A5026346343- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Cutaneous Melanoma Detection and Management
- Urticaria and Related Conditions
- Cutaneous lymphoproliferative disorders research
- Allergic Rhinitis and Sensitization
- Health Systems, Economic Evaluations, Quality of Life
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Nonmelanoma Skin Cancer Studies
- Complementary and Alternative Medicine Studies
- Contact Dermatitis and Allergies
- Dermatological diseases and infestations
- Pharmaceutical studies and practices
- Nail Diseases and Treatments
- Melanoma and MAPK Pathways
- Acne and Rosacea Treatments and Effects
- Hidradenitis Suppurativa and Treatments
- Skin Protection and Aging
- Autoimmune and Inflammatory Disorders
- Skin Diseases and Diabetes
- Chemotherapy-related skin toxicity
- Systemic Sclerosis and Related Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Spondyloarthritis Studies and Treatments
Aix-Marseille Université
2016-2025
Assistance Publique Hôpitaux de Marseille
2016-2025
Hôpital de la Timone
2015-2025
Inserm
2014-2024
Groupe de Recherche sur le Psoriasis
2021-2024
Ceres
2020-2024
Centre National de la Recherche Scientifique
2024
Semmelweis University
2023
Sorbonne Université
2022
Collège de France
2018-2021
The assessment of the prevalence diseases is primary importance in planning health policies. No complete data on skin across European countries are available.To estimate most frequent conditions or 27 (24 EU countries, plus Norway, Switzerland, and United Kingdom).We conducted a population-based study representative extrapolable samples general population aged 18 years more each surveyed. Participants were selected using stratified, proportional sampling with replacement design. Data...
Abstract Alopecia areata is an autoimmune form of non‐scarring hair loss. It usually characterized by limited areas However, the disease may progress to complete scalp and body loss (alopecia totalis , alopecia universalis ). In patients with significantly impacts quality life. Children adolescents often experience bullying, including physical aggression. The severity evaluation tools used in clinical practice are: Severity Tool (SALT) score Areata Scale (AAS). A SALT equal or greater than...
Objective: To compare 5-year lesion recurrence rates in primary nodular basal cell carcinoma treated with topical methyl aminolevulinate photodynamic therapy (PDT) or simple excision surgery.
<h3>Background</h3> Early detection is crucial to improve melanoma prognosis. Different diagnostic guides such as the ABCD rule (asymmetry [A], irregularity of borders [B], unevenness distribution color [C], and diameter [D]) have been proposed identify melanoma, but their efficacy in real life questionable. We investigated recognition process by dermatologists use a model self-detection general population train students practitioners. <h3>Objectives</h3> To understand major principles nevi...
Currently no treat-to-target framework to guide systemic treatment in adults with moderate-to-severe atopic dermatitis exists. We sought reach international consensus through an eDelphi process on a core set of recommendations for such approach. Recommendations were developed by Steering Committee, spanning 3 areas (Guiding Principles, Decision Making, and Outcome Thresholds) 2 specific time-points; initial acceptable target at months optimal 6 months, each based improvements patient global...
Abstract Background Actinic keratoses ( AK ) are common photo‐induced cutaneous lesions that may progress to invasive squamous‐cell carcinoma and serve as a risk marker for skin cancer. Although numerous studies present the various therapeutic options , publications can be used pragmatically guide dermatologists in their daily practice limited. National international guidelines have been published, however, they based on clinical trials with highly selected patient populations do not always...
Understanding the contribution of ugly duckling sign (a nevus that is obviously different from others in a given individual) intrapatient comparative analysis (IPCA) nevi may help improve detection melanoma.To assess agreement dermatologists on identification and estimate IPCA to diagnosis melanoma.The same 2089 digital images sample 80 patients (mean age, 42 years [range, 19-80 years]; 33 men 47 women), as well 766 dermoscopic subset 30 40 21-75 12 18 were randomly presented 9 for blinded...
Abstract Systemic sclerosis (SSc) is a generalized disease of the connective tissue, arterioles, and microvessels, characterized by appearance fibrosis vascular obliteration. There are two main phenotypical forms SSc: diffuse cutaneous form that extends towards proximal region limbs and/or torso, limited where only affects extremities (without passing beyond elbows knees). also exists in less than 10% cases never involve skin. This called SSc sine scleroderma. The prognosis depends...
Background Hand decontamination is crucial to control nosocomial infections. The utility of hand related not only its antimicrobial effectiveness, but also acceptability by hospital staff. Objectives We aimed assess skin tolerance and effects two widely accepted hygiene measures under in-use conditions. Methods Fifty-two nurses were randomly assigned for an 8-day period either alcohol-based disinfectant or a wash with non-antiseptic soap. At baseline at the end test period, microbiological...
A prospective survey was conducted to assess the role of patients in melanoma prognosis. Consecutive with primary were interviewed and examined using a comprehensive questionnaire including psychological instrument. Main outcome measures delay before medical intervention tumor thickness. Of 590 melanomas, 70.8% detected by this proportion higher females. Relatives involved detection half cases. Median delays patient realized he had suspicious lesion, lesion seen doctor, removed 4 months, 2 1...
Background In uncontrolled before-after studies, CONSORT was shown to improve the reporting of randomised trials. Before-after studies ignore underlying secular trends and may overestimate impact interventions. Our aim assess 2007 STROBE statement publication on quality observational study reporting, using both analyses interrupted time series. Methods For this quasi-experimental study, original articles cohort, case-control, cross-sectional published between 2004 2010 in four dermatological...
Ipilimumab is a fully human monoclonal antibody directed against cytotoxic T-lymphocyte antigen-4 recently approved for the treatment of metastatic melanoma and currently under investigation in adjuvant setting high-risk stage III melanoma. The blockade CTLA-4 induces activation T cells, with an expected increase immunological reaction to cancer. We report case ipilimumab-induced Guillain-Barré syndrome revealed by occlusive enteric neuropathy. Two weeks after second dose ipilimumab, our...