A5101601702- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Polysaccharides and Plant Cell Walls
- Natural product bioactivities and synthesis
- Metabolomics and Mass Spectrometry Studies
- Food Quality and Safety Studies
- Polysaccharides Composition and Applications
- Fungal Biology and Applications
- Exercise and Physiological Responses
- Aquatic Ecosystems and Phytoplankton Dynamics
- Seaweed-derived Bioactive Compounds
- Phytochemicals and Antioxidant Activities
- Medicinal Plants and Bioactive Compounds
- Postharvest Quality and Shelf Life Management
- Ziziphus Jujuba Studies and Applications
- Marine Toxins and Detection Methods
- Meat and Animal Product Quality
- melanin and skin pigmentation
- Urinary Bladder and Prostate Research
- Biopolymer Synthesis and Applications
- Mitochondrial Function and Pathology
- Per- and polyfluoroalkyl substances research
- Cardiovascular Disease and Adiposity
- Tea Polyphenols and Effects
Changchun University of Chinese Medicine
2012-2025
Shaanxi Provincial People's Hospital
2025
Shanxi Medical University
2025
Huazhong Agricultural University
2024
Wuhan Polytechnic University
2023-2024
China Agricultural University
2012-2019
Jilin University
2007-2018
First Hospital of Jilin University
2007-2018
Guilin Medical University
2017
Changzhi Medical College
2016
Color is an important appearance attribute of fruits and vegetables during drying processing, as it influences consumer's preference acceptability. Establishing color change kinetics model effective way for better understanding the quality changes optimization process. However, difficult to quickly accurately predict highly nonlinear, complex, dynamic, multivariable. To alleviate this problem, a new based on extreme learning machine integrated Bayesian methods (BELM) has been developed...
Two polysaccharides were obtained from steamed ginseng via ultrafiltration, and their physical–chemical properties, solution properties antifatigue activities studied. WSGP-S3 WSGP-G3 acid heteropolysaccharides with the molecular weights of 2.03 × 10 4 4.86 , respectively. They composed different molar ratios monosaccharides Rha, GlcA, GalA, Glc, Gal, Ara. The results size-exclusion chromatography–multiangle laser light scattering analysis, Conge red staining Circular dichroism spectroscopy...
Panax ginseng C. A. Meyer (Araliaceae) is a tonic herb used in ancient Asia.This study investigated the antifatigue effect of P. on chronic fatigue rats.Sprague-Dawley rats were divided into control, model and EEP (ethanol extraction roots) (50, 100 200 mg/kg) groups (n = 8). The subcutaneously handled with loaded swimming once daily for 26 days, except control group. animals intragastrically treated from 15th day. On day 30, serum, liver muscles collected, PI3K/Akt/mTOR signalling pathway...
Triol-type ginsenoside Re (GS-Re) exhibits potent anti-myocardial ischemia-reperfusion effects, but its clinical use is hindered by poor bioavailability. This study evaluates the impact of β-cyclodextrin (β-CD) inclusion on GS-Re bioavailability and tissue dynamics in rat models. The GS-Re-β-CD complex was prepared using aqueous stirring characterized. Male Wistar rats (200 ± 20 g) were administered at a dose 500 mg/kg. Plasma concentrations quantified UHPLC-MS/MS to evaluate...
A rapid resolution liquid chromatography coupled with quadruple-time-of-flight mass spectrometry (RRLC-Q-TOF-MS) method was developed for analysis of chemical transformation 20(S)-protopanaxatriol (PPT)-type ginsenosides Re, Rg2, and Rf in acidic conditions. The products were identified by comparing the retention time standard compounds, accurate measurement, fragment ions obtained from RRLC-Q-TOF-tandem (MS/MS) analyses. specific product aglycone PPT (m/z 475), C-24- C-25-hydrated 493),...
Panax ginseng was employed in the treatment of "Xiao-Ke" symptom, which nowadays known as diabetes mellitus, traditional Chinese medicine for more than a thousand years. Ginsenoside Re major pharmacologic ingredient found abundantly ginseng. However, anti-diabetic and its underlying mechanism metabolic level are still unclear. Serum urine metabolomic method carried out to investigate pharmacological effects potential on high-fat diet combined streptozotocin-induced type 2 mellitus (T2DM)...
Septic cardiomyopathy is a considerable complication in sepsis, which has high mortality rates and an incompletely understood pathophysiology, hinders the development of effective treatments. α‑ketoglutarate (AKG), component tricarboxylic acid cycle, serves role cellular metabolic regulation. The present study delved into therapeutic potential underlying mechanisms AKG ameliorating septic cardiomyopathy. A mouse model sepsis was generated treated with via drinking water. Cardiac function...
It has been previously demonstrated that microRNA (miR)-25 plays critical roles in collagen deposition. Ischemia/reperfusion injury to the myocardium results fibrosis and However, whether miR-25 is involved development of hypoxia/reoxygenation (H/R)‑induced cardiomyocytes or not remains largely unknown. For this purpose, present study, cardiomyocyte H9c2 cells were subjected H/R. The techniques flow cytometry, western blot analysis RT-qPCR used we observed increases cell apoptosis rate as...
This review summarizes the current status of mass spectrometry (MS)-based techniques used in ginseng research. The has been explored from two parts. first part presents an overview chemical analysis based on MS and liquid chromatography – (LC-MS), including application MS/MS systematic structural characterization ginsenosides fragmentation patterns different metal adducts with ginsenoside for structure analysis, crude extracts by LC-MS, investigation hydrolysis changes related prescription...
Abstract Ginsenoside has been used to treat diabetes, while ginsenoside Rg3 is the main active ingredient component of ginseng and study its effects on lung tissue damage in diabetic rats. In this paper, 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assay flow cytometry were applied detect proliferation apoptosis BEAS‐2B cells treated with different concentrations Rg3. The inflammatory response pathological change rats evaluated by enzyme‐linked immunosorbent assay, quantative...
The algicidal bacterium Pseudomonas aeruginosa ACB3 effectively inhibited the growth and maximum quantum efficiency (Fv/ Fm) of unicellular Microcystis strains, but hardly Fv/ Fm colonial strains. Interestingly, decreased colony size Microcystis. Considering that occurs mainly as aggregates in nature, our results will help understand role bacteria affecting