A5064129181- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Quantum Dots Synthesis And Properties
- RNA Interference and Gene Delivery
- Magnetic Properties and Synthesis of Ferrites
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticles: synthesis and applications
- Graphene research and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Conducting polymers and applications
- Curcumin's Biomedical Applications
- Bone Tissue Engineering Materials
- Carbon and Quantum Dots Applications
- Magnetic properties of thin films
- Carbon Nanotubes in Composites
- Multiferroics and related materials
- Characterization and Applications of Magnetic Nanoparticles
- Advanced Sensor and Energy Harvesting Materials
- Molecular Junctions and Nanostructures
- Seaweed-derived Bioactive Compounds
- Analytical Chemistry and Sensors
- Magneto-Optical Properties and Applications
- Supramolecular Self-Assembly in Materials
Bharat Heavy Electricals (India)
2024
Toyo University
2014-2023
University of Arizona Cancer Center
2023
University of Arizona
2022-2023
University of Wisconsin–Madison
2023
Indian Institute of Technology Hyderabad
2023
University of South Australia
2022
Saitama Prefecture
2011-2018
Graduate School USA
2015-2017
Kawagoe Technical High School
2015-2017
Alzheimer's disease is a growing concern in the modern world. As currently available medications are not very promising, there an increased need for fabrication of newer drugs. Curcumin plant derived compound which has potential activities beneficial treatment disease. Anti-amyloid activity and anti-oxidant curcumin highly The insolubility water restricts its use to great extend, can be overcome by synthesis nanoparticles. In our work, we have successfully synthesized water-soluble PLGA...
Nanoparticles of manganese ferrite were prepared by the chemical co-precipitation technique. The dielectric parameters, namely, real and imaginary permittivity (ε' ε''), ac conductivity (σac) loss tangent (tanδ), measured in frequency range 100 kHz–8 MHz at different temperatures. variations dispersion (ε') absorption (ε'') with temperature also investigated. variation followed Maxwell–Wagner model based on interfacial polarization consonance Koops phenomenological theory. hence ε''...
Liposomes and polymers are widely used drug carriers for controlled release since they offer many advantages like increased treatment effectiveness, reduced toxicity of biodegradable nature. In this work, anticancer drug-loaded PLGA-lecithin-PEG nanoparticles (NPs) were synthesized functionalized with AS1411 anti-nucleolin aptamers site-specific targeting against tumor cells which over expresses nucleolin receptors. The particles characterized by transmission electron microscope (TEM) X-ray...
Nanomedicine utilizes engineered nanodevices and nanostructures for monitoring, repair, construction control of human biological systems at the molecular level. In this study, we investigated feasibility potential zein nanofiber as a delivery vehicle curcumin in biomedical applications. By optimizing electrospinning parameters, ultrafine fluorescence nanofibers containing were developed with interconnected fibrous networks. We found that these show an increase due to incorporation curcumin....
Fluorinated graphene oxide (FGO) is reported for the first time as a magnetically responsive drug carrier that can serve both magnetic resonance imaging (MRI) and photoacoustic contrast agent, under preclinical settings, type of photothermal therapy. Its hydrophilic nature facilitates biocompatibility. FGO broad wavelength absorber, with high charge transfer strong non-linear scattering optimal NIR laser-induced hyperthermia.
Details of a fast and sustainable bottom-up process to grow large area high quality graphene films without the aid any catalyst are reported in this paper. We used Melaleuca alternifolia, volatile natural extract from tea tree plant as precursor. The as-fabricated yielded stable contact angle 135°, indicating their potential application very hydrophobic coatings. electronic devices formed by sandwiching pentacene between aluminum demonstrated memristive behavior, hence, these could find use...
For the successful diverse applications of different nanomaterials in life sciences, it is necessary to understand ultimate fate, distribution and potential environmental impacts manufactured nanomaterials. Phytotoxicity studies using higher plants an important criterion for understanding toxicity engineered We studied effects carbon various dimensionalities (carbon nanotubes, C60, graphene) on germination rice seeds. A pronounced increase rate was observed seeds presence some these...
Nonspecificity and cardiotoxicity are the primary limitations of current doxorubicin chemotherapy. To minimize side effects to enhance bioavailability cancer cells, a dual-targeted pH-sensitive biocompatible polymeric nanosystem was designed developed. An ATRP-based biodegradable triblock copolymer, poly(poly(ethylene glycol) methacrylate)-poly(caprolactone)-poly(poly(ethylene methacrylate) (pPEGMA-PCL-pPEGMA), conjugated with via an acid-labile hydrazone bond synthesized characterized. Dual...
Abstract: The efficient targeting and therapeutic efficacy of a combination drugs (curcumin 5-Fluorouracil [5FU]) magnetic nanoparticles encapsulated poly(D,L-lactic-co-glycolic acid) nanoparticles, functionalized with two cancer-specific ligands are discussed in our work. This multifunctional, highly specific nanoconjugate resulted the superior uptake by cancer cells. Upon hyperthermia, we could harness advantages incorporating that synergistically acted to destroy cells within very short...
Abstract: The photothermal effect of single-walled carbon nanotubes (SWCNTs) in combination with the anticancer drug doxorubicin (DOX) for targeting and accelerated destruction breast cancer cells is demonstrated this paper. A targeted drug-delivery system was developed selective killing polyethylene glycol biofunctionalized DOX-loaded SWCNTs conjugated folic acid. In our work, vitro drug-release studies showed that binds at physiological pH (pH 7.4) released only a lower pH, ie, lysosomal...
A multifunctional biocompatible nanovector based on magnetic nanoparticle and carboxymethyl cellulose (CMC) was developed. The nanoparticles have been characterized using TEM, SEM, DLS, FT-IR spectra, VSM, TGA studies. We found that the synthesized (CMC MNPs) were spherical in shape with an average size of 150 nm having low aggregation superparamagnetic properties. folate-tagged CMC MNPs delivered to cancer cells by a folate-receptor-mediated endocytosis mechanism. 5-FU encapsulated as model...