Louis Marcellin

ORCID: 0000-0003-4482-9710
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About
Contact & Profiles
Research Areas
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Reproductive System and Pregnancy
  • Gynecological conditions and treatments
  • Endometrial and Cervical Cancer Treatments
  • Ovarian function and disorders
  • Pregnancy-related medical research
  • Maternal and fetal healthcare
  • Preterm Birth and Chorioamnionitis
  • Pregnancy and preeclampsia studies
  • Reproductive Biology and Fertility
  • Ectopic Pregnancy Diagnosis and Management
  • Assisted Reproductive Technology and Twin Pregnancy
  • Maternal and Perinatal Health Interventions
  • Sarcoma Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Breastfeeding Practices and Influences
  • Bone Tumor Diagnosis and Treatments
  • Reproductive Health and Technologies
  • Oral and Maxillofacial Pathology
  • Intestinal and Peritoneal Adhesions
  • Renal and related cancers
  • Urological Disorders and Treatments
  • Maternal Mental Health During Pregnancy and Postpartum
  • Renal cell carcinoma treatment

Groupe Hospitalier Cochin - Port-Royal, Hôtel-Dieu, Broca - La Collégiale
2015-2025

Institut Cochin
2016-2025

Inserm
2016-2025

Assistance Publique – Hôpitaux de Paris
2016-2025

Université Paris Cité
2016-2025

Sorbonne Paris Cité
2015-2025

Maternité Port Royal
2015-2024

Centre National de la Recherche Scientifique
2012-2024

Hôpital Cochin
2015-2024

University of Miami
2024

What is the relationship between endometriosis phenotypes superficial peritoneal (SUP), ovarian endometrioma (OMA), deep infiltrating (DIE) and adenomyosis appearance by magnetic resonance imaging (MRI)? Focal located in outer myometrium (FAOM) was observed more frequently women with endometriosis, significantly associated DIE phenotype. An association has been reported previously, although data regarding MRI of phenotype are currently still lacking. This an observational, cross-sectional...

10.1093/humrep/dex088 article EN Human Reproduction 2017-04-24

PURPOSE The usual therapy of osteosarcoma is neoadjuvant chemotherapy, followed by surgery, then postoperative chemotherapy. There no prognostic factor to predict, at diagnosis, the histologic response and final outcome. Inactivation retinoblastoma-susceptibility gene RB associated with pathogenesis several human cancers. In primary osteosarcomas, loss heterozygosity (LOH) locus has been found in greater than 60% cases. aim this study was determine potential early value LOH on biopsy...

10.1200/jco.1996.14.2.467 article EN Journal of Clinical Oncology 1996-02-01

STUDY QUESTIONAre protein oxidative stress markers [thiols, advanced oxidation products (AOPP), carbonyls and nitrates/nitrites] in perioperative peritoneal fluid higher women with histologically proven endometriosis when compared endometriosis-free controls?

10.1093/humrep/deu290 article EN Human Reproduction 2014-11-05

Do adenomyosis phenotypes such as external or internal adenomyosis, diagnosed by MRI, have the same clinical characteristics?External was found more often in young and nulliparous women associated with deep infiltrating endometriosis, whereas, contrast, heavy menstrual bleeding (HMB) but no differences were noted terms of pain symptoms.Adenomyosis is characterized presence endometrial glands stroma within myometrium, giving rise to dysmenorrhea, pelvic menorrhagia. Various forms been...

10.1093/humrep/deaa307 article EN Human Reproduction 2020-10-21

The time between symptoms onset and endometriosis diagnosis is usually long. negative impacts of delayed can affect patients health outcomes.We conducted a case-control study using clinical epidemiological data extracted from prospective pre-operative patient questionnaire compared with histologically proven no at surgical exploration 2005 to 2018, in French referral center. We used the beta coefficients significant variables introduced multiple regression model devise score (score 1),...

10.1016/j.eclinm.2021.101263 article EN cc-by-nc-nd EClinicalMedicine 2022-01-10

Endometriosis is a complex disease and still many areas of uncertainty exist on the clinical management, from diagnosis to treatment. The modern diagnostic workup should include family history (including genetic epigenetic factors), presentation, an accurate gynecological examination imaging evaluation (transvaginal ultrasound and/or magnetic resonance) performed by expert practitioners. Laparoscopy must no longer be with sole purpose diagnosing endometriosis. Furthermore, endometriosis...

10.1016/j.jeud.2024.100062 article EN cc-by-nc-nd Journal of Endometriosis and Uterine Disorders 2024-01-22

Background Controlled ovarian stimulation in assisted reproduction technology (ART) may alters endometrial receptivity by an advancement of development. Recently, technical improvements vitrification make deferred frozen-thawed embryo transfer (Def-ET) a feasible alternative to fresh (ET). In endometriosis-related infertility the eutopic endometrium is abnormal and its functional alterations are seen as likely alter quality receptivity. One question endometriosis ART-management know whether...

10.1371/journal.pone.0194800 article EN cc-by PLoS ONE 2018-04-09

Were spontaneous miscarriages more frequent in women with histologically proven endometriosis when compared endometriosis-free controls? Endometriosis-affected display a significantly higher rate of previous than controls. The association between and has long been debated without reaching consensus. We conducted retrospective cohort study comparing exposed (endometriosis) control (without endometriosis) regarding the incidence miscarriages. All participants underwent surgery for benign...

10.1093/humrep/dew035 article EN Human Reproduction 2016-03-09

Endometriosis is a frequent, chronic, inflammatory gynecological disease characterized by the presence of ectopic endometrial tissue causing pain and infertility. Macrophages have central role in lesion establishment maintenance driving chronic inflammation remodeling. can be reprogrammed to acquire memory-like characteristics after antigenic challenge reinforce or inhibit subsequent immune response, phenomenon termed "trained immunity." Here, whereas bacille Calmette-Guérin (BCG) training...

10.1016/j.celrep.2020.108325 article EN cc-by Cell Reports 2020-11-01
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