A5055680475- Hemoglobinopathies and Related Disorders
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Sepsis Diagnosis and Treatment
- Platelet Disorders and Treatments
- Prenatal Screening and Diagnostics
- Blood Coagulation and Thrombosis Mechanisms
- Systemic Lupus Erythematosus Research
- Iron Metabolism and Disorders
- Blood properties and coagulation
- Hemophilia Treatment and Research
- Genomic variations and chromosomal abnormalities
- Neonatal Health and Biochemistry
- Emergency and Acute Care Studies
- Molecular Biology Techniques and Applications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Blood disorders and treatments
- COVID-19 and healthcare impacts
- HIV Research and Treatment
- Virus-based gene therapy research
- Long-Term Effects of COVID-19
- Healthcare Policy and Management
- Scoliosis diagnosis and treatment
Tongji Hospital
2016-2025
Huazhong University of Science and Technology
2016-2025
The First Affiliated Hospital, Sun Yat-sen University
2025
Zhongshan Hospital
2025
Sun Yat-sen University
2025
Guangzhou University of Chinese Medicine
2025
Shanghai Veterinary Research Institute
2024-2025
Tianjin Medical University
2025
Chinese Academy of Agricultural Sciences
2024-2025
Liaoning University of Traditional Chinese Medicine
2024-2025
<h3>Context</h3>The potential effects of increasing numbers uninsured and underinsured persons on US emergency departments (EDs) is a concern for the health care safety net.<h3>Objective</h3>To describe changes in ED visits that occurred from 1997 through 2007 adult pediatric populations by sociodemographic group, designation safety-net ED, trends ambulatory care–sensitive conditions.<h3>Design, Setting, Participants</h3>Publicly available visit data National Hospital Ambulatory Medical Care...
Severe coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy, the difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 has not been analyzed. Coagulation results clinical consecutive patients (COVID group) (non-COVID in Tongji hospital were retrospectively analyzed compared. Whether elevated D-dimer could benefit from anticoagulant treatment was evaluated. There 449 COVID 104 non-COVID enrolled into study. The 28-day...
The outbreak of novel coronavirus disease 2019 (COVID-19) has now become a global pandemic. Coagulopathy been reported widely in critically ill COVID-19 patients and was related to high mortality. However, the comprehensive coagulation profiles have not examined underlying mechanism coagulopathy is unclear. To study routine hemostasis tests, natural anticoagulants, coagulant factors antiphospholipid antibodies patients. This single-center cross-section included 19 with COVID-19, who were...
Summary Prolonged coagulation times, such as activated partial thromboplastin time (APTT) and thrombin (TT), are common in patients infected with severe fever thrombocytopenia syndrome virus (SFTSV) have been confirmed to be related patient's poor outcome by previous studies. To find out the reason for prolonged SFTSV infection, whether it predicts haemorrhagic risk or not. Seventy‐eight consecutive infection were enrolled this prospective, single‐centre, observational study. Several global...
The assays used to detect XMRV in patients with chronic fatigue syndrome are unreliable.
To compare single-molecule real-time technology (SMRT) and conventional genetic diagnostic of rare types thalassemia mutations, to analyze the molecular characteristics phenotypes gene variants, we used 434 cases with positive hematology screening as cohort, then SMRT diagnosis [(Gap-PCR, multiple ligation probe amplification (MLPA), PCR-reverse dot blot (RDB)] for screening. Among enrolled cases, identified 318 patients variants (73.27%) 116 without (26.73%), 361 (83.18%), 73 (16.82%). The...
Objectives This study aims to analyze the global burden of otitis media and predict future trends using data from Global Burden Disease 2021 (GBD 2021). Study design A cross-sectional analysis GBD results was conducted. Methods Age-standardized incidence rates (ASIR), age-standardized prevalence (ASPR), disability-adjusted life years (DALYs) (ASDR) were calculated. Trend conducted estimated annual percentage change (EAPC), Joinpoint regression, age-period-cohort, decomposition analyses....
Real-time PCR assays have recently been developed for diagnostic and research purposes. Signal generation in real-time is achieved with probe designs that usually depend on exonuclease activity of DNA polymerase (e.g. TaqMan probe) or oligonucleotide hybridization molecular beacon). Probe design often needs to be specifically tailored either tolerate differentiate between sequence variations. The conventional technologies offer limited flexibility meet these diverse requirements. Here, we...
XMRV, or xenotropic murine leukemia virus (MLV)-related virus, is a novel gammaretrovirus originally identified in studies that analyzed tissue from prostate cancer patients 2006 and blood with chronic fatigue syndrome (CFS) 2009. However, large number of subsequent failed to confirm link between XMRV infection CFS cancer. On the contrary, recent evidence indicates contaminant originating recombination two mouse endogenous retroviruses during passaging tumor xenograft (CWR22) mice,...
HIV RNA suppression is a key indicator for monitoring success of antiretroviral therapy. From logistical perspective, viral load (VL) testing using Dried Blood Spots (DBS) promising alternative to plasma based VL in resource-limited settings.To evaluate the analytical and clinical performance Abbott RealTime HIV-1 assay fully automated one-spot DBS sample protocol.Limit detection (LOD), linearity, lower limit quantitation (LLQ), upper (ULQ), precision were determined serial dilutions...
Tanshinone IIA (Tan-IIA) is the main bioactive component of Chinese herbal medicine salvia miltiorrhiza (Danshen). Sodium sulfonate Tan-IIA widely used in treatment cardiovascular and cerebrovascular diseases. also has inhibitory effects on tumor cells such as gastric cancer, but its therapeutic effect mechanism human neuroblastoma have not been evaluated, so pharmacological systematically evaluated by combined method network pharmacology molecular docking. PharmMapper SwissTargetPrediction...
Nucleic acid amplification test (NAAT)-based assays provide fast and sensitive results compared to conventional TB tests. The performance of the new Abbott Molecular MTB assay for qualitative detection complex using automated m2000™ system or manual sample preparation is summarized in this paper. detects eight subspecies. observed limit (LOD) when used an H37Rv panel was 2.45 colony forming units (cfu)/mL, while claimed LOD with strain 17 cfu/mL. No cross reactivity, carryover were study....
Clinical management of drug-resistant tuberculosis patients continues to present significant challenges global health. To tackle these challenges, the Abbott RealTime MTB RIF/INH Resistance assay was developed accelerate diagnosis rifampicin and/or isoniazid resistant within a day. This article summarizes performance assay; including reliability, analytical sensitivity, and clinical sensitivity/specificity as compared Cepheid GeneXpert MTB/RIF version 1.0 Hain MTBDRplus 2.0. The limit...