Paul Frenkel

ORCID: 0000-0003-4498-4016
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About
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Research Areas
  • Non-Invasive Vital Sign Monitoring
  • Hemodynamic Monitoring and Therapy
  • Acoustic Wave Phenomena Research
  • Underwater Acoustics Research
  • Pulmonary Hypertension Research and Treatments
  • Speech and Audio Processing
  • Heart Rate Variability and Autonomic Control
  • Respiratory Support and Mechanisms
  • Electrical and Bioimpedance Tomography
  • Sepsis Diagnosis and Treatment
  • Thermal Regulation in Medicine

University of Rostock
2019-2025

University Medical Center
2024

University Hospital and Clinics
2024

Abstract Background Gravity‐dependent positioning therapy is an established concept in the treatment of severe acute respiratory distress syndrome and improves oxygenation spontaneously breathing patients with hypoxemic failure. In coronavirus disease 2019, this seems to be less effective. Electrical impedance tomography as a point‐of‐care functional imaging modality for visualizing regional ventilation can possibly help identify who might benefit from guide those maneuvers real‐time....

10.1111/aas.14161 article EN cc-by-nc-nd Acta Anaesthesiologica Scandinavica 2022-10-21

Abstract Objective . Since pulse wave transit time (PWTT) shortens as pulmonary artery pressure (PAP) increases it was suggested a potential non-invasive surrogate for PAP. The state of tidal lung filling is also known to affect PWTT independently aim this retrospective analysis test whether respiratory gating improved the correlation coefficient between and Approach In each one five anesthetized mechanically ventilated pigs two high-fidelity catheters were placed, directly behind valve,...

10.1088/1361-6579/ad2eb5 article EN cc-by Physiological Measurement 2024-02-29

Pulse wave transit time (PWTT) shortens as pulmonary artery pressure (PAP) increases and was therefore suggested a surrogate parameter for PAP. The aim of this analysis to reveal patterns potential mechanisms ventilation-induced periodic changes in PWTT under resting conditions. To measure both PAP five healthy pigs, two Mikro-Tip™ catheters were inserted into the vasculature: one with tip placed trunk, second distal segment artery. Animals received pressure-controlled mechanical...

10.3390/biomedicines11010182 article EN cc-by Biomedicines 2023-01-11

Pulse pressure variation (PPV) and stroke volume (SVV), which are based on the forces caused by controlled mechanical ventilation, commonly used to predict fluid responsiveness. When PPV SVV were introduced into clinical practice, volume-controlled ventilation (VCV) with tidal volumes (VT) ≥ 10 ml kg- 1 was most used. Nowadays, lower VT use of pressure-controlled (PCV) has widely become preferred type ventilation. Due their specific flow characteristics, VCV PCV result in different airway...

10.1186/s12871-023-02273-z article EN cc-by BMC Anesthesiology 2023-09-19
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