A5007722411- Rabies epidemiology and control
- Bat Biology and Ecology Studies
- Yersinia bacterium, plague, ectoparasites research
- Bacillus and Francisella bacterial research
- Zoonotic diseases and public health
- Virology and Viral Diseases
- Viral Infections and Vectors
- Influenza Virus Research Studies
- Poxvirus research and outbreaks
- Insect and Pesticide Research
- Viral Infections and Outbreaks Research
- Meat and Animal Product Quality
- Brucella: diagnosis, epidemiology, treatment
- Animal Ecology and Behavior Studies
- Toxin Mechanisms and Immunotoxins
Universidad Peruana Cayetano Heredia
2022-2025
Asociación para la Conservación de la Cuenca Amazónica
2025
Association for Research and Industrial Development of Natural Resources
2024
CONAPAC
2020
Universitat Autònoma de Barcelona
2020
Ministry of Health
2012
Despite extensive culling of common vampire bats in Latin America, lethal human rabies outbreaks transmitted by this species are increasingly recognized, and livestock occurs with striking frequency. To identify the individual population-level factors driving virus (RV) transmission bats, we conducted a longitudinal capture–recapture study 20 bat colonies spanning four regions Peru. Serology demonstrated circulation RV from all years. Seroprevalence ranged 3 to 28 per cent was highest...
Significance In Latin America, vampire bat rabies constrains livestock production and is the main cause of lethal human outbreaks. Despite knowledge that dispersal prevents viral extinction compromises control campaigns, movement patterns infected bats are unknown. Using large host virus datasets, we illustrate a genetic approach to link population level pathogen spatial spread overcomes logistical limitations tracking animal in wild. The results implicate male as contributing...
Controlling pathogen circulation in wildlife reservoirs is notoriously challenging. In Latin America, vampire bats have been culled for decades hopes of mitigating lethal rabies infections humans and livestock. Whether culls reduce or exacerbate transmission remains controversial. Using Bayesian state-space models, we show that a 2-year, spatially extensive bat cull an area exceptional incidence Peru failed to spillover livestock, despite reducing population density. Viral whole genome...
A major obstacle to anticipating the cross-species transmission of zoonotic diseases and developing novel strategies for their control is scarcity data informing how these pathogens circulate within natural reservoir populations. Vampire bats are primary rabies in Latin America, where disease remains among most important viral zoonoses affecting humans livestock. Unpredictable spatiotemporal dynamics bat populations have precluded anticipation outbreaks undermined widespread culling...
Background Knowledge of infectious disease burden is necessary to appropriately allocate resources for prevention and control. In Latin America, rabies among the most important zoonoses human health agriculture, but attributed its main reservoir, common vampire bat (Desmodus rotundus), remains uncertain. Methodology/Principal findings We used questionnaires quantify under-reporting livestock deaths across 40 agricultural communities with differing access epidemiological histories (VBR) in...
The pathogen transmission dynamics in bat reservoirs underpin efforts to reduce risks human health and enhance conservation, but are notoriously challenging resolve. For vampire rabies, the geographical scale of enzootic cycles, whether environmental factors modulate baseline risk, how within-host processes affect population-level remain unresolved. We studied patterns rabies exposure using an 11-year, spatially replicated sero-survey 3709 Peruvian bats co-occurring outbreaks livestock....
1. Human activities can alter animal movement, having unexpected consequences for disease transmission. In Latin America, culls of common vampire bats ( Desmodus rotundus ) rabies control have been indicated to raise viral spatial spread by increasing long-range movement and inter-colony mixing among surviving bats, but behavioural responses disturbance not quantified. 2. We used Global Positioning System (GPS) tags track the movements 93 from 5 roosts in Peruvian Andes over 9 nights after...
Interrupting pathogen transmission between species is a priority strategy to mitigate zoonotic threats. However, avoiding counterproductive interventions requires knowing animal reservoirs of infection and the dynamics within them, neither which are easily ascertained from cross-sectional surveys that now dominate investigations into newly discovered viruses. We used biobanked sera metagenomic data reconstruct recently bat-associated influenza virus (BIV; H18N11) over 12 years in three zones...
Predicting the spatial occurrence of wildlife is a major challenge for ecology and management. In Latin America, limited knowledge number locations vampire bat roosts precludes informed allocation measures intended to prevent rabies spillover humans livestock. We inferred distribution while accounting observation effort environmental effects by fitting log Gaussian Cox process model 563 in three regions Peru. Our explained 45% variance observed roost identified drivers establishment. When...
Abstract Predicting the spatial occurrence of wildlife is a major challenge for ecology and management. In Latin America, knowledge true number locations vampire bat colonies precludes informed allocation measures intended to limit lethal rabies spillover humans livestock. We inferred complete distribution roosts while accounting observation effort environmental covariates by fitting Log Gaussian Cox Process model 563 in three regions Peru. Our explained 47% variance observed roost...
Abstract Interrupting pathogen transmission between species is a priority strategy to mitigate zoonotic threats. However, avoiding counterproductive interventions requires knowing animal reservoirs of infection and the dynamics within them, neither which are easily ascertained from cross-sectional surveys currently dominate investigations into newly discovered viruses. We used biobanked sera metagenomic data reconstruct recently bat-associated influenza virus (BIV) over 12 years in three...