A5044024243- Organ and Tissue Transplantation Research
- Organ Donation and Transplantation
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Wound Healing and Treatments
- Burn Injury Management and Outcomes
- Frailty in Older Adults
- Facial Nerve Paralysis Treatment and Research
- Nasal Surgery and Airway Studies
- Bacterial biofilms and quorum sensing
- Facial Trauma and Fracture Management
- Traumatic Ocular and Foreign Body Injuries
- Health Systems, Economic Evaluations, Quality of Life
- Transplantation: Methods and Outcomes
- Nutrition and Health in Aging
- Injury Epidemiology and Prevention
- Nonmelanoma Skin Cancer Studies
- Body Image and Dysmorphia Studies
- Autopsy Techniques and Outcomes
- Surgical Simulation and Training
- Trauma Management and Diagnosis
- CRISPR and Genetic Engineering
- Breast Implant and Reconstruction
- Abdominal vascular conditions and treatments
- Biomedical Ethics and Regulation
Yale New Haven Hospital
2023-2025
Yale University
2023-2025
Barro Colorado Island
2024
University Hospital Münster
2022-2023
Witten/Herdecke University
2020
Purpose A major concern for patients undergoing facial transplantation relates to postoperative appearance. This study leverages artificial intelligence (AI) visual analysis software provide an objective assessment of perceived age and degree resemblance the donor. Methods Postoperative images 15 face transplant were analyzed by Visage Technologies Visage|SDK™ AI determine age. subgroup eight patients, which donor patient pretrauma photographs available, was using same percent similarity...
Biofilms pose a relevant factor for wound healing impairment in chronic wounds. With 78% of all wounds being affected by biofilms, research this area is high priority, especially since data evidence-based selection appropriate antimicrobials and antiseptics scarce. Therefore, the objective study was to evaluate anti-biofilm efficacy commercially available hypochlorous irrigation solutions compared established antimicrobials. Using an innovative complex in-vitro human plasma biofilm model...
Division of Plastic and Reconstructive Surgery, Yale School Medicine, New Haven, CT, USA Abbreviations: facial vascular composite allotransplantation (fVCA), quality life (QoL) Acknowledgements/Funding: None. Disclosures: The authors report no funding sources or conflict interest concerning the materials methods used in this study findings specified study. LH is receiving a Two-Year-Walter-Benjamin Fellowship by German Research Foundation (DFG). JZG One-Year Medical Student from Medicine...
The purpose of this study is to provide a comprehensive overview the epidemiology traumatic craniofacial injuries in U.S. that occur context drugs and/or alcohol. National Electronic Injury and Surveillance System (NEISS) database was queried from 2019 2022 identify all emergency department (ED) patients with reported involving anatomy. Clinical demographic variables were assessed between cases involved drugs/alcohol those did not, utilizing two-proportion z-tests. In total, 441,764...
Face transplant rejection is primarily monitored through skin biopsies, but mucosal tissue may detect immune events missed by biopsies. We retrospectively reviewed 47 paired and facial biopsies 37 sentinel flap from nine face recipients. Rejection was graded using the 2007 Banff classification. Correlation, sensitivity, specificity metrics were assessed. Mucosa grades correlated strongly (r = 0.72, p < 0.0001), with mucosa showing a negative predictive value (NPV) of 0.85 for rejection....
Rejection represents a major and common complication in vascularized composite allotransplantation (VCA). Over time, recurrent acute or chronic rejection can lead to vascular dermal fibrosis potentially graft loss. To date, non-invasive monitoring tool capture changes among VCA recipients has not been established. This pilot study aims assess the potential value of noninvasive skin elasticity measurements for surveillance longitudinal facial allografts. Viscoelasticity was non-invasively...