A5053680444- Mesenchymal stem cell research
- Facial Rejuvenation and Surgery Techniques
- Railway Engineering and Dynamics
- Dermatologic Treatments and Research
- Body Contouring and Surgery
- Geotechnical Engineering and Underground Structures
- Periodontal Regeneration and Treatments
- Tissue Engineering and Regenerative Medicine
- Neonatal Respiratory Health Research
- Mechanical stress and fatigue analysis
- Electrospun Nanofibers in Biomedical Applications
- Hair Growth and Disorders
- Bone Tissue Engineering Materials
- Dental Anxiety and Anesthesia Techniques
- Retinoids in leukemia and cellular processes
- Advanced Proteomics Techniques and Applications
- Body Image and Dysmorphia Studies
- Simulation and Modeling Applications
- Reconstructive Surgery and Microvascular Techniques
- Fibroblast Growth Factor Research
- Facial Nerve Paralysis Treatment and Research
- Bone and Dental Protein Studies
- Civil and Geotechnical Engineering Research
- Pediatric health and respiratory diseases
- Corneal Surgery and Treatments
Shanghai Tenth People's Hospital
2014-2025
Tongji University
2014-2025
Guangzhou Municipal Engineering Design and Research Institute
2024
Sun Yat-sen University
2024
China Federation of Supply and Marketing Cooperatives
2021-2022
Fruit Research Institute
2021-2022
Beijing Jiaotong University
2020-2021
Shandong Normal University
2017
Qingdao University of Science and Technology
2016
Beihang University
2016
Exploring bone proteome is an important and challenging task for understanding the mechanisms of physiological/pathological process tissue. However, classical methods protein extraction soft tissues cells are not applicable Therefore, method development efficient critical analysis. We found in this study that efficiency was improved significantly when tissue demineralized by hydrochloric acid (HCl). A sequential developed large-scale analysis The first HCl solution then extracted using three...
Bone graft substitutes with osteogenic factors alone often exhibit poor bone regeneration due to inadequate vascularization. Combined delivery of and angiogenic from biodegradable scaffolds may enhance regeneration. We evaluated the effects morphogenetic protein 2 (BMP2) vascular endothelial growth factor (VEGF), combined natural coral scaffolds, on repair critical-sized defects in rabbit orbits. In vitro expanded marrow stromal cells (BMSCs) were transfected human BMP2 VEGF165 genes. Target...
Tissue engineering has become a new approach for repairing bone defects. Previous studies indicated that coral scaffolds had been utilized with marrow stromal cells (BMSCs) in variety of approaches bony reconstruction. In these applications, the degradation rate material did not match at which was regenerated. this study, previously established 30 mm long mandibular segmental defect repaired engineered using green fluorescent protein-labeled osteogenic BMSCs seeded on porous (n = 12)....
Parkinson's disease (PD) is a devastating of the central nervous system that occurs mainly in elderly age group, affecting their quality life. The PD pathogenesis not yet fully understood and lacks disease-modifying treatment strategies. Sanghuangprous vaninii (S. vaninii) perennial fungus with plethora pharmacological activities including anti-cancer antioxidant activity so on. However, no study till date has reported its neuroprotective effect against symptoms are similar to pre-clinical...
The reconstruction of large craniofacial defects remains a significant clinical challenge. complex geometry facial bone and the lack suitable donor tissue often hinders successful repair. One strategy to address both these difficulties is development an in vivo bioreactor, where flap can be orthotopically grown within same patient requiring reconstruction. Our group has previously designed such approach using chambers filled with morcellized autograft as scaffold autologously generate...
The reconstruction of large-sized soft tissue defects remains a substantial clinical challenge, with adipose engineering emerging as promising solution. acellular dermal matrix (ADM), known for its intricate spatial arrangement and active cytokine involvement, is widely employed scaffold in engineering. Since ADM shares high similarity decellularized matrix, it holds potential substitute tissue. This study explores the adipogenic ability spongy material derived from via vacuum-thermal...
Purpose: This study aimed to evaluate the effects of a new treatment—conditioned medium from human orbital adipose-derived stem cells (OASC-CM)—on corneal recovery after alkali burns in rabbit model. Methods: The burn model was established and treated with OASC-CM, conditioned abdominal subcutaneous (ABASC-CM), fresh control culture (con-CM) three times day for 7 days, respectively. Subsequently, treatment were evaluated compared through clinical, histological, immunohistochemical, cytokine...
Background: Allergic rhinitis (AR) is a common immune disease of the nasal mucosa characterized with immunoglobulin E (IgE)-mediated allergic inflammation after exposure to allergens in susceptible population. Previous reports have demonstrated that bone marrow mesenchymal stem cells (BMSCs) could reduce inflammation. However, there little knowledge about whether culture supernatant BMSCs (conditioned medium, CM) has similar anti- inflammatory potential treating AR. Objective: The study...
Autologous fat grafting has become an increasingly common procedure for soft tissue augmentation throughout the body. However, long-term outcome is always unpredictable because of inconsistent graft survival. Based on "law use and disuse," we speculate that volume loss grafts will occur when transferred into a site where there less fat. The purpose this study to investigate cause high resorption rate from perspective function after transplantation.Adipose aspirates obtained routine...
Abstract Background Both perilipin1 (Plin1) and perilipin2 (Plin2) play a crucial role in regulating lipid droplet (LD) formation fat cells. Plin2 is expressed early the adipocyte differentiation process but replaced by Plin1 after cell maturation. In free grafts, only small number of adipocytes remain alive or are newly regenerated It known that Plin1-positive participate regeneration, characteristics expression during this still poorly understood. Objectives The aim study was to...
The Asian eyelid has distinctive anatomical properties. Although the upper is reported in literature to have no subcutaneous fat layer, we often noticed adipose tissue below skin during ophthalmic plastic surgeries. aim of present study was examine and histological features eyelids using biopsies microscopic morphological analysis. A total 30 Chinese patients (60 eyelids) undergoing blepharoplasty were evaluated. surgically harvested examined histologically. This yielded two main findings....
The color difference in human subcutaneous fat (SF) and orbital (OF) is apparent, but the reasons have been rarely elaborated. We speculate that differences carotenoid lipid contents may account for discrepancy color. In this study, intrinsic SF OF were analyzed using ultrahigh-performance liquid chromatography coupled with Q-Exactive mass spectrometry/mass spectrometry (UPLC-QE Plus LC-MS/MS). Lipid profiling was performed an independent batch. morphology between septum differed...
For the winemaking bioprocess of jujube wine, selection optimal starter cultures is one major concerns before fermentation. In this study, we investigated effects different yeasts on composition aroma-active compounds in fermented wine and identified principal components that determine flavor quality. It showed produced a total 43 compounds, which esters (e.g., ethyl caprylate, decanoate, hexanoate, phenethyl acetate) contribute more to quality attributes, especially for improvement aroma....
Objective To investigate the feasibility of using human umbilical cord blood derived mesenchymal stem cells (UCB-MSCs) and demineralized bone matrix (DBM) scaffolds to repair critical-sized calvarial defects in athymic rats. Methods Human UCB-MSCs were isolated, expanded osteogenically induced vitro. Osteogenic differentiation was evaluated by Alizarin Red staining measurement calcium content respectively, then seeded onto DBM scaffolds. Bilateral full-thickness (5 mm diameter) parietal...