- Heavy metals in environment
- Traumatic Brain Injury and Neurovascular Disturbances
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Erythropoietin and Anemia Treatment
- Monoclonal and Polyclonal Antibodies Research
- Mine drainage and remediation techniques
- Iron oxide chemistry and applications
- Nutrition and Health in Aging
- Intracranial Aneurysms: Treatment and Complications
- Geochemistry and Geologic Mapping
- Cardiac Arrest and Resuscitation
- Clinical Nutrition and Gastroenterology
- Geochemistry and Elemental Analysis
- Mast cells and histamine
- Glycosylation and Glycoproteins Research
- Food Allergy and Anaphylaxis Research
- Cytokine Signaling Pathways and Interactions
- Cardiac, Anesthesia and Surgical Outcomes
- Protein Kinase Regulation and GTPase Signaling
- Intensive Care Unit Cognitive Disorders
- Vascular Anomalies and Treatments
- Radioactive element chemistry and processing
- Arsenic contamination and mitigation
- Mercury impact and mitigation studies
Uppsala University Hospital
2013-2023
Uppsala University
2002-2023
Västmanlands sjukhus Västerås
2018
Umeå University
2005-2016
Saint Göran Hospital
2007-2010
Karolinska University Hospital
1981-2010
Lund University
2009
Multiple Sclerosis Society
2009
Swedish University of Agricultural Sciences
2003-2008
Stockholm University
2008
Associations with functional groups of natural organic matter (NOM) are great importance for bioavailability, toxicity, and mobility trace metals in soils waters. In this study, the coordination chemistry copper, Cu(II), dissolved (DOM) from streams was investigated by extended X-ray absorption fine structure (EXAFS) spectroscopy. both soil (SOM) DOM (990−11 000 μg Cu g-1 dry weight, pH 2.8−6.3), Cu(II) coordinated 4 oxygen/nitrogen (O/N) atoms at a distance 1.92−1.95 Å first shell. These...
The distribution of different iron (Fe) species in soils, sediments, and surface waters has a large influence on the mobility availability Fe, other nutrients, potentially toxic trace elements. However, knowledge about specific forms Fe that occurs these systems is limited, especially regarding associations with natural organic matter (NOM). In this study, extended X-ray absorption fine structure (EXAFS) spectroscopy was used to characterize Fe(III) soils (pH 4.6−6.0) varying content. EXAFS...
It is widely accepted that the bioavailability, toxicity, and mobility of trace metals are highly dependent on complexation reactions with functional groups in natural organic matter (NOM). In this study, coordination chemistry Cd NOM was investigated by extended X-ray absorption fine structure spectroscopy. Soil (SOM) from different types soils dissolved (DOM) an a mineral soil horizon Spodosol aquatic DOM Suwannee River were investigated. SOM samples (1000−25000 μg g-1, pH 4.6−6.6),...
The strong binding of CH3Hg+ to natural organic matter (NOM) in soils and waters determines the speciation CH3Hg under aerobic conditions indirectly its bioavailability rates demethylation. In lab experiments, halides (Cl, Br, I) were used as competing ligands determine strength solid-phase soil carbon (SOC) dissolved (DOC) a function time, pH, concentration halide. Experiments conducted with native concentra tions (1.7−9.8 ng g-1) soils, equilibrium concentrations determined by...
The complete nucleotide sequence of a mouse mastocytoma proteoglycan core protein mRNA was determined. mRNA, estimated to contain 1.1 kb, encodes with an Mr 16715. A 21-amino acid-residue region the is composed alternating serine and glycine residues. Southern-blot analysis genomic DNA cDNA containing sequences corresponding Ser-Gly repeat revealed more than 15 gene fragments. Hybridization probe N-terminal portion identified two fragments, covering C-terminal part 3′ untranslated hybridized...
Abstract Discrepancies between food content and label can lead to adverse reactions in people with hypersensitivity particular components. Over a 3‐year period, 20 occasions arose Sweden where discrepancies were confirmed. In 14 cases the investigation was initiated because of observed by individuals known disease. Analysis offending included qualitative quantitative antibody‐based techniques. The unexpected ingredients hazelnut, peanut, egg, milk, wheat, soy chicken protein. foods...
An assay, the paper radioimmunosorbent test (PRIST) for measurement of total serum IgE in rat, that allows down to a level 0.25 ng/ml, is described. With this assay it has been demonstrated significant differences exist normal levels non-immunized rats. These are strain-dependent, and strains may be classified as low (less than 50 ng/ml), medium (50--300 ng/ml) or high (greater 300 levels. The not sex-dependent. Environmental factors have pronounced influence, optimal housing conditions...
Thalidomide and bortezomib have been frequently used for second-line therapy in patients with myeloma relapsing after or refractory to initial melphalan-based treatment, but no randomized trials published comparing these two treatment alternatives.Thalidomide- bortezomib-naïve melphalan were randomly assigned low-dose thalidomide + dexamethasone (Thal-Dex) (Bort-Dex). At progression on either therapy, the offered crossover alternative drug combination. An estimated 300 would be needed trial...
Previous studies of spontaneous subarachnoid hemorrhage (SAH) have shown that global cerebral edema on the first computed tomography scan is associated with a more severe initial injury and an independent predictor poor outcome. Effects secondary ischemic events also influence outcome after SAH.This study demonstrates early related to markers increased energy metabolism as measured intracerebral microdialysis, which could increase vulnerability adverse events.Fifty-two patients microdialysis...