A5016973546- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Kawasaki Disease and Coronary Complications
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Family and Patient Care in Intensive Care Units
- Airway Management and Intubation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- COVID-19 Impact on Reproduction
- Tracheal and airway disorders
- Trauma and Emergency Care Studies
- Nosocomial Infections in ICU
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
- Mechanical Circulatory Support Devices
- COVID-19 and Mental Health
- Child and Adolescent Health
- Social Media in Health Education
- Health Systems, Economic Evaluations, Quality of Life
- Global Maternal and Child Health
Centro Hospitalario Pereira Rossell
2017-2025
Universidad de la República de Uruguay
2021-2025
RedCLARA
2019-2025
Universidad La República
2023-2024
SingHealth
2023
King Saud bin Abdulaziz University for Health Sciences
2023
KK Women's and Children's Hospital
2023
Sociedad Española de Cuidados Intensivos Pediátricos
2020-2021
Agostino Gemelli University Polyclinic
2021
Università Cattolica del Sacro Cuore
2020
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, disproportionally affects adults (children <5% in most reports).1 Adult critical illness is characterized hypoxemia, multiorgan failure, and high mortality.2,3 Reported risk factors for include age, cardiorespiratory comorbidities, obesity, laboratory findings (lymphopenia elevated D-dimer).2,4 Pediatric reports describe low infection rates infrequent PICU admission.5,6 The largest report consists...
Background The COVID-19 pandemic reached the Southern Hemisphere in autumn of 2020, thus coinciding with its expected annual viral respiratory season. potential impact national strategies aimed at mitigating during on incidence other critical lower tract infections (LRTIs) children is unknown. Methods We analysed admission data for LRTIs from 22 paediatric intensive care units (PICUs) four countries, part a large international Latin American registry acute failure (Red Colaborativa...
To understand critical paediatric coronavirus disease 2019 (COVID-19) and evaluate factors associated with mortality in children from high low-middle income countries.Prospective, observational study of critically ill hospitalised for COVID-19 18 countries throughout North America, Latin Europe between April 1 December 31, 2020. Associations were evaluated using logistic regression.557 patients (median age, 8 years; 24% <2 years) enrolled 55 sites (63% American). Half had comorbidities....
The true global burden of paediatric critical illness remains unknown. Studies on children with life-threatening conditions are hindered by the absence a common definition for acute (DEFCRIT) that outlines components and attributes does not depend local capacity to provide care. We present an evidence-informed consensus framework illness. DEFCRIT was developed following scoping review 29 studies key concepts identified interdisciplinary, international core expert panel (n=24). A modified...
Importance The use of hypertonic saline (HTS) vs mannitol in the control elevated intracranial pressure (ICP) secondary to neurotrauma is debated. Objective To compare mortality and functional outcomes treatment with 3% HTS 20% among children moderate severe traumatic brain injury (TBI) at risk ICP. Design, Setting, Participants This prospective, multicenter cohort study was conducted between June 1, 2018, December 31, 2022, 28 participating pediatric intensive care units Pediatric Acute...
OBJECTIVES: To describe the infrastructure and resources for pediatric emergency critical care delivery in resource-limited settings worldwide. DESIGN: Cross-sectional survey with items developed through literature review revised following piloting. SETTING: The electronic was disseminated internationally November 2019 via e-mail directories of intensive societies networks using social media. PATIENTS: Healthcare providers who self-identified as working settings. INTERVENTIONS: None....
Objectives: To determine the prevalence of respiratory bacterial codetection in children younger than 2 years intubated for acute lower tract infection (LRTI), primarily viral bronchiolitis, and identify association with mechanical ventilation duration. Design: Prospective observational study evaluating (moderate/heavy growth pathogenic plus moderate/many polymorphonuclear neutrophils) impact on invasive (IMV) Setting: PICUs 12 high low/middle-income countries. Patients: Children old...
OBJECTIVE The burden of traumatic brain injury (TBI) is disproportionately high in low- and middle-income countries (LMICs). This study aimed to compare clinical outcomes healthcare utilization for children with moderate severe TBIs between LMICs non-LMICs Asia Latin America. METHODS authors performed an observational multicenter from January 2014 February 2023 among admitted participating pediatric intensive care units (PICUs) the Pediatric Acute Critical Care Medicine Asian Network...
Bronchiolitis and other lower respiratory tract infections (LRTIs) are the most common causes of pediatric failure. There is insufficient evidence characterizing acute distress syndrome (PARDS) in young children with LRTI to inform clinical management. We aimed describe prevalence characteristics intubated for meeting PARDS criteria. performed a post hoc analysis data from And COdetectioN (BACON) study, an international prospective observational study critical bronchiolitis. compared...
Analysis of respiratory mechanics during mechanical ventilation (MV) is able to estimate resistive, elastic and inertial components the working pressure system. Our aim was discriminate system in infants on MV with severe bronchiolitis admitted two PICU's. Infants younger than 1 year old acute failure caused by underwent neuromuscular blockade, tracheal intubation volume controlled MV. Shortly after studies pulmonary were performed using inspiratory expiratory breath hold. The maximum flow...
There are many reasons why the international community as a whole should advocate for COVID-19 vaccine equity: global economic recession, uncontrolled outbreaks with higher risk of virus variants and persistent unsafe travelling in an era now vaccine-preventable cause death. This inequity is avoidable threat to health. Funding agencies, policy makers, drug companies NGOs among others have moral duty end this apartheid make equity reality. In viewpoint, we discuss how inequalities vaccination...
Objective: The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment sepsis in children low- middle-income countries (LMICs), more specifically Latin America. Design: A panel formed consisting 27 experts with experience pediatric two methodologists working American countries. were organized into 10 nominal groups, each coordinated by a member. Methods: formal consensus based on modified Delphi method, combining opinions groups interpretation...
To compare the new tools to evaluate energy dissipated lung parenchyma in mechanically ventilated children with and without injury. We compared their discrimination capability between both groups when indexed by ideal body weight driving pressure.Post hoc analysis of individual patient data from two previously published studies describing pulmonary mechanics.Two academic hospitals Latin-America.Mechanically patients younger than 15 years old were included. analyzed groups, 30 under general...
Background Children with cancer are at risk of critical disease and mortality from COVID-19 infection. In this study, we describe the clinical characteristics pediatric patients multiple Latin American centers factors associated in population. Methods This study is a multicenter, prospective cohort conducted 12 hospitals 6 countries (Argentina, Bolivia, Colombia, Ecuador, Honduras Peru) April to November 2021. Patients younger than 14 years age that had an oncological diagnosis or...
Periextubation corticosteroids are commonly used in children to prevent upper airway obstruction (UAO). However, the best timing and dose combination of is unknown.