A5045539122- Neuroscience and Neuropharmacology Research
- Extracellular vesicles in disease
- Neuroscience and Neural Engineering
- Reproductive System and Pregnancy
- Sphingolipid Metabolism and Signaling
- Neural dynamics and brain function
- Cellular transport and secretion
- Big Data Technologies and Applications
- Sleep and Wakefulness Research
- Employer Branding and e-HRM
- Regulation of Appetite and Obesity
- Bacterial Infections and Vaccines
- Big Data and Digital Economy
- Advanced Memory and Neural Computing
- Erythrocyte Function and Pathophysiology
- Axon Guidance and Neuronal Signaling
- Retinal Development and Disorders
- Social Work Education and Practice
- Job Satisfaction and Organizational Behavior
- Innovation and Knowledge Management
- Public Administration, ICT, and Policy Development
- Apelin-related biomedical research
- Lipid Membrane Structure and Behavior
- Neuroinflammation and Neurodegeneration Mechanisms
- Big Data and Business Intelligence
Focus (Germany)
2022
University Medical Center of the Johannes Gutenberg University Mainz
2016-2022
Johannes Gutenberg University Mainz
2016-2022
Leibniz Institute for Resilience Research
2019-2022
Chinese Academy of Personnel Science
2010-2013
Stroke penumbra injury caused by excess glutamate is an important factor in determining stroke outcome; however, several therapeutic approaches aiming to rescue the have failed, likely due unspecific targeting and persistent excitotoxicity, which continued far beyond primary event. Synaptic lipid signaling can modulate glutamatergic transmission via presynaptic lysophosphatidic acid (LPA) 2 receptors modulated LPA-synthesizing molecule autotaxin (ATX) present astrocytic perisynaptic...
Communication with the hematopoietic system is a vital component of regulating brain function in health and disease. Traditionally, major routes considered for this neuroimmune communication are by individual molecules such as cytokines carried blood, neural transmission, or, more severe pathologies, entry peripheral immune cells into brain. In addition, functional mRNA from blood can be directly transferred to neurons via extracellular vesicles (EVs), but parameters that determine their...
Recording and manipulating neuronal ensemble activity is a key requirement in advanced neuromodulatory behavior studies. Devices capable of both recording brain-computer interfaces (BCIs) should ideally operate un-tethered allow chronic longitudinal manipulations the freely moving animal. In this study, we designed new intracortical BCI feasible telemetric stimulating local gray white matter visual neural circuit after irradiation exposure. To increase translational reliance, put forward...
Precise connection of thalamic barreloids with their corresponding cortical barrels is critical for processing vibrissal sensory information. Here, we show that PRG-2, a phospholipid-interacting molecule, important thalamocortical axon guidance. Developing fibers both in PRG-2 full knockout (KO) and thalamus-specific KO mice prematurely entered the plate, eventually innervating non-corresponding barrels. This misrouting relied on lost axonal sensitivity toward lysophosphatidic acid (LPA),...
Modulation of pathological neural circuit activity in the brain with a minimum complications is an area intense interest.The goal study was to alter neurons' physiological states without apparent damage cellular integrity using stereotactic radiosurgery (SRS).We treated 7.5 mm-diameter target on visual cortex Göttingen minipigs doses 40, 60, 80, and 100 Gy. Six months post-irradiation, pigs were implanted 9 mm-wide, eight-shank multi-electrode probe, which spanned radiation focus as well...
Two-photon (2-P) all-optical approaches combine in vivo 2-P calcium imaging and optogenetic modulations. Here, firstly, we combined juxtacellular recordings GCaMP6f-based mouse visual cortex to tune our detection algorithm towards a 100% specific identification of action potential-related transients. Secondly, minimized photostimulation artifacts by using extended-wavelength-spectrum laser sources for stimulation. We achieved artifact-free experiments performing stimulation from 1100 nm 1300...
The tsunami effect of the COVID-19 pandemic is affecting many aspects scientific activities. Multidisciplinary experimental studies with international collaborators are hindered by closing national borders, logistic issues due to lockdown, quarantine restrictions, and social distancing requirements. full impact this crisis on science not clear yet, but above-mentioned have most certainly restrained academic research Sharing innovative solutions between researchers in high demand situation....
Social work talents have been widely concerned by our society and academia while more social problems risen up under the background of constructing socialistic harmonious society. Hence, cultivating motivating become an extremely hot issue. Based on round analysis about current situation talents’ motivation, we synthetically use multiple human motivation strategies, bring forward approach innovative strategies’ combination which will fit needs talents. Key words: talent; Motivation strategy;...
Abstract Communication with the hematopoietic system is a vital component of regulating brain function in health and disease. Traditionally, major routes considered for this neuroimmune communication are either by individual molecules such as cytokines carried blood, neural transmission, or more severe pathologies, entry peripheral immune cells into brain. In addition, functional mRNA from blood can be directly transferred to neurons via extracellular vesicles (EVs) but parameters that...
Based on the review of in and out country public policy researches, We summarize difference between our research method overseas related domain, Totally 79 articles are reviewed. Then, we has constructed three dimensional model subject matter, including dimensions namely procedure, result appraisal interaction integrity. Finally, some suggestions for application proposed. Key words: Public Policy; Survey Method; Multi-fit Perspective
Personnel assessment and selection is one of the most effective approaches to obtain organizational competitive advantage. Traditional personnel technique based on competency can't satisfy need, therefore, emphasize importance P-J-O fit in context. Based ASD growth model, this study conduct a semi interview, find out that construct could include five aspects: competency, KSAs, Values, personality need-supplies.