Hao Liu

ORCID: 0000-0003-4649-116X
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About
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Research Areas
  • Analytical Chemistry and Chromatography
  • Chromatography in Natural Products
  • Magnetic and transport properties of perovskites and related materials
  • Metabolism and Genetic Disorders
  • Antibiotics Pharmacokinetics and Efficacy
  • Spectroscopy and Chemometric Analyses
  • Traditional Chinese Medicine Analysis
  • Rare-earth and actinide compounds
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Remote Sensing and Land Use
  • Analytical Methods in Pharmaceuticals
  • Plant-based Medicinal Research
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Essential Oils and Antimicrobial Activity
  • Heavy Metals in Plants
  • Remote Sensing in Agriculture
  • Magnetic Properties of Alloys
  • Mycotoxins in Agriculture and Food
  • Nitric Oxide and Endothelin Effects
  • Dye analysis and toxicity
  • Flavonoids in Medical Research
  • Genomics and Rare Diseases
  • Alkaloids: synthesis and pharmacology
  • Soil Geostatistics and Mapping
  • Thermal Expansion and Ionic Conductivity

China Pharmaceutical University
2006-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2025

University of Science and Technology Beijing
2023-2025

Hunan Academy of Traditional Chinese Medicine
2018-2025

Foshan University
2025

Materials Science & Engineering
2024

Huazhong Agricultural University
2021-2024

Henan University of Technology
2024

University of Electronic Science and Technology of China
2024

Chongqing Medical University
2015-2023

The sweet rhizomes of Polygonatum cyrtonema are widely used as a tonic and functional food. A sensitive rapid analytical method was developed for simultaneous identification dynamic analysis saccharides during steam processing in P. using HPLC⁻QTOF⁻MS/MS. Fructose, sorbitol, glucose, galactose, sucrose, 1-kestose were identified, well large number oligosaccharides constituted fructose units through β-(2→1) or β-(2→6). Polysaccharides decomposed to monosaccharides steaming process, since the...

10.3390/molecules23112855 article EN cc-by Molecules 2018-11-02

Inflammation, a central process in numerous diseases, plays crucial role hepatic disorders, arthritis, cardiac conditions, and neurodegenerative ailments. Given the lack of effective anti-inflammatory drugs, it is imperative to assess inflammation severity explore novel therapeutics. Selenocysteine (Sec), key mediator selenium's biological function, closely involved responses. We have synthesized near-infrared fluorescent probe, Sec-BDP, which can image Sec dynamics vivo with high...

10.1021/acs.analchem.4c02157 article EN Analytical Chemistry 2025-01-04

Bioactive compounds derived from herbal medicinal plants modulate various therapeutic targets and signaling pathways associated with cardiovascular diseases (CVDs), the world's primary cause of death. Ginkgo biloba, a well-known traditional Chinese medicine notable actions, has been used as cardio- cerebrovascular drug nutraceutical in Asian countries for centuries. Preclinical studies have shown that ginkgolide B, bioactive component can ameliorate atherosclerosis cultured vascular cells...

10.1016/j.apsb.2023.09.014 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2023-09-23

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common X-linked enzymopathies caused by G6PD gene variant. We aimed to provide characteristics and variant distribution in a large Chinese newborn screening population. investigated prevalence China from 2013 2017. Then, we examined activity representative birth cohort explore 2016. then performed multicolor melting curve analysis classify variants 10,357 neonates with activity-confirmed deficiency, DNA Sanger sequencing...

10.1002/humu.23911 article EN Human Mutation 2019-09-06

On the basis of similar fluorescence ethyl carbamate (EC) and urea derivatives, a high-performance liquid chromatography method coupled with detection was developed for simultaneous determination EC in alcoholic beverages. The chromatographic separation derivatization conditions were optimized. Under established conditions, limit, relative standard deviation, linear range, recovery 4.8 μg/L, 1.0-4.2%, 10-500 93.8-104.6%, respectively, EC; corresponding values 0.003 mg/L, 1.2-4.8%, 0.01-100...

10.1021/jf405400y article EN Journal of Agricultural and Food Chemistry 2014-03-11

Abstract A palladium‐catalyzed hydroalkylation of alkynes with cyclopropanols has been developed. This reaction provided a straightforward way to the synthesis γ,δ‐unsaturated ketones in moderate good yields, exhibiting high atom economy and Z/E selectivity. Deuterated tri‐substituted alkenes could also be expediently produced by using deuterium oxide as co‐solvent. magnified image

10.1002/adsc.201800200 article EN Advanced Synthesis & Catalysis 2018-06-14

The toxicity of heavy metals and harmful elements is highly dependent on their chemical species. However, research the simultaneous analysis inorganic organic species in complex matrices remains limited. This study presents a rapid sensitive method for concurrent determination arsenic selenium using reversed-phase chromatography with inductively coupled plasma-mass spectrometry. Enzyme-assisted extraction was employed to enhance efficiency target analyte recovery. By utilizing ion-pairing...

10.1002/jsfa.14211 article EN Journal of the Science of Food and Agriculture 2025-03-04

Headspace-gas chromatography-ion migration spectrometry (HS-GC-IMS) combined with chemometrics was used to analyze the changes in volatile aroma compounds (VOCs) at different production stages of steaming Polygonatum cyrtonema Hua. Fifty-seven representative process were identified, including 17 aldehydes, 15 alcohols, ketones, 5 esters, 3 furans, and 2 acids. After steaming, content 21 decreased. Among them, gradually decreased along an increase times; they 1-hexanol dimer, monomer,...

10.1155/jamc/5592877 article EN cc-by Journal of Analytical Methods in Chemistry 2025-01-01

Abstract Exploring and comprehending magnetocaloric materials with spin reorientation (SR) phase transition is of vital importance for practical applications effect (MCE). Herein, this study presents a systematic on the magnetic properties, heat transport structure, electronic structure NdNi compound. observed to undergo an SR ferromagnetic (FM) paramagnetic (PM) successively increasing temperature. Neutron powder diffraction (NPD) experiment reveals that involves rotation Nd moment from...

10.1002/aelm.202500119 article EN cc-by Advanced Electronic Materials 2025-03-21

The study of isothermal adsorption models for coal and methane under supercritical conditions helps us to understand the gas content distribution in seams improve management mines. Coal samples from Hebi mine Longshan were selected this research. Using weight method, curves at temperatures 308, 313, 318 K measured. phase density was obtained by using intercept method model fitting, absolute capacity calculated. Simultaneously, pore volume specific surface area tested, studied optimized....

10.1021/acsomega.4c06774 article EN cc-by-nc-nd ACS Omega 2024-09-27
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