A5020663042- Traumatic Brain Injury Research
- Neural and Behavioral Psychology Studies
- Psychology of Moral and Emotional Judgment
- Action Observation and Synchronization
- Traumatic Brain Injury and Neurovascular Disturbances
- Memory and Neural Mechanisms
- Attachment and Relationship Dynamics
- Spatial Neglect and Hemispheric Dysfunction
- Deception detection and forensic psychology
- Functional Brain Connectivity Studies
- Dementia and Cognitive Impairment Research
- Social and Intergroup Psychology
- Psychosomatic Disorders and Their Treatments
- Face Recognition and Perception
- Child and Adolescent Psychosocial and Emotional Development
- Neuroendocrine regulation and behavior
- Motor Control and Adaptation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neurobiology of Language and Bilingualism
- Psychological Well-being and Life Satisfaction
- Racial and Ethnic Identity Research
- Cognitive Functions and Memory
- Digital Communication and Language
- Health disparities and outcomes
- Evolutionary Psychology and Human Behavior
National Institute of Neurological Disorders and Stroke
2012-2024
National Institute of Mental Health
2009-2021
Wright-Patterson Air Force Base
2021
National Institutes of Health
2008-2020
Centre National de la Recherche Scientifique
2015
University of Turin
2015
Université Claude Bernard Lyon 1
2015
Centre de Recherche en Neurosciences de Lyon
2015
Inserm
2015
University of Wisconsin–Eau Claire
2014
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype poorly defined, pathophysiology unknown, and no disease-modifying treatments are available. We used rigorous criteria to recruit PI-ME/CFS participants with matched controls conduct deep phenotyping. Among many physical cognitive complaints, one defining feature of was an alteration effort preference, rather than or central fatigue, due dysfunction integrative...
Abstract Functional MRI was used to identify the brain areas underlying automatic beliefs about gender and race, suppression of those attitudes. Participants ( n = 20; 7 females) were scanned at 3 tesla while performing Implicit Association Test (IAT), an indirect measure race bias. We hypothesized that ventromedial prefrontal cortex (PFC) would mediate racial stereotypic attitudes, these recruit dorsolateral (DLPFC) anterior cingulate (ACC). Performance data on IAT revealed biases. Racial...
Abstract We assessed political attitudes using the Implicit Association Test (IAT) in which participants were presented with faces and names of well-known Democrat Republican politicians along positive negative words while undergoing functional MRI. found a significant behavioral IAT effect for face, but not name, condition. The fMRI face condition results indicated that ventromedial anterior prefrontal cortices activated during attitude inducement. Amygdala fusiform gyrus perceptual...
The ability to read emotions in the face of another person is an important social skill that can be impaired subjects with traumatic brain injury (TBI). To determine regions modulate facial emotion recognition, we conducted a whole-brain analysis using well-validated recognition task and voxel-based lesion symptom mapping (VLSM) large sample patients focal penetrating TBIs (pTBIs). Our results revealed individuals pTBI performed significantly worse than normal controls recognizing unpleasant...
Disinhibition, the inability to inhibit inappropriate behavior, is seen in frontal-temporal degeneration, Alzheimer's disease, and stroke. Behavioral disinhibition leads social emotional impairments, including impulsive behavior disregard for conventions. The authors investigated effects of lesions on behavioral measured by Neuropsychiatric Inventory 177 veterans with traumatic brain injuries. performed voxel-based lesion-symptom mapping using MEDx. Damage frontal temporal lobes, gyrus...
Moral judgment is an evaluation of the actions and character a person made with respect to societal norms. Although many types vignettes have been used in previous studies on moral beliefs judgment, what missing set standardized common based real life. The goal this study was provide researchers stimuli that values several dimensions pertaining whose underlying components are known. These will allow select ratings rather than results pilot studies, while avoiding limitations classic,...
Apathy, common in neurological disorders, is defined as disinterest and loss of motivation, with a reduction self‐initiated activity. Research diseased populations has shown that apathy associated variations the volume brain regions such anterior cingulate frontal lobes. The goal this study was to determine neural signatures people penetrating traumatic injuries (pTBIs), our knowledge, these have not been studied sample. We 176 male Vietnam War veterans pTBIs using voxel‐based lesion‐symptom...
