A5003756206- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Kawasaki Disease and Coronary Complications
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Coronary Artery Anomalies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Congenital Heart Disease Studies
- Cancer Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Medical Imaging and Pathology Studies
- Lanthanide and Transition Metal Complexes
- Viral Infections and Immunology Research
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Liver Disease and Transplantation
- Advanced Electron Microscopy Techniques and Applications
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Vitamin C and Antioxidants Research
- Circular RNAs in diseases
- Lysosomal Storage Disorders Research
Sichuan University
2011-2025
West China Second University Hospital of Sichuan University
2016-2025
Athinoula A. Martinos Center for Biomedical Imaging
2016
Harvard University
2016
Massachusetts General Hospital
2016
Atherosclerosis is a chronic inflammatory disease characterized by the formation of atherosclerotic plaques, while macrophages as key players in plaque progression and destabilization are promising targets for imaging. Contrast-enhanced magnetic resonance imaging (CE-MRI) has emerged powerful noninvasive technique evaluation plaques within arterial walls. However, visualization presents considerable challenges due to intricate pathophysiology dynamic behavior these cells. Biocompatible...
Background Increasing studies demonstrated that the cardiac involvements are related to coronavirus disease 2019 (COVID-19). Thus, we investigated clinical characteristics of patients with COVID-19 and further determined risk factors for involvement in them. Methods Results We analyzed data from 102 consecutive laboratory-confirmed hospitalized (52 women aged 19-87 years). Epidemiologic demographic characteristics, features, routine laboratory tests (including injury biomarkers),...
Abstract Background Since the outbreak of Coronavirus Disease 2019 (COVID-19) in China, respiratory manifestations disease have been observed. However, as a fatal comorbidity, acute myocardial injury (AMI) COVID-19 patients has not previously investigated detail. We clinical characteristics with AMI and determined risk factors for them. Methods analyzed data from 53 consecutive laboratory-confirmed hospitalized (28 men, 25 women; age, 19–81 years). collected information on epidemiological...
Chemical exchange saturation transfer (CEST) MRI is sensitive to dilute labile protons and microenvironmental properties, augmenting routine relaxation‐based MRI. Recent developments of quantitative CEST (qCEST) analysis such as omega plots RF‐power based ratiometric calculation have extended our ability elucidate the underlying system beyond simplistic apparent measurement. strongly varies with experimental factors, including RF irradiation level duration well repetition time flip angle. In...
Abstract Background Since December 2019, more than 100,000 coronavirus disease 2019 (COVID-19) patients have been confirmed globally based on positive viral nucleic acids with real-time reverse transcriptase-polymerase chain reaction (RT-PCR). However, the association between clinical, laboratory and CT characteristics RT-PCR results is still unclear. We sought to examine this in detail, especially recovered patients. Methods analysed data from 52 who had discharged COVID-19. The laboratory,...
Journal Article Accepted manuscript Cardiovascular magnetic resonance abnormalities in an infantile-onset Pompe Disease Get access Yaoji Zhu, Zhu Department of Radiology, Key Laboratory Birth Defects and Related Diseases Women Children Ministry Education, West China Second University Hospital, Sichuan University, No. 20, Section 3, Renmin South Road, Chengdu 610041, Search for other works by this author on: Oxford Academic PubMed Google Scholar Xiaoliang Liu, Liu Pediatric Cardiology,...
Kawasaki disease (KD) is an acute febrile illness and systemic vasculitis of unknown etiology that predominantly affects young children. The objective this study was to investigate the correlation between myocardial hepatic native T1 value late gadolinium enhancement (LGE) in pediatric patients with KD. In cross-sectional retrospective study, 115 KD (50 phase, 65 chronic phase) 40 age- gender-matched controls underwent cardiac magnetic resonance (CMR) imaging mapping LGE sequences. were...
