- Neuroscience and Neuropharmacology Research
- Mitochondrial Function and Pathology
- RNA and protein synthesis mechanisms
- Cellular transport and secretion
- Adipose Tissue and Metabolism
- Olfactory and Sensory Function Studies
- Genetic Neurodegenerative Diseases
- Amyotrophic Lateral Sclerosis Research
- Dermatology and Skin Diseases
- Retinal Development and Disorders
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Neuroscience of respiration and sleep
- Neuroendocrine regulation and behavior
- Cancer, Hypoxia, and Metabolism
- Sleep and Wakefulness Research
- Bacteriophages and microbial interactions
- Renin-Angiotensin System Studies
- Memory and Neural Mechanisms
- Urological Disorders and Treatments
- Electrochemical Analysis and Applications
- Dendrimers and Hyperbranched Polymers
- Viral Infections and Immunology Research
- Autophagy in Disease and Therapy
Northwestern University
2015-2021
University of Cambridge
2020-2021
University of Vermont
2018
University of Manchester
2012
Arsenal Medical (United States)
1987
Wycombe General Hospital
1982
University of Copenhagen
1975
University of Ottawa
1963-1974
Aarhus University
1971
University of Oslo
1969
The sensation of itch and the scratch response elicited by application histamine are enhanced itch-related visual cues in people with existing skin conditions and, to a lesser extent, healthy controls. We tested whether alone could generate feelings provoke volunteers. A secondary aim was assess content some pictures evoked these sensations more effectively. Thirty participants viewed static images that were either (e.g. ants, fleas or conditions) neutral butterflies skin). These further...
Abstract Autophagy has emerged as a mechanism critical to both tumorigenesis and development of resistance multiple lines anti‐cancer therapy. Therefore, targeting autophagy alternative cell death pathways arisen viable strategy for refractory tumors. The anti‐malarial 4‐aminoquinoline compounds chloroquine hydroxychloroquine are currently being considered re‐purposing therapies intended sensitize different tumors by the lysosomal pathway. Here, we describe novel organometallic derivative,...
benoxaprofen damage was reduced; this may be due to a subclinical photosensitivity reaction, as occurs with onycholysis, which not associated obvious sun sensitivity.It is yet clear whether the hypertrichosis simply secondary photosensitivity, seen in porphyria4 and when alopecia areata treated ultraviolet B or psoralen-ultraviolet A, different mechanism entailed, minoxidil.5
Phagolessin A58, an antibiotic substance active against a number of bacterial viruses, was studied for activity the seven T phages. Only three phages-T1, T3, and T7-proved to be sensitive antibiotic. The caused direct, apparently irreversible inactivation free phage particles. A study properties inactivated particles showed that retained ability kill host cells exert mutual exclusion unrelated after infectivity lost. There progressive loss in these two when higher concentrations were used...
SUMMARY While many neuronal membrane-anchored proteins undergo proteolytic cleavage, little is known about the biological significance of ectodomain shedding. Using mass spectrometry (MS)-based proteomics, we showed that sheddome mirrors human cerebrospinal fluid (hCSF). Among shed synaptic in hCSF was CNTNAP2 (CNTNAP2-ecto), a risk factor for neurodevelopmental disorders (NDD). structured-illumination microscopy (SIM), mapped spatial organization CNTNAP2-ecto affinity chromatography...
A forerunner in implementing wirelessly controlled LED technology, Los Angeles's street lighting program is second size only
Itching is a common subjective sensation experienced on the skin and associated with desire impulse to scratch. We tested whether visual cues could generate feelings of itch provoke scratch response in healthy volunteers. A secondary aim was assess certain pictures were more effective evoking sensations itch. Thirty participants viewed static images that either be itch-related (i.e., viewing ants or conditions) neutral (viewing butterflies skin). These further separated by picture type:...