Third-party punishment (TPP) for norm violations is an essential deterrent in large-scale human societies, and builds on two cognitive functions: evaluating legal responsibility determining appropriate punishment. Despite converging evidence that TPP mediated by a specific set of brain regions, little known about their effective connectivity (direction strength connections). Applying parametric event-related functional MRI conjunction with multivariate Granger causality analysis, we asked...
<i>Background:</i> Patients with syndromes of the frontotemporal dementia spectrum are frequently unaware their behavioral changes. <i>Methods:</i> Seventy patients a clinical diagnosis variant (bv-FTD, n = 27), aphasic (a-FTD, 12) and corticobasal syndrome (CBS, 31) participated in study. Anosognosia for disturbances was measured as discrepancy between caregiver’s patient’s ratings on Frontal Systems Behavior Scale <i>present</i>...
Aggressive behavior is common during adolescence. Although aggression-related functional changes in the ventromedial prefrontal cortex (vmPFC) and frontopolar (FPC) have been reported adults, neural correlates of aggressive adolescents, particularly context structural neurodevelopment, are obscure. We used magnetic resonance imaging (MRI) to measure blood oxygenation level-depended signal cortical thickness. In a block-designed experiment, 14–17-year old adolescents imagined non-aggressive...
Theory of mind (ToM), the capacity to infer intention, beliefs and emotional states others, is frequently impaired in behavioural variant fronto-temporal dementia patients (bv-FTDp); however, its impact on caregiver burden unexplored.National Institute Neurological Disorders Stroke, National Institutes Health.bv-FTDp (n = 28), a subgroup their caregivers 20) healthy controls 32).we applied faux-pas (FP) task as ToM measure bv-FTDp Zarit Burden Interview patients' caregivers. Patients...
Individuals differ in the extent to which they make decisions different moral dilemmas. In this study, we investigated relationship between functional brain activities during decision making and psychopathic personality traits a healthy population. We measured hemodynamic of by near-infrared spectroscopy (fNIRS). FNIRS is an evolving non-invasive neuroimaging modality relatively inexpensive, patient friendly robust subject movement. Psychopathic were evaluated through self-report...
To investigate the association between traumatic brain injury (TBI)-related lesions and long-term caregiver burden in relation to dysexecutive syndrome.National Institute of Neurological Disorders Stroke, National Institutes Health, Bethesda, Maryland.A total 256 participants: 105 combat veterans with TBI, 23 healthy control (HCv), 128 caregivers.Caregiver assessed by Zarit Burden Interview at 40 years postinjury.Participants penetrating TBI were compared HCv on perceived neuropsychological...
Abstract Background Understanding the neural basis of moral judgment (MJ) and human decision‐making has been subject numerous studies because their impact on daily life activities social norms. Here, we aimed to investigate process MJ using functional near‐infrared spectroscopy (fNIRS), a noninvasive, portable, affordable neuroimaging modality. Methods We examined prefrontal cortex (PFC) activation in 33 healthy participants engaging exercises. hypothesized that presented with personal...
To determine areas of atrophy in patients that are associated with caregiver burden.We measured burden, dementia and neuropsychiatric scores 22 corticobasal syndrome (CBS) 25 frontotemporal (FTD), 14 healthy controls. We used voxel-based morphometry to correlate burden gray matter loss.Increased behavioral disturbances contributed higher CBS patients, while alone significantly affected frontal-variant FTD (FTD-fv) patients. In correlated left inferior middle temporal gyri.Caregivers FTD-fv...
To examine whether a caregiver's attachment style is associated with patient cognitive trajectory after traumatic brain injury (TBI).National Institute of Neurological Disorders and Stroke, National Institutes Health, Bethesda, Maryland.Forty Vietnam War veterans TBI their caregivers.Cognitive performance, measured by the Armed Forces Qualification Test percentile score, completed at 2 time points: preinjury 40 years postinjury.On basis caregivers' (secure, fearful, preoccupied, dismissing),...
Grounded in Olson's Circumplex Model of Marital and Family Systems (1993), the associations between family disengagement, different sources social support, loneliness, stress for young adults were examined. Data collected from 241 college students at three time points: semester week 2, 8, 14. Results indicated that experienced increased levels disengagement as progressed. Furthermore, a serial multiple mediation analysis T1 T3 could be explained by perceptions less greater stress. Finally,...