cases and account for most RCC-associated deaths. Inter- intratumoral heterogeneity (ITH) results in varying prognosis treatment outcomes. To obtain the comprehensive profile ccRCC, we perform integrative histopathologic, proteogenomic, metabolomic analyses on 305 ccRCC tumor segments 166 paired adjacent normal tissues from 213 cases. Combining histologic molecular profiles reveals ITH 90% ccRCCs, with 50% demonstrating immune...
When a microbubble is subject to ultrasound, non-spherical oscillation or surface modes can be generated after many acoustic cycles. This phenomenon has wide applications, including ultrasonic cleaning, sonochemistry, and biomedical ultrasonics. Yet, the nonlinear development of bubble shape over dozens cycles not well understood. Here, we describe grid-free robust model simulate phenomenon. A viscous pressure correction introduced compensate non-zero tangential stress at free in potential...
A bubble initiated near a rigid boundary may be almost in contact with the because of its expansion and migration to boundary, where thin layer water forms between thereafter. This phenomenon is modelled using weakly compressible theory coupled integral method. The wall effects are imaging numerical instabilities caused by surface handled removing them joining image boundary. Our computations correlate well experiments for both first second cycles oscillation. time history energy system...
Abstract A glasshouse study was conducted to investigate the symbiotic efficiency and soil adaptability of four AMF using glass-bead cultivation systems. The results showed that fungi varied among three soils. Particularly, BEG167 shifted from positive in Beijing negative Guangdong soil. Furthermore, had high all Intraspecific differences BRG168 BEG221 were found Taking adaptabilty into consideration, it concluded BEG167, BEG168 soil, BEG151 Hubei effective for maize.