Mark Borchert

ORCID: 0000-0003-4704-9795
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About
Contact & Profiles
Research Areas
  • Ophthalmology and Visual Impairment Studies
  • Glaucoma and retinal disorders
  • Ophthalmology and Eye Disorders
  • Retinopathy of Prematurity Studies
  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • Cerebral Venous Sinus Thrombosis
  • Retinal Imaging and Analysis
  • Corneal surgery and disorders
  • Retinal and Optic Conditions
  • Fetal and Pediatric Neurological Disorders
  • Intraocular Surgery and Lenses
  • Ocular Disorders and Treatments
  • Neonatal and fetal brain pathology
  • Glioma Diagnosis and Treatment
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Optical Imaging and Spectroscopy Techniques
  • Ocular Diseases and Behçet’s Syndrome
  • Vestibular and auditory disorders
  • Visual perception and processing mechanisms
  • Pituitary Gland Disorders and Treatments
  • Neonatal Health and Biochemistry
  • Mitochondrial Function and Pathology
  • Multiple Sclerosis Research Studies
  • Pregnancy and preeclampsia studies

University of Southern California
2016-2025

Children's Hospital of Los Angeles
2016-2025

Southern California Eye Institute
2019-2024

APLA Health
2024

Minneapolis Institute of Arts
2023

Indianapolis Zoo
2023

Committee on Publication Ethics
2023

Keck Hospital of USC
2007-2021

Southern California University for Professional Studies
1992-2018

Harvard University
2015

To report an anatomic change following subretinal injection of voretigene neparvovec-rzyl (VN) for RPE65-mediated Leber congenital amaurosis. Multicenter, retrospective chart review. Patients who underwent VN at each 4 participating institutions. were identified as having perifoveal chorioretinal atrophy if (1) the areas not directly related to touch-down site cannula; and (2) area progressively enlarged over time. Demographic data, visual acuity, refractive error, fundus photographs, OCT,...

10.1016/j.oret.2021.03.016 article EN publisher-specific-oa Ophthalmology Retina 2021-04-08

To provide population-based normative data for monocular visual acuity (VA) and interocular differences in VA (IOD) Black Hispanic children 30 to 72 months of age without visually significant refractive errors or ophthalmic abnormalities.In a cohort the Multi-Ethnic Pediatric Eye Disease Study, HOTV measurements using Amblyopia Treatment Study protocol were analyzed continuous dichotomous outcomes IOD, after excluding subjects with abnormalities error.The analysis consisted 1722 aged months....

10.1097/opx.0b013e3181a76e55 article EN Optometry and Vision Science 2009-05-25

Opsoclonus-ataxia, also called "dancing eye syndrome," is a serious neurologic condition that often paraneoplastic manifestation of occult neuroblastoma in early childhood. Despite resection tumor and immunosuppressive therapy, outcome generally includes significant developmental behavioral sequelae. There controversy about how treatment alters outcome. The goals this study were to understand the ongoing deficits children who are treated for opsoclonus-ataxia with associated neuroblastoma;...

10.1542/peds.109.1.86 article EN PEDIATRICS 2002-01-01

Developmental delay has been reported to occur with optic nerve hypoplasia, a leading cause of pediatric blindness, but not systematically examined for its prevalence and correlation associated pathologies hypoplasia.The purpose this study was determine the developmental outcomes children hypoplasia development neuroradiographic, endocrinologic, ophthalmic findings.We conducted prospective analysis 73 subjects diagnosed at <36 months age 5 years age. Subjects underwent neuroradiographic...

10.1542/peds.2007-1825 article EN PEDIATRICS 2008-02-05

The vertebrate basic helix–loop–helix (bHLH) transcription factor ATOH7 (Math5) is specifically expressed in the embryonic neural retina and required for genesis of retinal ganglion cells (RGCs) optic nerves. In Atoh7 mutant mice, absence trophic factors secreted by RGCs prevents development intrinsic vasculature regression fetal blood vessels, causing persistent hyperplasia primary vitreous (PHPV). We therefore screened patients with hereditary PHPV, as well bilateral nerve aplasia (ONA) or...

10.1093/hmg/dds197 article EN Human Molecular Genetics 2012-05-29
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