A5049201115- Rabies epidemiology and control
- Tuberculosis Research and Epidemiology
- Bacteriophages and microbial interactions
- Bacillus and Francisella bacterial research
- Mycobacterium research and diagnosis
- Toxoplasma gondii Research Studies
- Virology and Viral Diseases
- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Diagnosis and treatment of tuberculosis
- Poxvirus research and outbreaks
- Virus-based gene therapy research
- T-cell and Retrovirus Studies
- HIV Research and Treatment
- Human Health and Disease
- Vector-Borne Animal Diseases
- Fire effects on ecosystems
- Brucella: diagnosis, epidemiology, treatment
- Escherichia coli research studies
- Medicinal Plants and Bioactive Compounds
- Microbial infections and disease research
Kazan State Medical Academy
2014-2023
Russian Medical Academy of Continuous Professional Education
2017-2023
Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
2023
Kazan Scientific Center
2017-2021
Federal Research Centre of Nutrition and Biotechnology
2015
Leptospirosis is a widespread natural focal zoonotic disease that threatens epidemic and epizootic well-being. Bacteriological, serological molecular genetic methods exist for laboratory diagnostics of leptospirosis. In samples the studied material obtained from animals environment, pathogenic leptospires are in most cases present small quantities, based on this, nested polymerase chain reaction (PCR) method one optimal detecting these pathogens due to its higher sensitivity specificity....
SUMMARY This report summarizes epidemiological data on nephropathia epidemica (NE) in the Republic of Tatarstan, Russia. NE cases identified period 1997–2013 were investigated parallel with hantavirus antigen prevalence small rodents study area. A total 13 930 documented all but one district most located central and southeastern districts. The annual incidence rate exhibited a cyclical pattern, highest numbers being registered once every 3–5 years. rose gradually from July to November,...
Background and Aim: Several reports described the detection of specific caprine arthritis-encephalitis virus (CAEV) antibodies in Russian goat populations, which indicates circulation CAEV farms. The aim this study was to use a multi-target approach testing with both serological tests an in-house real-time (RT) molecular test investigate prevalence goats from three hobbyist farms Republic Tatarstan, Russia. Materials Methods: We applied enzyme-linked immunosorbent assay (ELISA) RT polymerase...
Abstract Toxoplasma gondii is a zoonotic parasite with wide host range that includes humans, domestic animals and wild animals. Small mammals serve as intermediate hosts for T. may contribute to the persistence of this in environment. Mass mortality deaths rare endemic species make study growing importance. In study, infection prevalence was evaluated brain tissues from 474 small captured at 26 trapping points urban rural areas Tatarstan, Russian Federation. Nested PCR used detect B1 gene...
Proteins are considered to be the main carriers of antigenic properties Mycobacterium tuberculosis and bovis, causative agents tuberculosis, most serious infectious disease. Neutrophils, following resident macrophages, among first attack mycobacteria in defense organism. Neutrophils themselves also target mycobacterial products; their effect on neutrophil functions has been less studied. We have obtained about 70 protein fractions from M. bovis lysate; them four (10, 22, 24, 40 kDa) had high...
Diagnosis of leukemia remains one the key problems in carrying out recreational activities farms that are disadvantaged by this disease. In Russian Federation, various methods used to identify causative agent leukemia, including serological methods, which is enzyme immunoassay (ELISA). The principle indirect variant ELISA a complex formed an antigen immobilized on surface wells polystyrene tablet and specific antibodies contained blood serum samples or cattle milk. present work devoted study...
Objective of the study is to evaluate serological activity rabies virus antigens isolated from brain tissue mice by homogenization on FastPrep followed ultracentrifugation. Materials and methods. Producer strain “Ovechiy” GNKI. The was experimentally infected mice, electrophoretic profile. components assessed immunoblot ELISA using specific anti-rabies sera. Results conclusions. In course comparing methods isolation purification antigen, it found that most optimal one use a FastPrep-24,...
The aim of the work was to develop an approach isolation rabies virus glycoprotein applying threephase extraction and characterize its antigenic properties. Materials methods . Infectious activity (production strain, “Ovine” GNKI) after long-term storage restored on white BALB/c mice. strain used for cultivation BHK-21 cells; culture liquid concentrated ultracentrifugation followed by separation buoyant density in a sucrose gradient, selection visually opalescent zones, phase concentration,...
In this study we have approached the detection of caprine arthritis-encephalitis virus (CAEV) using a multi target approach testing with both ELISA and an in-house real-time PCR test to investigate prevalence CAEV in goats from hobbyist farms Republic Tatarstan, Russia. Animals three were used study. The animals two (n=13 for F1 n=8 F2) had clinical signs arthritis mastitis. third farm (n=15 F3), all homebred no contact imported animals. antibodies (ELISA targets TM ENV GaG genes) detected...
Aim: The aim of this study was to use a multi target approach testing with both serological tests and an in-house real-time molecular test investigate the prevalence caprine arthritis-encephalitis virus (CAEV) in goats from three hobbyist farms Republic Tatarstan, Russia. Materials Methods: We have approached detection using ELISA PCR CAEV goats. Animals were used study. animals two (n=13 for F1 n=8 F2) had clinical signs arthritis mastitis. In third farm (n=15 F3), all homebred no contact...
The results of the comparative study diagnostic efficacy method isolation street rabies virus using rat Gasser‘s ganglion neurinoma cell culture (RGGN-1) and biological tests on white mice are presented. It is shown that RGGN-1 not inferior in sensitivity to classic bioassay has obvious advantages, such as reducing time diagnosis (up 3 days compared 30 mice) its cost-effectiveness. Method line RGGN-1infection recommended for inclusion Standards rapid virus, which should be considered a...
Tuberculosis is a dangerous socially significant disease of various animal species. According to Rosselkhoznadzor data for 2022, the situation with bovine tuberculosis endemic, stable, long-term trends are decreasing, epidemic thresholds ill health and incidence have not been overcome. It should be noted that in was officially detected, but this infection registered several pigs wild boars. Take point reduction number cases cattle decreased (to zero), overall strategy combating successful,...
Цель работы. Оценка серологической активности антигенов вируса бешенства, выделенных из мозговой ткани мышей гомогенизацией на FastPrep с последующим ультрацентрифугированием. Материалы и методы. В работе использовали производственный штамм бешенства «Овечий» ГНКИ. Вирусный материал выделяли экспериментально зараженных мышей. Электрофоретический профиль изучали по белковой, полисахаридной гликолипидной составляющим. Серологическую активность компонентов определяли иммуноблотом ИФА...