- Migraine and Headache Studies
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Trigeminal Neuralgia and Treatments
- Color perception and design
- Atrial Fibrillation Management and Outcomes
- Ophthalmology and Eye Disorders
- Diabetes Treatment and Management
- Heart Failure Treatment and Management
- Sympathectomy and Hyperhidrosis Treatments
- Health, Medicine and Society
- Healthcare Systems and Practices
- Color Science and Applications
- Olfactory and Sensory Function Studies
- Lipoproteins and Cardiovascular Health
- Coronary Interventions and Diagnostics
- Acute Ischemic Stroke Management
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
- Opioid Use Disorder Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
Hôpital Lariboisière
2013-2025
University of Leeds
2018-2023
Université Paris Cité
1990-2022
Inserm
1990-2022
Hôpital Cochin
2022
Assistance Publique – Hôpitaux de Paris
2010-2022
Hôpital Européen Georges-Pompidou
2019-2022
Université Paris-Est Créteil
2022
Hôpital Pontchaillou
2022
Hôpitaux Universitaires Henri-Mondor
2022
Abstract Aims Out-of-hospital cardiac arrest (OHCA) without return of spontaneous circulation (ROSC) despite conventional resuscitation is common and has poor outcomes. Adding extracorporeal membrane oxygenation (ECMO) to cardiopulmonary (extracorporeal-CPR) increasingly used in an attempt improve Methods results We analysed a prospective registry 13 191 OHCAs the Paris region from May 2011 January 2018. compared survival at hospital discharge with extracorporeal-CPR identified factors...
To determine the prevalence and clinical features of migraine related headache types in France.The authors recruited a population subjects with representative national using stratified sampling method. They screened 10,585 aged 15 older who were general population. identified 1,486 these as having headaches, subsequently interviewed for information on features, natural history, functional impact headache. The categorized based International Headache Society (IHS) classification assessed...
We set out to study the role of psychiatric comorbidity in evolution migraine medication overuse headache (MOH) by a comparative 41 migraineurs (MIG) and patients suffering from MOH deriving migraine. There was an excess risk mood disorders [odds ratio (OR) = 4.5, 95% confidence interval (CI) 1.5, 13.5], anxiety (OR 5, CI 1.2, 10.7) associated with use psychoactive substances other than analgesics 7.6, 2.2, 26.0) compared MIG. Retrospective order occurrence showed that group, occurred...
Prospective studies of precipitating factors in migraine are rare. Mig Access is a national control‐matched survey conducted to evaluate the access migraineurs health care France. This study allowed us screen prospectively some headache and nonmigraineurs. Three hundred eighty‐five (group 1) 313 nonmigraineurs 2) kept diary for 3‐month period (a total 35 805 days group 1 29 109 2). Precipitating were reported each period. Headache intensity was self‐assessed during using visual analog scale...
We investigated the prevalence of Parkinson's disease in a representative sample elderly population living Gironde département, France. Among 3149 people over age 65, ratio for was 1.4%, without significant difference between men and women. found that age-specific ratios increased with from 0.5% group 65 to 69 6.1% individuals 90. This pattern is consistent other population-based studies. Interestingly, slope similar previously reported Lewy bodies. Our study showed high proportion (42%)...
To assess the burden of migraine, we compared productivity and perceived health 991 migraine sufferers (IHS criteria), 1004 other‐headache sufferers, 1757 nonheadache randomly chosen among volunteers from employees French national gas electricity company. The extent absenteeism was collected independently study subjects during a 4‐year period. Performance at work self‐assessed end followup. also completed Short‐Form 36 Health Survey Questionnaire (SF36) Spielberger anxiety scale. number...
To assess the global impact of episodic headaches in patients consulting general practitioners (GPs) using Headache Impact Test (HIT‐6) questionnaire, and to compare this with measures headache severity quality life. A total 2802 349 GPs participated cross‐sectional study. Data were collected on Migraine Severity (MIGSEV) scale, HIT‐6 life Qualité de Vie et (QVM) questionnaire. Diagnosis was assigned retrospectively according International Society criteria. The association between scale...
We analysed the possible protective role of human endothelial (EPCs) and smooth muscle (SPCs) progenitor cells on atherosclerosis development in apoE(-/-)RAG2(-/-) mice. determined plasma levels SPCs coronary patients.ApoE(-/-)RAG2(-/-) mice received four intravenous injections saline, 5 x 10(5) SPCs, or EPCs every other week, one (preventive approach) 12(curative weeks after starting a high fat diet. Derived-SPC were quantified from blood mononuclear patients with stable angina (n = 10)...
Swallowing disorders are common in Parkinson's disease but of obscure and complex nature pathophysiology. The effect central dopaminergic stimulation on disordered swallowing is not well known. We studied the effects apomorphine (in combination with domperidone) buccolinguofacial motoricity various stages by using videofluoroscopy eight patients dysphagia. abnormalities more frequently encountered were vallecular stasis (n = 7), fragmentation bolus buccal stagnation bolus. Apomorphine...
The authors recently reexamined the peripheral nerve biopsies from 42 patients with chronic inflammatory demyelinating polyneuropathy (CIDP). There were 27 males and 15 females, aged 9 to 84 years, 13 had relapses. No patient vasculitis, monoclonal gammopathy, tumor, diabetes mellitus, Lyme disease, familial neuropathy, HIV, or any other immune deficiency. In endoneurium, perivascular cell infiltrates present in only one case, but scattered histiocytes marked by KP1 on paraffin-embedded...
1. The effect of protein kinase activators on cloned inward rectifier channels expressed in Xenopus oocytes was examined using a two‐electrode voltage clamp. PKA caused no change KIR1.1, KIR2.1, or KIR2.3 current. PKC phorbol 12‐myristate 14‐acetate (PMA) and 12, 13‐dibutyrate (PDBu) inhibited currents, but not KIR2.1 KIR1.1 This inhibition blocked by staurosporine. An inactive ester, 4 alpha‐phorbol 13‐didecanoate (4 alpha‐PDD), had KIR2.3. 2. Upon changing solution from 2 to 98 microM K+,...
Abstract Background Although the presence and extent of ischaemic late gadolinium enhancement (LGE) as assessed by cardiovascular magnetic resonance (CMR) have emerged robust predictors outcomes in patients with cardiomyopathy (ICM), prognostic significance non-ischaemic LGE is not well established. Objective To assess impact a large cohort ICM reduced left ventricular ejection fraction (LVEF) undergoing CMR for myocardial viability. Methods Between 2008 2022, all consecutive referred...
Certain nonsteroidal anti-inflammatory drugs are effective in the acute treatment of migraine attacks. The authors report a double-blind, placebo-controlled, randomized cross-over trial dual-release formulation oral ketoprofen attacks.The compared efficacy two doses (75 or 150 mg) with that placebo (primary analysis) and zolmitriptan 2.5 mg (secondary on one to four consecutive attacks 235 intent-to-treat patients (out 257 patients) without aura. principal outcome was headache relief...