A5047053152- Economic and Financial Impacts of Cancer
- Central Venous Catheters and Hemodialysis
- Healthcare Systems and Practices
- Acute Lymphoblastic Leukemia research
- Advanced Breast Cancer Therapies
- Colorectal Cancer Treatments and Studies
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Breast Cancer Treatment Studies
- HER2/EGFR in Cancer Research
- Lymphoma Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Health Systems, Economic Evaluations, Quality of Life
- Childhood Cancer Survivors' Quality of Life
- Medical Imaging Techniques and Applications
- Health, Medicine and Society
- Global Cancer Incidence and Screening
- Cancer survivorship and care
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Cancer Treatment and Pharmacology
- Vascular Procedures and Complications
- Nutrition and Health in Aging
- Ocular Infections and Treatments
- Chemotherapy-related skin toxicity
Université de Rouen Normandie
2015-2025
Centre Virchow-Villermé
2020-2024
Centre Henri Becquerel
2020-2024
Université Paris Dauphine-PSL
2021-2022
Institut de Recherche pour le Développement
2022
Centre National de la Recherche Scientifique
2022
UniCancer Group
2021
Centre Hospitalier Universitaire de Rouen
2019
Inserm
2015-2019
Département d'Informatique
2018
•A reduction of the number cancer patients attending centers was observed in France from January to July 2020.•This only for newly diagnosed patients.•The new diagnosis more pronounced women, breast cancer, and prostate nonmetastatic cancer.•No compensation last months 2020. The magnitude delays may be larger within same country.•An estimation excess death resulting these is presented. BackgroundThe impact first coronavirus disease 2019 (COVID-19) wave on patient management measured...
This study evaluated the efficacy of pediatric-like acute lymphoblastic leukemia (ALL) therapy in adults with lymphoma (LL).This was a prospective phase II 18 to 59 years old previously untreated LL. Patients were treated an adapted ALL protocol, which included corticosteroid prephase, five-drug induction reinforced by sequential cyclophosphamide administration, dose-dense consolidation, late intensification, CNS prophylaxis, and 2-year maintenance phase. Treatment response assessed computed...
BackgroundYoung age is a poor prognostic factor in early stage breast cancer (BC) but its value less established metastatic BC (MBC). We evaluated the impact of at MBC diagnosis on overall survival (OS) across three groups (<40, 40 to 60 and > years(y)).MethodsESME database national cohort, collecting retrospective data from 18 participating French centers between January 01, 2008 December 31, 2014.ResultsAmong 14 403 women included, 1077 (7.5%), 6436 (44.7%) 6890 (47.8%) pts were <40, 40–60...
Rituximab has been demonstrated to be highly effective as a first‐line treatment for moderate‐to‐severe pemphigus; however, its high cost can considered limitation of this treatment. To compare direct costs two regimens, rituximab + short‐term prednisone vs. alone, tested in the Ritux3 trial. Patients were randomly assigned receive 2 g and 500‐mg maintenance infusions at month 12 18 along with low doses 3–6 months, or alone tapered over 12–18 months. We estimated related (i) protocol...
Both peripherally inserted central catheters (PICCs) and implanted port (PORTs) are commonly used for the delivery of immunochemotherapy. We compared safety two types devices in a homogeneous monocentric population diffuse large B-cell lymphoma (DLBCL) patients who were treated with first-line immunochemotherapy by evaluating numbers catheter-related venous thromboses (VTs) infections that occurred six months after implantation according to type device.Using propensity score, adjusted...
We conducted a prospective study to assess the prognostic impact of selected copy number variations (CNVs) in Stage II-III microsatellite stable (MSS) colon cancer. A total 401 patients were included from 01/2004 01/2009. The CNVs 8 target genes, DCC/18q, EGFR/7p, TP53/17p, BLK/8p, MYC/8q, APC/5q, ERBB2/17q and STK6/20q, detected using quantitative multiplex polymerase chain reaction short fluorescent fragment (QMPSF) method. primary end-point was on 4-year disease-free survival (DFS)....
Background/Aim: Vinorelbine is indicated for use in the treatment of MBC as a single agent or combination but there little real world data on this molecule and even less its oral form. We exploited Unicancer Epidemiology Strategy Medical-Economics (ESME) metastatic breast cancer (MBC) database to investigate current patterns vinorelbine (OV), well outcomes patients receiving drug. Patients Methods: Data were collected retrospectively from women men treated between 2008 2014 at one 18 French...
Abstract Background Although adjuvant cancer treatments increase cure rates, they may induce clonal selection and tumor resistance. Information still lacks as whether (neo)adjuvant anti-HER2 impact the patterns of recurrence outcomes HER2-positive (HER2+) metastatic breast (MBC). We aimed to assess this in large multicenter ESME real-world database. Patients Methods examined characteristics (overall survival (OS) progression-free under first-line treatment (PFS1)) HER2+ patients with MBC...
Late adjuvant chemotherapy (aCT) administration after colectomy (>56 d) is known to be associated with impaired prognosis. We aim identify risk factors late aCT, especially the travel time between patients' home and hospital.We performed a retrospective monocentre cohort study. Patients included had for stage III or high II colon cancer 2009 2015 at French university hospital. Risk aCT were identified using fractional polynomial logistic regression.Ninety-four patients included. The of was...
Abstract Factors associated with the choice of oral versus intravenous CT are not clearly established. Our purpose was to evaluate influence social status and home distance hospital on use in patients metastatic colorectal cancer (mCRC). This retrospective single‐center study included mCRC between 2011 2017. Patient assessed by European Deprivation Index (EDI) calculated. Univariable multivariable logistic regression analyses were performed. One hundred seventy‐five included, 71 receiving...