A5041485700- Bone health and osteoporosis research
- Photonic and Optical Devices
- Bone fractures and treatments
- Bone Tissue Engineering Materials
- Advancements in Semiconductor Devices and Circuit Design
- Bone and Joint Diseases
- Semiconductor Quantum Structures and Devices
- Laser Applications in Dentistry and Medicine
- Nanowire Synthesis and Applications
- Semiconductor materials and devices
- Osteoarthritis Treatment and Mechanisms
- Dental Implant Techniques and Outcomes
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Bone health and treatments
- Knee injuries and reconstruction techniques
- Laser Material Processing Techniques
- Semiconductor Lasers and Optical Devices
- Animal Nutrition and Physiology
- Silicon Nanostructures and Photoluminescence
- X-ray Spectroscopy and Fluorescence Analysis
- Protease and Inhibitor Mechanisms
- Connective tissue disorders research
- Titanium Alloys Microstructure and Properties
- Nuclear Physics and Applications
McMaster University
2010-2023
Brockhouse Institute for Materials Research
2023
Washington University in St. Louis
2008-2012
University of Wisconsin–Madison
2011
University of Calgary
1997-2007
Barnes-Jewish Hospital
2006-2007
University of Stuttgart
1993-2006
University of Alberta
2004
Leibniz Institute for High Performance Microelectronics
1991
Institute of Semiconductors
1991
Vertical-incidence Germanium photodiodes grown on thin strain-relaxed buffers Silicon substrates are reported. For a mesa-type detector with diameter of 10 μm, resistance-capacitance-limited 3-dB bandwidth 25.1 GHz at an incident wavelength 1552 nm and zero external bias has been measured. At reverse 2 V, the is 38.9 GHz. The comprises 300-nm-thick intrinsic region, thus, potential for easy integration Si circuitry exhibits quantum efficiencies 23%, 16%, 2.8% 850, 1298, nm, respectively.
Creatine kinase, found in osteoblasts, is an enzyme that upregulated response to interventions enhance bone mass accretion. monohydrate supplementation can increase fat-free young healthy men and women reduce markers of breakdown boys with Duchenne muscular dystrophy.The objective this study was determine the influence creatine on structure function growing rats, establish a therapeutic model.Creatine (2% w.w.) (CR; N = 16) or standard rat chow (CON; fed Sprague-Dawley rats beginning at 5 wk...
Polydimethylsiloxane (PDMS) and parylene are among the most widely used polymers in biomedical microfluidic applications due to their favorable properties. Due differences chemical structure fabrication methods, it is difficult integrate them together on a single device. In this paper, we have demonstrated method bond patterned PDMS with without use of high temperature or pressure two-step process. The steps include (1) attachment cured surface using microcontact printing form weak followed...
Ultrashort pulsed lasers in bone ablation show promise for many orthopedic applications. To minimize collateral tissue damage and control the process, threshold fluence must be well characterized. Using an amplified femtosecond laser (170 fs, 800 nm, 1 kHz), on unaltered porcine cortical was measured using D2 method at multiple incident pulse numbers ranging from 25 to 1000 pulses per spot. The lowered greater indicated incubation effect. a power law model, coefficient of found 0.89 ± 0.03....
Abstract The purpose of this study was to assess, in an osteoarthritic (OA) model, whether bisphosphonate (BP) antiresorptive therapy altered periarticular bone and bone–ligament biomechanics OA progression. We surgically transected the anterior cruciate ligament (ACLX) two groups rabbits; first group dosed with BP (risedronate, 0.01 mg/kg s.c. daily for 6 wk), second remained untreated, a third normal (unoperated) control rabbits also evaluated. measured distal femoral mineral density (BMD,...
To understand more fully the early bone changes in an experimental model of osteoarthrosis, we quantified periarticular mineral density and mechanical properties anterior cruciate ligament transected (ACLX) knee joints (4, 10, 32, 39 wk post-ACLX) compared with contralateral unoperated normal skeletally mature animals. Maximal stress energy were significantly reduced ACLX cancellous from medial femoral condyles at 4 postinjury. All (e.g., yield elastic modulus) declined after 10 wk. was all...
Ultrafast lasers are promising tools for surgical applications requiring precise tissue cutting. Shallow ablation depth and slow rate as well collateral damage common barriers limiting the use of laser in clinical applications. Localized cooling with water and/or air jet is known to reduce thermal damage. We studied influence environmental conditions including air, compressed flow, still on depth, surface morphology bovine bone samples an 800 nm femtosecond laser. At 15 J/cm 2 , no effect...
When using ultrafast laser ablation in some orthopedic applications where precise cutting/drilling is required with minimal damage to collateral tissue, it challenging produce large-sized and deep holes a tightly focused beam. The feasibility of producing deep, millimeter-size structures under different strategies investigated. X-ray computed microtomography was employed analyze the morphology these structures. Our results demonstrated sizes clinical concentric helical protocols.
Abstract The hierarchy of newly formed bone contains elements disorder within an ordered multiscale structure, spanning from the macroscale to below nanoscale. With mineralized structures presenting in shape ellipsoids mature and mineralizing tissue, this work characterizes heterogeneity mineral ellipsoid packing at interface porous titanium implants. Using scanning transmission electron microscopy plasma‐focused ion beam–scanning microscopy, are characterized implant both 2D 3D....