A5090998650- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Health and Disease Prevention
- Sodium Intake and Health
- Hormonal Regulation and Hypertension
- Cardiovascular Syncope and Autonomic Disorders
- Retinal Imaging and Analysis
- Metabolism, Diabetes, and Cancer
- Cardiovascular Disease and Adiposity
- Retinal Diseases and Treatments
- Adipose Tissue and Metabolism
- Hemodynamic Monitoring and Therapy
- Renal and Vascular Pathologies
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Cardiac electrophysiology and arrhythmias
- Diabetes Treatment and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Function and Risk Factors
- Pancreatic function and diabetes
- Cardiac Arrhythmias and Treatments
- Pharmacology and Obesity Treatment
- Streptococcal Infections and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Folate and B Vitamins Research
Royal Perth Hospital
2017-2024
The University of Western Australia
2017-2024
Hospital Research Foundation
2021-2024
WA Country Health Service
2023-2024
Medical Research Foundation
2019-2024
Curtin University
2014-2023
Tirunelveli Medical College
2014-2019
Pondicherry University
2014
Indian Institute of Science Bangalore
2013
Sree Balaji Dental College and Hospital
2012
Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide fewer than half of those with hypertension are aware it. May Measurement Month (MMM) a global campaign set up in 2017, raise awareness high BP as pragmatic solution lack formal screening worldwide. The 2018 was expanded, aiming include more participants countries.
Recent clinical trial data suggest a cardiorenal protective effect of sodium glucose cotransporter 2 (SGLT2) inhibition. We demonstrate that chemical denervation in neurogenic hypertensive Schlager (BPH/2J) mice reduced blood pressure, improved homeostasis, and renal SGLT2 protein expression. Inhibition prevented weight gain, significantly elevations tyrosine hydroxylase norepinephrine, protects against endothelial dysfunction. These findings provide evidence for significant crosstalk...
Recent sham-controlled randomized clinical trials have confirmed the safety and efficacy of catheter-based renal denervation (RDN). Long-term data beyond 3 years are scarce. Here, we report on outcomes after RDN in a cohort patients with resistant hypertension an average ≈9-year follow-up (FU).We recruited who were previously enrolled various applying radiofrequency energy for blood pressure (BP) lowering. All participants had baseline assessments before repeat assessment at long-term FU...
Protein glycation is a spontaneous reaction that believed to play key role in the pathogenesis of many clinical disorders. The proteins enhanced by elevated glucose concentrations. major form protein with consideration glycated haemoglobin (HbA1c). HbA1c fraction abnormally chronic hyperglycaemic diabetic patients and it correlates positively glycaemic control. However, increased levels have been documented iron de.ciency anaemic without any history diabetes.The aim this study was determine...
The haematological parameters are influenced by various factors like age, ethnicity, diet, genetic and gender differences hence it is important to define the specific reference values with regards region. indices Red Cell Distribution Width (RDW), Mean Platelet Volume (MPV) (PDW) newer which calculated automated haematology analyzers. There an increasing evidence that these clinically valuable bio markers. But not many studies have estimated intervals for in our population.Our primary...
Microvascular disease and rarefaction are key pathological hallmarks of hypertension. The retina uniquely allows direct, non-invasive investigation the microvasculature. Recently developed optical coherence tomography angiography now fine retinal capillaries, which may provide a superior marker overall vascular damage. This was prospective cross-sectional study to collect capillary density data on 300 normal eyes from 150 hypertensive adults, investigate possible associations with other...
The aim of this study was to develop an enteric coated insulin tablet formulation using polymers, absorption enhancer and enzyme inhibitor, which protect the tablets in acidic pH enhance systemic bioavailability.In study, influence coating by cellulose acetate hydrogen phthalate solution chosen excipients on Glut-4 transporter translocation C2C12 skeletal muscle cells examined. Following determination optimum number layers, two dissolution buffers such as 0.01 m hydrochloric acid, 2, 50 mm...