A5084194434- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Nonlinear Dynamics and Pattern Formation
- Optical Imaging and Spectroscopy Techniques
- EEG and Brain-Computer Interfaces
- Technology and Human Factors in Education and Health
- Chaos control and synchronization
- Fusion and Plasma Physics Studies
- Complex Systems and Time Series Analysis
- ECG Monitoring and Analysis
- Infrared Thermography in Medicine
- Cardiac electrophysiology and arrhythmias
- Neural dynamics and brain function
- Hemodynamic Monitoring and Therapy
- Advanced Scientific Research Methods
- Cardiovascular Syncope and Autonomic Disorders
- Healthcare Systems and Public Health
- Advanced Chemical Sensor Technologies
- Human Health and Disease
- Heart rate and cardiovascular health
- Blood Pressure and Hypertension Studies
- Functional Brain Connectivity Studies
- Thermography and Photoacoustic Techniques
- Photoacoustic and Ultrasonic Imaging
- Neuroscience of respiration and sleep
Saratov State University
2015-2024
Institute of Radio-Engineering and Electronics
2015-2024
Institute of Physics
2021-2024
Saratov State Medical University
2019-2023
Immanuel Kant Baltic Federal University
2022-2023
Russian Academy of Sciences
2001-2023
Institute of Cardiology
2012-2023
Charité - Universitätsmedizin Berlin
2022
Institute of Higher Nervous Activity and Neurophysiology
2022
Innopolis University
2019-2021
We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1 Hz. A method is proposed for quantitative estimation these oscillating processes based on calculation relative time phase oscillations. It shown that healthy subjects exhibit average substantially longer epochs internal than patients after acute myocardial infarction.
To study the dynamical mechanism which generates Parkinsonian resting tremor, we apply coupling directionality analysis to local field potentials (LFP) and accelerometer signals recorded in an ensemble of 48 tremor epochs four patients with depth electrodes implanted ventro-intermediate nucleus thalamus (VIM) or subthalmic (STN). Apart from traditional linear Granger causality method use two nonlinear techniques: phase dynamics modelling causality. We detect a bidirectional between...
This paper describes in detail a new method proposed by authors for quantitative estimation of the strength synchronization between low-frequency oscillations (with main frequency about 0.1 Hz) heart rate variability (HRV) and photoplethysmogram (PPG). Calculation index value is followed statistical significance control. The applied analysis 1056 pairs HRV PPG signals obtained from patients having different clinical status. Methodological recommendations are developed application studies.
We propose a method that allows one to estimate the parameters of model scalar time-delay differential equations from time series. The is based on statistical analysis intervals between extrema in verify our by using it for reconstruction their chaotic solutions and modeling experimental systems with delay-induced dynamics
Synchronization between 0.1-Hz rhythms in cardiovascular system is deteriorated at acute myocardial infarction (AMI) leading to a disruption of natural functional couplings within the autonomic regulation.This study evaluates prognostic value regulation indices for 5-year risk fatal and nonfatal events patients after AMI.We studied 125 (53 [42%] female) AMI aged 30 83 years. The period observation was 5 years with checkpoints first week each year AMI. We compared established clinical...
We compare the spectral indices of photoplethysmogram variability (PPGV) estimated using photoplethysmograms recorded from earlobe and middle fingers right left hand analyze their correlation with similar heart rate (HRV) in 30 healthy subjects (26 men) aged 27 (25, 29) years (median inter-quartile ranges) at rest under head-up tilt test. The following PPGV HRV were compared: mean (HR), total power (TP), high-frequency (HF) low-frequency (LF) ranges TP percents (HF% LF%), LF/HF ratio,...
We study the synchronization of infra-slow oscillations in human scalp electroencephalogram signal with respiratory signal. For cases paced respiration a fixed frequency and linearly increasing frequency, we reveal phase locking brain potentials by respiration. It is shown that for different areas, can exhibit synchronous regimes orders.
The origin of complex irregular dynamics in a cardiovascular system is still being actively debated. Some hypotheses suggest the crucial role stochastic modulation parameters, while others argue for importance cardiac pacemakers' chaotic deterministic dynamics. In present study, we estimate largest Lyapunov exponent and correlation dimension 4-h experimental interbeat intervals signals generated by mathematical model system. We study complexity such cases as autonomic blockade, exclusion all...
Abstract A mathematical model is proposed for the autonomic control of cardiovascular system, which takes into account two separated self-exciting sympathetic loops heart rate and peripheral vascular tone. The are represented by time-delay systems their tone depends on activity aortic, carotid, lower-body baroreceptors. used to study dynamics adaptive processes that manifest in a healthy system during passive head-up tilt test. Computer simulation provides continuous observation indexes...
A new approach for detection oscillatory patterns and estimation of their dynamics based by a modified CWT skeleton method is presented. The opens up additional perspectives the analysis subtle changes in activity complex nonstationary signals. was applied to analyze unique experimental signals obtained usual conditions after non-invasive increase blood-brain barrier (BBB) permeability 10 male Wistar rats. results wavelet-analysis electrocorticography (ECoG) recorded normal physiological...
Cardiorespiratory interactions are important, both for understanding the fundamental processes of functioning human body and development methods diagnostics various pathologies. The properties cardiorespiratory interaction determined by autonomic control blood circulation, which modulated higher nervous activity. We study directional couplings between respiration process parasympathetic heart rate in awake state different stages sleep 96 healthy subjects from age groups. detection is carried...
We studied the properties of low-frequency (LF) heart rate variability (HRV) and photoplethysmographic waveform (PPGV) their interaction under conditions where hemodynamic connection between them is obviously absent, as well LF regulation PPGV in absence function. The parameters HRV finger were evaluated 10 patients during cardiac surgery cardiopulmonary bypass (on-pump surgery) with or without cardioplegia. following spectral indices ertimated: total power (TP), high-frequency (HF) ranges...
The lymphatic drainage system of the brain (LDSB) is removal metabolites and wastes from its tissues. A dysfunction LDSB an important sign aging, oncology, Alzheimer's Parkinson's diseases. development new strategies for diagnosis injuries can improve prevention age-related cerebral amyloid angiopathy, neurodegenerative cerebrovascular There are two conditions, such as deep sleep opening blood-brain-barrier (OBBB) associated with activation. promising candidate measurement could be...
Selection of the optimal dose beta-blocker treatment in myocardial infarction (MI) patients is problematic because a lack well-established guidelines.We evaluated changes synchronization between 0.1 Hz oscillations heart rate (HR) and plethysmographic peripheral microcirculation response to tilt-table test 3-month with highest tolerated (metoprolol) 43 aged 41 77 years acute MI 6 months prior start study. Before study were treated small doses beta-blocker. Phase differences HR used measure...