- Ocular and Laser Science Research
- Laser Applications in Dentistry and Medicine
- Optical Coherence Tomography Applications
- Laser Material Processing Techniques
- Dermatologic Treatments and Research
- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Photodynamic Therapy Research Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Visual perception and processing mechanisms
- Solid State Laser Technologies
- Medical and Biological Ozone Research
- Radiation Detection and Scintillator Technologies
- Intensive Care Unit Cognitive Disorders
- Bee Products Chemical Analysis
- Infrared Target Detection Methodologies
- Medical Imaging Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Photonic Crystal and Fiber Optics
- Atmospheric aerosols and clouds
- Spectroscopy and Laser Applications
- Mitochondrial Function and Pathology
- Photoacoustic and Ultrasonic Imaging
- Wound Healing and Treatments
- Advanced Fiber Laser Technologies
Beijing Radiation Center
2019-2025
Shaanxi Provincial People's Hospital
2025
Shanxi Medical University
2025
With the increasing use of diode lasers emitting in visible light spectrum, concerns about their potential to dazzle and cause eye damage have grown. This study aims determine maximum safe exposure levels evaluate retinal dazzling effects caused by red, green, blue, synthetic white lasers. A chinchilla grey rabbit model was used for experimentation. Lasers with wavelengths 635 nm (red), 520 (green), 456 (blue), along combined output as light, were directed at rabbits' eyes 0.2 s. Retinal...
Septic cardiomyopathy is a considerable complication in sepsis, which has high mortality rates and an incompletely understood pathophysiology, hinders the development of effective treatments. α‑ketoglutarate (AKG), component tricarboxylic acid cycle, serves role cellular metabolic regulation. The present study delved into therapeutic potential underlying mechanisms AKG ameliorating septic cardiomyopathy. A mouse model sepsis was generated treated with via drinking water. Cardiac function...
To investigate the associated factors concerning collagen and expression of apoptosis-related proteins in porcine skin injuries induced by laser exposure, live pig was irradiated at multiple spots one time, using a grid-array method with 1064 nm different power outputs. The healing process laser-treated areas, alterations structure, changes apoptosis were continuously observed analyzed from 6 h to 28 days post-irradiation. On 28th day following wound contraction recovery notably sluggish...
Background and Objectives Laser‐induced thermal injuries are a heavily researched topic in laser medicine biomedicine. To explore the quantitative biological effects of laser‐induced injury repair, we propose an optical imaging‐based vivo evaluation method discuss effect repair characteristics skin tissue. Study Design/Materials Methods A supercontinumm (spectrum width ranged from 400 to 2400 nm) was used irradiate live mice. The radiation doses were set as 32.85, 65.69, 98.4, 197.08 J/cm 2...
To investigate the associated mechanisms concerning collagen and expression of apoptosis-related proteins in porcine skin injuries induced by laser exposure, pig was treated with a 1064 nm laser. The healing process laser-treated areas, alterations structure, changes apoptosis were continuously observed analyzed from 6 hours to 28 days post-irradiation. On 28th day following wound contraction recovery notably sluggish medium-high dose groups, displaying more premature delicate type III...
Evaluation of skin recovery is an important step in the treatment burns. However, conventional methods only observe surface and cannot quantify injury volume. Optical coherence tomography (OCT) a non-invasive, non-contact, real-time technique. Swept source OCT uses near infrared light analyzes intensity echo at different depths to generate images from optical interference signals. To dynamic burns over time, laser induced mice were evaluated using deep learning images. A laser-induced mouse...
Abstract Background and Objective Lasers are widely employed in clinical applications. In vivo monitoring of real‐time information about different‐wavelength laser surgeries would provide important surgical feedback for surgeons or therapy instruments. However, the quantitative effect ablation vaporization still needs to be further explored investigated. Here, we investigate quantitatively evaluate variations morphological changes two models: point‐ sweeping‐based models. Methods An infrared...
OSL detectors offer significant advantages for radiation dose measurement, including compact size and compatibility with optoelectronic devices, enabling detection at considerable distances from the source, a feature not readily achievable conventional systems. To this end, remote sensor, employing Al2O3:C as medium, 520 nm laser excitation, quartz optical fibers transmission of both excitation light emitted fluorescence, PMT photoelectric conversion, photon counter signal quantification,...
No report has been made on the properties of radiation dose rate detection using GAGG: Ce scintillator radioluminescence (RL). This reveals for first time scintillators combined with photomultiplier tubes (PMTs) as detectors optical fibers. We have thoroughly investigated performance two different sizes scintillators. The experimental results show that combination RL signal PMT can be used to accurately measure during irradiation. At a constant 10 μsv/h, stability count irradiation was kept...
Abstract To quantitatively evaluate the dazzling effect of each spectrum band supercontinuum laser, we conducted experimental research to explore safety and animal eyes. Under condition dark adaptation, rabbit eyes were irradiated with different power densities spectral bands by frontal incident mode for 0.25 s, which was repeated ten times. The fundus examined using an ophthalmoscope, upper limit safe density explored. Rabbit doses light 0.1 s. Visual electrophysiological signals collected...
The natural antimicrobial resistance of Pseudomonas aeruginosa (P. aeruginosa) represents a serious therapeutic challenge to antibiotic therapy approaches in clinical caring. As new non-antibiotic approach, the bactericidal effect 470 nm blue light on P. has been reported and investigated. However, relationships between ratio irradiation doses have not reported, mechanism explicated. In this paper, effects LED are suspensions irradiated with (100 mW cm−2) different time, then number...
Abstract Background: Laser eye dazzling affects the visual performance through instant high-intensity light stimulation. The temporary loss or deterioration of function may occur when radiated by lasers. To quantitatively evaluate effect each spectrum band supercontinuum laser, we conducted an experimental research for exploring safety and animals’ eyes. Methods: Under condition dark adaption, laser with different power densities spectral bands was output, rabbit eyes were normal incident...