Torbjörn Karlsson

ORCID: 0000-0003-4707-8633
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About
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Research Areas
  • Heavy metals in environment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Iron Metabolism and Disorders
  • Hemoglobinopathies and Related Disorders
  • Erythropoietin and Anemia Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Mine drainage and remediation techniques
  • Iron oxide chemistry and applications
  • Nutrition and Health in Aging
  • Intracranial Aneurysms: Treatment and Complications
  • Geochemistry and Geologic Mapping
  • Cardiac Arrest and Resuscitation
  • Clinical Nutrition and Gastroenterology
  • Geochemistry and Elemental Analysis
  • Mast cells and histamine
  • Glycosylation and Glycoproteins Research
  • Food Allergy and Anaphylaxis Research
  • Cytokine Signaling Pathways and Interactions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Protein Kinase Regulation and GTPase Signaling
  • Intensive Care Unit Cognitive Disorders
  • Vascular Anomalies and Treatments
  • Radioactive element chemistry and processing
  • Arsenic contamination and mitigation
  • Mercury impact and mitigation studies

Uppsala University Hospital
2013-2023

Uppsala University
2002-2023

Västmanlands sjukhus Västerås
2018

Umeå University
2005-2016

Saint Göran Hospital
2007-2010

Karolinska University Hospital
1981-2010

Lund University
2009

Multiple Sclerosis Society
2009

Swedish University of Agricultural Sciences
2003-2008

Stockholm University
2008

Associations with functional groups of natural organic matter (NOM) are great importance for bioavailability, toxicity, and mobility trace metals in soils waters. In this study, the coordination chemistry copper, Cu(II), dissolved (DOM) from streams was investigated by extended X-ray absorption fine structure (EXAFS) spectroscopy. both soil (SOM) DOM (990−11 000 μg Cu g-1 dry weight, pH 2.8−6.3), Cu(II) coordinated 4 oxygen/nitrogen (O/N) atoms at a distance 1.92−1.95 Å first shell. These...

10.1021/es052211f article EN Environmental Science & Technology 2006-03-18

The distribution of different iron (Fe) species in soils, sediments, and surface waters has a large influence on the mobility availability Fe, other nutrients, potentially toxic trace elements. However, knowledge about specific forms Fe that occurs these systems is limited, especially regarding associations with natural organic matter (NOM). In this study, extended X-ray absorption fine structure (EXAFS) spectroscopy was used to characterize Fe(III) soils (pH 4.6−6.0) varying content. EXAFS...

10.1021/es800322j article EN Environmental Science & Technology 2008-06-27

It is widely accepted that the bioavailability, toxicity, and mobility of trace metals are highly dependent on complexation reactions with functional groups in natural organic matter (NOM). In this study, coordination chemistry Cd NOM was investigated by extended X-ray absorption fine structure spectroscopy. Soil (SOM) from different types soils dissolved (DOM) an a mineral soil horizon Spodosol aquatic DOM Suwannee River were investigated. SOM samples (1000−25000 μg g-1, pH 4.6−6.6),...

10.1021/es048585a article EN Environmental Science & Technology 2005-03-19

The strong binding of CH3Hg+ to natural organic matter (NOM) in soils and waters determines the speciation CH3Hg under aerobic conditions indirectly its bioavailability rates demethylation. In lab experiments, halides (Cl, Br, I) were used as competing ligands determine strength solid-phase soil carbon (SOC) dissolved (DOC) a function time, pH, concentration halide. Experiments conducted with native concentra tions (1.7−9.8 ng g-1) soils, equilibrium concentrations determined by...

10.1021/es034302n article EN Environmental Science & Technology 2003-10-09

The complete nucleotide sequence of a mouse mastocytoma proteoglycan core protein mRNA was determined. mRNA, estimated to contain 1.1 kb, encodes with an Mr 16715. A 21-amino acid-residue region the is composed alternating serine and glycine residues. Southern-blot analysis genomic DNA cDNA containing sequences corresponding Ser-Gly repeat revealed more than 15 gene fragments. Hybridization probe N-terminal portion identified two fragments, covering C-terminal part 3′ untranslated hybridized...

10.1042/bj2630105 article EN Biochemical Journal 1989-10-01

Abstract Discrepancies between food content and label can lead to adverse reactions in people with hypersensitivity particular components. Over a 3‐year period, 20 occasions arose Sweden where discrepancies were confirmed. In 14 cases the investigation was initiated because of observed by individuals known disease. Analysis offending included qualitative quantitative antibody‐based techniques. The unexpected ingredients hazelnut, peanut, egg, milk, wheat, soy chicken protein. foods...

10.1080/09540109409354827 article EN Food and Agricultural Immunology 1994-01-01

An assay, the paper radioimmunosorbent test (PRIST) for measurement of total serum IgE in rat, that allows down to a level 0.25 ng/ml, is described. With this assay it has been demonstrated significant differences exist normal levels non-immunized rats. These are strain-dependent, and strains may be classified as low (less than 50 ng/ml), medium (50--300 ng/ml) or high (greater 300 levels. The not sex-dependent. Environmental factors have pronounced influence, optimal housing conditions...

10.1111/j.1365-3083.1979.tb02725.x article EN Scandinavian Journal of Immunology 1979-03-01

Thalidomide and bortezomib have been frequently used for second-line therapy in patients with myeloma relapsing after or refractory to initial melphalan-based treatment, but no randomized trials published comparing these two treatment alternatives.Thalidomide- bortezomib-naïve melphalan were randomly assigned low-dose thalidomide + dexamethasone (Thal-Dex) (Bort-Dex). At progression on either therapy, the offered crossover alternative drug combination. An estimated 300 would be needed trial...

10.1111/j.1600-0609.2012.01775.x article EN European Journal Of Haematology 2012-03-08

Previous studies of spontaneous subarachnoid hemorrhage (SAH) have shown that global cerebral edema on the first computed tomography scan is associated with a more severe initial injury and an independent predictor poor outcome. Effects secondary ischemic events also influence outcome after SAH.This study demonstrates early related to markers increased energy metabolism as measured intracerebral microdialysis, which could increase vulnerability adverse events.Fifty-two patients microdialysis...

10.1227/01.neu.0000370893.04586.73 article EN Neurosurgery 2010-05-21
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