- Peripheral Artery Disease Management
- Erythropoietin and Anemia Treatment
- Vascular Procedures and Complications
- Vascular anomalies and interventions
- 3D Printing in Biomedical Research
- Aortic aneurysm repair treatments
- Angiogenesis and VEGF in Cancer
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Amoebic Infections and Treatments
- Facial Nerve Paralysis Treatment and Research
- Intraperitoneal and Appendiceal Malignancies
- Infective Endocarditis Diagnosis and Management
- Abdominal vascular conditions and treatments
- Abdominal Surgery and Complications
- Neurosurgical Procedures and Complications
- Body Contouring and Surgery
- Appendicitis Diagnosis and Management
- Liver Disease and Transplantation
- Traumatic Brain Injury and Neurovascular Disturbances
- Turtle Biology and Conservation
- Infectious Aortic and Vascular Conditions
- Pneumothorax, Barotrauma, Emphysema
- Urologic and reproductive health conditions
University Hospitals Sussex NHS Foundation Trust
2019-2025
University Hospitals Bristol NHS Foundation Trust
2014
Frenchay Hospital
2014
North Bristol NHS Trust
2014
Royal Sussex County Hospital
2014
University College London
2010-2013
Bristol Royal Infirmary
2012
The Royal Free Hospital
2010-2011
Watford General Hospital
2006-2010
Center for Vascular Biology Research
2010
Tamoxifen (Tx) has been used in breast cancer treatment and prophylaxis because of its antiestrogenic activity; however, Tx may also have beneficial cardiovascular effects other actions mediated by mechanisms than estrogen receptors. Previous studies showing interactions with Ca+(+)-channel blockers suggested that affect Ca++ channels, an hypothesis was investigated using whole cell patch clamp techniques vascular smooth muscle cells (cell line A7r5 freshly dissociated cells) determining on...
<title>Abstract</title> <bold>Background</bold> Ascites remains the most common complication of cirrhosis and a frequent reason for hospitalisation in advanced chronic liver disease (ACLD). is associated with significant symptom burden, caregiver workload poor health-related quality life (HRQoL). Once refractory to treatment, median survival poor. Many ascites (RA) will neither receive transjugular intrahepatic portosystemic shunt (TIPS) nor transplant. Palliative care underutilised...
Hie-tie and great saphenous vein (GSV) stripping decreases recurrence of varicose veins (VVs). However, varying lengths residual-GSV are observed in patients with previous GSV stripping. This may explain high rates VVs. The proportion recurrent VV occurring secondary to suboptimal is calculated.Patients (CEAP-class > C2) underwent venous duplex-ultrasound.419 limbs were investigated 298 (189 women 109 men); median age for men was 60 61 years, respectively; 32.2% had reflux residual-GSV;...
Aneurysm recurrence following coil occlusion is well recognized. However, there controversy as to how long these patients should be followed up after coiling detect reopening. We aimed identify the rate of late reopening and risk factors for in a large single-center cohort ruptured aneurysms that appeared adequately occluded at 6 months. also assess whether rates have altered over time with improving angiographic technology.Patients treated between 1996 2010 were assessed those both 6-month...
An unconscious 35-year-old man with a history of recreational drugs intake presented extremely distended and tympanic abdomen. Despite resuscitation, the patient was in shock. A CT scan thorax abdomen demonstrated extensive pneumoperitoneum that compressing viscera into central mass, which created an abdominal compartment-like syndrome. The inferior vena cava compressed decreased venous return to heart (figure 1). peritoneal gas extended mediastinum superiorly through oesophageal hiatus...
A 60-year-old man presented with a day’s history of sudden, spontaneous and severe swelling on the left side face neck. There was no trauma, surgery or radiotherapy. On examination, patient haemodynamically stable there discolouration tenderness over face. The mildly anaemic. An unenhanced CT scan head demonstrated large scalp haematoma in temporal region extending inferiorly (figure 1A). comparison MRI 1B) performed 2 years ago for epilepsy, revealed …
Most peripherally inserted central catheters (PICC-lines) in our institution are placed without real-time fluoroscopy. However, every patient has a completion chest radiograph, which is reported by radiologist to confirm the tip of PICC-line superior vena cava. Any deviation from desired position rectified. A 42-year-old woman had insertion her left arm. The radiograph demonstrated that was abnormally along mediastinal border (figure 1), contrary its normal course into cava right …
Erythropoietin (EPO) has tissue-protective properties, but it increases the risk of thromboembolism by raising haemoglobin concentration. New generation EPO derivatives is tissue protective without haematopoietic side effects. Preclinical studies have demonstrated their effectiveness and safety. This paper summarizes development in with emphasis on potential use critical limb ischaemia.
We present a rare case of short-segment jejunal infarction following inferior mesenteric artery embolisation for type 2 endoleak in patient who previously underwent endovascular repair abdominal aortic aneurysm. Potential causes the event might include thromboembolism or traumatic thrombosis branch superior (SMA) caused by buddy guide wire used to maintain position long vascular sheath SMA hiatus. The condition was recognised on CT and treated with resection infarcted segment small bowel...
A 50-year-old woman presented with non-specific abdominal pain. On examination, there was a firm palpable lump. CT of the abdomen demonstrated large nodular high attenuation poorly marginated intraperitoneal mass. The initial impression that patient might have had recent barium examination. As no such history, closer inspection scan multiformat reconstruction (figures 1⇓⇓–4) confirmed high-attenuation mass was, in fact, …
A 24-year-old woman presented with a swollen right leg and pulsatile lump in the popliteal fossa 3 days after diagnostic knee arthroscopy. The CT arteriogram demonstrated 6 cm pseudoaneurysm of artery (PA). There was early filling ipsilateral femoral vein contrast medium, indicating an abnormal communication between (figures 1 2). volume rendered three-dimensional reconstruction axial images further helped to localise exact site …