A5112646095- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Neuroimaging Techniques and Applications
- Cannabis and Cannabinoid Research
- Poisoning and overdose treatments
- Neural and Behavioral Psychology Studies
- Suicide and Self-Harm Studies
- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Alzheimer's disease research and treatments
- EEG and Brain-Computer Interfaces
Université de Montréal
2021-2025
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2021-2025
Hôpital du Sacré-Cœur de Montréal
2021-2024
Centre intégré universitaire de santé et de services sociaux du Nord-de-l’Île-de-Montréal
2021
Acute pain levels following orthopaedic injury (eg, fracture) are a predictor of the onset chronic pain, which affects nearly 50% fracture patients and impairs functional recovery. Among current pharmacological treatments for acute non-steroidal anti-inflammatory drugs have been associated with delayed bone healing, while opioids inhibit effective remodelling, increase risk pseudarthrosis carry high addiction. In light this, development new is essential. Cannabidiol (CBD), non-addictive...
Abstract Alzheimer's disease is associated with pre-symptomatic changes in brain morphometry and accumulation of abnormal tau amyloid-beta pathology. Studying the development prior to symptoms onset may lead early diagnostic biomarkers a better understanding pathophysiology. pathology thought arise from combination protein spreading via neural connections, but how these processes influence atrophy progression phases remains unclear. Individuals family history (FHAD) have an elevated risk...
Background/Objectives: The insula plays a role in various medical conditions, including eating disorders, addiction, and chronic pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as promising therapeutic avenue, yet few studies have investigated its modulation effects on the insula. Moreover, direct evidence of target engagement remains scarce. This study aimed to stimulate with rTMS assess BOLD signal through concurrent functional resonance imaging (fMRI). Methods: Ten...
Transcranial alternating current stimulation, a non-invasive brain stimulation technique, has been used to increase alpha (8-12 Hz) power, the latter being associated with various functions and states. Heterogeneity among parameters across studies makes it difficult implement reliable transcranial protocols, explaining absence of consensus on optimal modulate rhythm. This project documents differential impact controlling for key parameters, namely intensity, frequency site (anterior versus...
Introduction Therapeutic interventions for disorders of consciousness lack consistency; evidence supports non-invasive brain stimulation, but few studies assess neuromodulation in acute-to-subacute brain-injured patients. This study aims to validate the feasibility and effect a multi-session transcranial alternating current stimulation (tACS) intervention subacute patients on recovery consciousness, related oscillations network dynamics. Methods analyses The is comprised two phases:...
Altered extracellular amino acid concentrations following concussion or mild traumatic brain injury can result in delayed neuronal damage through overactivation of NMDA glutamatergic receptors. However, the consequences repeated concussions prior to complete recovery are not well understood. In this study, we utilized vivo cerebral microdialysis and a weight-drop model investigate acute neurochemical response single adult rats that were fully conscious. A probe was inserted into hippocampus...