A5053533983- Ovarian function and disorders
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Reproductive Health and Technologies
- Pregnancy and preeclampsia studies
- Uterine Myomas and Treatments
- Birth, Development, and Health
- Reproductive System and Pregnancy
- Hormonal and reproductive studies
- Sperm and Testicular Function
- Menopause: Health Impacts and Treatments
- Ovarian cancer diagnosis and treatment
- Pelvic floor disorders treatments
- Gestational Diabetes Research and Management
- Neonatal Respiratory Health Research
- Healthcare Policy and Management
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Estrogen and related hormone effects
- Neonatal and fetal brain pathology
- Reproductive Health and Contraception
- Urinary Tract Infections Management
- Global Maternal and Child Health
University of Florida Health
2010-2024
University of Rochester
2002-2024
Brown University
2024
University of Florida
1986-2021
Institut de Médecine de la Reproduction
2021
Association of American Medical Colleges
2017
Health Affairs
2010-2016
University of Florida Health Science Center
2011-2016
Beijing Obstetrics and Gynecology Hospital
2006-2009
University of Rochester Medical Center
1995-2008
Although semen analysis is routinely used to evaluate the male partner in infertile couples, sperm measurements that discriminate between fertile and men are not well defined.
Abstract —Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance. An adverse lipid profile has also been observed in PCOS-affected women, suggesting that these individuals may be at increased risk for coronary heart disease young age. The objective of the present study was to evaluate subclinical atherosclerosis among women with PCOS age-matched control subjects. A total 125 white cases 142 controls,...
Induction of superovulation with gonadotropins and intrauterine insemination are frequently used to treat infertility. We conducted a large, randomized, controlled clinical trial these treatments.
The goal of the study was to compare cardiovascular heart disease risk factors in women with polycystic ovary syndrome (PCOS) and matched control subjects. Women PCOS have factors, including anovulation, hyperandrogenism, insulin resistance, that suggest a male coronary risk-factor profile. A total 206 were recruited by using records from large reproductive endocrinology practice. clinical diagnosis made if there history chronic anovulation association either evidence androgen excess...
Abstract Women with polycystic ovary syndrome (PCOS) exhibit an adverse cardiovascular risk profile, characteristic of the metabolic (MCS). The aim this study was to determine prevalence coronary artery (CAC) and aortic (AC) calcification among middle-aged PCOS cases controls explore relationship calcification, MCS, other factors assessed 9 yr earlier. This a prospective 61 85 similarly aged screened in 1993–1994 for reevaluated 2001–2002. main outcome measures were CAC AC, measured by...
Polycystic ovary syndrome (PCOS) presents in adolescence, and obesity is a common finding. The benefits risks of alternate approaches to the management PCOS obese adolescent women are not clear.We investigated effects metformin, oral contraceptives (OCs), and/or lifestyle modification with PCOS.Two small, randomized, placebo-controlled clinical trials were performed.A total 79 participated.In single treatment trial, subjects randomized placebo, program, or OC. In combined all received OC...
Abstract We investigated the effects of using intrapartum electronic fetal monitoring in all pregnancies, as compared with it only cases which fetus is judged to be at high risk. Predominant risk factors included oxytocin stimulation labor, dysfunctional abnormal heart rate, or meconium-stained amniotic fluid. This prospective alternate-month clinical trial took place over a 36-month period during 34,995 women gave birth. In alternate months, either 7 (for "selective monitoring") 19...
In Brief OBJECTIVE: To assess the effect of low-dose mifepristone on quality life, pain, bleeding, and uterine size among women with symptomatic leiomyomata. METHODS: Forty-two leiomyomata volume 160 mL or more were randomized to mifepristone, 5 mg daily, placebo for 26 weeks. Quality life (Uterine Fibroid Symptoms Life Questionnaire Medical Outcomes Study 36-Item Short Form survey) leiomyoma (ultrasonography) assessed at baseline, 1 month, 3 months, 6 months treatment. Bleeding (daily logs...
In Brief OBJECTIVE: To compare the efficacy of gabapentin, estrogen, and placebo in treatment hot flushes. METHODS: We performed a randomized, double-blind, placebo-controlled trial 60 postmenopausal women to assess estrogen gabapentin moderate-to-severe Participants were randomly assigned receive either 0.625 mg/d conjugated estrogens (n = 20), or titrated 2,400 20) for 12 weeks. recorded frequency severity baseline flushes on flush diary 2 weeks before randomization after randomization....
To compare the effect of 5 and 10 mg mifepristone on uterine leiomyoma size symptoms, to measure side effects.Forty premenopausal women with large, symptomatic leiomyomata were randomized receive either or daily for 6 months in an open-label study. Uterine volume was measured at bimonthly intervals by sonography. Serum concentrations hemoglobin levels, follicle-stimulating hormone, liver enzymes obtained, endometrial samples, menstrual bleeding also assessed.Nineteen 20 subjects taking all...
Context: Adults with polycystic ovary syndrome (PCOS) may be at increased risk for metabolic (MBS) and related cardiovascular disease. It is not clear whether PCOS diagnosed in adolescence increases the of MBS this age group. Objective: The aim was to compare prevalence characteristics obese adolescents without PCOS. Design: We conducted a cross-sectional study overweight BMI matched controls. Patients Participants: A total 74 subjects, 43 31 controls, participated study. Interventions: Each...
Cytologic screening for cervical cancer currently enjoys wide acceptance, but there remains controversy in the literature concerning its efficacy prolonging life. On basis of a review, several conclusions are reached: 1) Cervical can identify women who at greater-than-average risk developing invasive by detecting asymptomatic lesions that would frequently progress to invasion if left untreated; 2) Therapy based on confirmed positive smears reduce incidence and mortality rates cancer, as...