A. Du‐Thanh
A5039942129- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Polyomavirus and related diseases
- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Nail Diseases and Treatments
- Mast cells and histamine
- Cutaneous Melanoma Detection and Management
- Melanoma and MAPK Pathways
- Full-Duplex Wireless Communications
- Viral-associated cancers and disorders
- Plant Virus Research Studies
- Systemic Lupus Erythematosus Research
- Fungal Infections and Studies
- Cancer and Skin Lesions
- Inflammatory Myopathies and Dermatomyositis
- Nonmelanoma Skin Cancer Studies
- Hemophilia Treatment and Research
- Lymphoma Diagnosis and Treatment
Université de Montpellier
2016-2025
Centre Hospitalier Universitaire de Montpellier
2016-2025
Inserm
2014-2025
Pathogenesis and Control of Chronic and Emerging Infections
2020-2024
Établissement Français du Sang
2024
Institut Pasteur
2015-2024
Société Française de Cardiologie
2024
Hôpital Saint Eloi
2014-2023
Université Paris Cité
2013-2022
Centre de Recherche Épidémiologie et Statistique
2022
Hereditary angioedema is a life-threatening illness caused by mutations in the gene encoding C1 inhibitor (also called esterase inhibitor) that lead to overactivation of kallikrein-bradykinin cascade. BCX7353 potent oral small-molecule plasma kallikrein with pharmacokinetic and pharmacodynamic profile may help prevent attacks.In this international, three-part, dose-ranging, placebo-controlled trial, we evaluated four doses (62.5 mg, 125 250 350 mg once daily) for prevention attacks over...
Development or Exacerbation of Head and Neck Dermatitis in Patients Treated for Atopic With DupilumabThe efficacy safety dupilumab, a humanized monoclonal antibody targeting the α subunit interleukin (IL)-4 IL-13 receptors, has been assessed adults with moderateto-severe atopic dermatitis (AD). 1,2 Injection site reactions, nasopharyngitis, conjunctivitis, transient increases eosinophil counts from baseline were higher dupilumab groups than placebo pivotal studies. 1,2A recent study by Zhu...
Abstract Objectives The specific roles of remission status, lupus low disease activity state (LLDAS), and damage accrual on the prognosis pregnancies in women with SLE are unknown. We analysed their impact maternal flares adverse pregnancy outcomes (APOs). Methods evaluated all (≥18 years) enrolled prospective GR2 study an ongoing singleton at 12 weeks (one pregnancy/woman). Several sets criteria were used to define remission, damage. APOs included: foetal/neonatal death, placental...
Hereditary angioedema (HAE) is a rare disease associated with either quantitative or qualitative deficiency in C1-inhibitor (C1-INH) normal C1-INH. HAE C1-INH 20% of cases mutations the gene for factor XII (FXII) FXII-HAE. A recent review described 41 families, including 14 German and 15 Spanish families. We have constructed register French patients their characteristics. national survey was launched through National Center Reference Angioedema (CREAK) to study clinical, biological...
GA2LEN, the Global Allergy and Asthma European Network, HAE international (HAEi), global umbrella organization for world's hereditary angioedema (HAE) patient groups, have launched their joint ACARE (Angioedema Center of Reference Excellence) program, within GA2LEN's center reference excellence (CORE) initiative. Angioedema is a common, heterogeneous, often debilitating chronic condition frequently challenge physicians affected patients, especially patients suffering from recurrent attacks....
The interest of long-term superpotent topical steroids (STS) in bullous pemphigoid (BP) has been supported by randomized controlled trials. However, inadequate compliance, poor cutaneous tolerance and nursing difficulties are potential drawbacks. Open-label studies on limited series patients suggested that low-dose methotrexate (MTX) may be useful, permitting maintenance a clinical remission obtained initial, short-term STS.Open, records-based retrospective analysis multicentre receiving...
Abstract Background Dupilumab is the first biotherapy available for treatment of moderate‐to‐severe childhood atopic dermatitis (AD). Objective The aim this study was to evaluate effectiveness and safety dupilumab in daily practice. Methods Patients aged 6–11, who had received a dose dupilumab, were included multicentre retrospective cohort study. primary endpoint change SCORAD after 3 months treatment. Secondary endpoints IGA score at months, proportion patients with SCORAD50 SCORAD75,...
Abstract Background Identification of myositis‐specific autoantibodies ( MSA s) for dermatomyositis DM ) could allow the characterization an antibody‐associated clinical phenotype. Objective We sought to define phenotype and risk cancer, interstitial lung disease ILD calcinosis based on . Methods A 3.5‐year multicentre prospective study adult patients was conducted determine associated with s presence calcinosis. Results were detected in 47.1% 117 included patients. Patients antimelanoma...