Cardiovascular magnetic resonance (CMR) is crucial for the diagnosis and prognosis of heart disease. However, normal reference values CMR-derived morphology parameters have not been established Chinese children. We sought to establish ventricular atrial size function using CMR in healthy children across a broad age range. 3-T scans were performed 191 children, aged 4-18 years. used balanced steady-state free precession sequence analyzing chamber function. Reference percentile curves tables...
Purpose To determine whether 3.0-T magnetic resonance imaging (MRI) could assess right ventricular (RV) function in patients with hypertrophic cardiomyopathy (HCM), and if this assessment is correlated the New York Heart Function Assessment (NYHA) classification. Materials Methods Forty-six HCM 23 normal individuals were recruited. Left parameters including end-diastolic end-systolic volumes (EDV, ESV), stroke volume (SV) ejection fraction (EF) dimensions measured compared using MRI. RV...
Kawasaki disease (KD) potentially increases the risk of myocardial ischemia. This study aimed to semi-quantitatively evaluate perfusion impairment using cardiac magnetic resonance (CMR) first-pass in children with KD and explore association between coronary artery (CA) dilation perfusion.
Background: Despite an increase in the familiarity of medical community with epidemiological and clinical characteristics coronavirus disease 2019 (COVID-19), there is presently a lack rapid effective risk stratification indicators to predict poor outcomes COVID-19 especially severe patients. Methods: In this retrospective single-center study, we included 117 cases confirmed COVID-19. The clinical, laboratory, imaging features were collected analyzed during admission. Multi-lobular...
Diffusion kurtosis imaging (DKI) has been shown to augment diffusion‐weighted (DWI) for the definition of irreversible ischemic injury. However, complexity cerebral structure/composition makes map heterogeneous, limiting specificity hyperintensity acute ischemia. We propose an Inherent COrrelation‐based Normalization (ICON) analysis suppress intrinsic heterogeneity improved characterization heterogeneous tissue Fast DKI and relaxation measurements were performed on normal ( n = 10) stroke...
Coronary magnetic resonance angiography (CMRA) is being increasingly used in pediatric patients with congenital coronary artery anomalies (CAAs). However, the data on free-breathing self-navigation technique, which has potential to simplify acquisition plan a high success rate at 3T, remain scarce. This study investigated clinical application value of self-navigated (sNAV) CMRA 3T suspected CAAs and compared it conventional diaphragmatic-navigated (dNAV) CMRA.
Abstract Background Methylmalonic Aciduria and Homocystinemia, cobalamin C (cblC) is an inherited disease of vitamin B 12 metabolism with a wide spectrum clinical manifestations. cblC presenting pulmonary hypertension (PH) as leading sympotom rare easily misdiagnosed because limited awareness. Timely diagnosis crucial by the relentless progression without appropriate treatment. Case presentation We reported 12-year-old girl 3-year history progressively reduced activity tolerance 3-month...
Background Few studies assessed myocardial inflammation using Cardiovascular Magnetic Resonance Imaging in Kawasaki disease (KD) patients. Purpose To quantify edema KD patients T2 mapping and explore the independent predictors of values. Study Type Prospective. Subjects Ninety including 40 acute phase (26 males, 65.0%) 50 chronic (34 68.0%). Thirty‐one healthy volunteers (21 70.0%). Field Strength/Sequence 3.0 T T2‐weighted Turbo Spin Echo‐Short Time Inversion Recovery sequence, True fast...
We developed a novel manganese (Mn 2+ ) chelate for magnetic resonance imaging (MRI) assessment of myocardial viability in acute and chronic infarct (MI) models, compared it with Gadolinium‐based delay enhancement MRI (Gd 3+ ‐DEMRI) histology. MI was induced 14 rabbits by permanent occlusion the left circumflex coronary artery. Gd ‐DEMRI Mn chelate‐based delayed chelate‐DEMRI) were performed at 7 days (acute MI, n = 8) or 8 weeks (chronic 6) after surgery sequential injection 0.15 mmol/kg...