A5039739893- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrest and Resuscitation
- Pancreatic and Hepatic Oncology Research
- Innovations in Medical Education
- Lipid metabolism and disorders
- Spinal Cord Injury Research
- Chronic Disease Management Strategies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Coronary Interventions and Diagnostics
- Clinical Reasoning and Diagnostic Skills
- Systemic Lupus Erythematosus Research
- Acute Kidney Injury Research
- High Altitude and Hypoxia
- Blood Pressure and Hypertension Studies
- Surgical Sutures and Adhesives
- Meta-analysis and systematic reviews
- Environmental Justice and Health Disparities
- Medication Adherence and Compliance
- Air Quality and Health Impacts
- Orthopedic Surgery and Rehabilitation
- Peripheral Neuropathies and Disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
Mayo Clinic in Florida
2017-2025
Mayo Clinic
2013-2025
Mayo Clinic in Arizona
2012-2024
University of Minnesota Rochester
2020-2021
WinnMed
2012-2020
University of Saint Mary
2012
Background: The epidemiology of osteomyelitis in the United States is largely unknown. purpose this study was to determine long-term secular trends incidence a population-based setting. Methods: population comprised 760 incident cases first diagnosed between January 1, 1969, and December 31, 2009, among residents Olmsted County, Minnesota. complete medical records for each potential subject were reviewed confirm diagnosis extract details on anatomical sites, infecting organisms, etiological...
Podocyturia, the shedding of live podocytes, is present at delivery in women with preeclampsia. The aim this study was to test whether podocyturia earlier pregnancy and predicts for We also aimed compare characteristics those angiogenic factors previously implicated pathogenesis disorder. prospectively enrolled 315 who provided blood urine samples end second trimesters their pregnancies (median, 27 gestational weeks) within 24 hours deliveries 39.5 weeks). Blood were analyzed markers,...
Importance US rural vs nonrural populations have striking disparities in diabetes care. Whether rurality contributes to mortality is unknown. Objective To examine rates and trends based on county urbanization. Design, Setting, Participants In this observational, cross-sectional study, the Centers for Disease Control Prevention Wide-Ranging Online Data Epidemiologic Research database was searched from January 1, 1999, December 31, 2018, as a multiple cause underlying of death among residents...
Platelet transmission electron microscopy (PTEM) is considered the gold standard test for assessing distinct ultrastructural abnormalities in inherited platelet disorders (IPDs). Nevertheless, PTEM remains mainly a research tool due to lack of standardized procedures, validated dense granule (DG) count reference range, and image interpretation criteria. The aim this study was standardize validate as clinical laboratory test. Based on previously established methods, we optimized...
Abstract Severe hypercholesterolemia/possible familial hypercholesterolemia (FH) is relatively common but underdiagnosed and undertreated. We investigated whether implementing clinical decision support (CDS) was associated with lower low-density lipoprotein cholesterol (LDL-C) in patients severe FH (LDL-C ≥ 190 mg/dL). As part of a pre-post implementation study, CDS alert deployed the electronic health record (EHR) large system comprising 3 main sites, 16 hospitals 53 clinics. Data were...
Importance Understanding the interplay between diabetes risk factors and development is important to develop individual, practice, population-level prevention strategies. Objective To evaluate progression from normal impaired fasting glucose levels among adults. Design, Setting, Participants This retrospective community-based cohort study used data Rochester Epidemiology Project, in Olmsted County, Minnesota, on 44 992 individuals with at least 2 plasma (FPG) measurements January 1, 2005,...
Background Hypertriglyceridemia is associated with increased risk of coronary heart disease but the association often attributed to concomitant metabolic abnormalities. We investigated epidemiology primary isolated hypertriglyceridemia (PIH) and cardiovascular in a population-based setting. Methods Results identified adults at least one triglyceride level ≥500 mg/dL between 1998 2015 Olmsted County, Minnesota. also age- sex-matched controls levels <150 mg/dL. There were 3329 individuals...
Abstract Background The aim of this study was to evaluate the use a glucose meter with surgical patients under general anesthesia in operating room. Methods Glucose measurements were performed intraoperatively on 368 paired capillary and arterial whole blood samples using Nova StatStrip (Nova Biomedical, USA) compared reference by gas analyzer 196 patients. Primary outcomes median bias (meter minus reference), percentage meeting accuracy criteria for subcutaneous insulin dosing as defined...
Abstract Background Dyad learning has been shown to be an effective tool for teaching procedural skills, but little is known about how dyad may impact the stress, anxiety, and cognitive load that a student experiences when in this manner. In pilot study, we investigate relationship between training on load, performance simulated bradycardia scenario. Methods Forty-one fourth-year medical school trainees were randomized as dyads ( n = 24) or individuals 17) education session day 1....
To analyze consistency of reference limits and widths intervals (RIs) calculated by six procedures evaluate a protocol for merging intrainstitutional data.The differences between were compared with "optimal" bias goals. Also, the RIs compared. using Mayo-SAS quantile, EP Evaluator, four International Federation Clinical Chemistry Laboratory Medicine methods: parametric nonparametric (NP) without latent abnormal values exclusion (LAVE). Regression parameters from cotested samples evaluated...
Anderson, Paul J., Christina M. Wood-Wentz, Kent R. Bailey, and Bruce D. Johnson. Objective versus self-reported sleep quality at high altitude. High Alt Med Biol. 24:144-148, 2023. Background: Previous studies have found little relationship between polysomnography a diagnosis of acute mountain sickness (AMS) using the Lake Louise Symptom Questionnaire (LLSQ). The correlation question responses on LLSQ results has not been explored. We compared data from our previous study workers rapidly...
Background: Medication use in the intensive care unit (ICU) depends on creatinine-based glomerular filtration rate (GFR) estimates. Urine output deterioration may precede creatinine rise resulting delayed recognition of GFR reductions. Our objective was to quantify disparity between estimated (eGFR) and true ICU patients with hospital-acquired oligoanuric acute kidney injury (hAKI). Methods: This single-center cohort study examined adults who met Acute Kidney Injury Network stage III urine...
Abstract Background Customized and standard automated insulin delivery (AID) systems for use in pregnancies of women with preexisting type 1 diabetes (T1D) are being developed tested to achieve pregnancy appropriate continuous glucose monitoring (CGM) targets. Guidance on the CGM treatment decisions during United States is limited. Methods Ten pregnant T1D participated a trial evaluating at-home pregnancy-specific AID system. Seven-point self-monitoring blood (SMBG) was compared closest...
Background Automated external defibrillators can provide life‐saving therapies to treat ventricular fibrillation. We developed a prototype unit that deliver unique shock waveform produced by four independent capacitors is delivered through two vectors, with the rationale of providing more robust pathways during emergent defibrillation. describe initial testing and feasibility this defibrillation unit, features which may enable downsizing current defibrillator devices. Methods tested our in...
Expression of prostaglandin biosynthetic pathway enzymes in mucinous pancreatic cysts is unknown. Cyclooxygenase-2 (COX-2) inhibition a potential cancer chemoprevention strategy for these lesions. We evaluated the expression COX-2, cytosolic phospholipase A2 (cPLA2), and protein kinase B (AKT) epithelium correlated enzyme with aspirin (ASA) use cyst fluid E2 (PGE2) concentration.Pathology 80 resected was reviewed. cPLA2, AKT quantified by tissue immunohistochemistry immunoreactivity scores...