- Acute Ischemic Stroke Management
- EEG and Brain-Computer Interfaces
- Dementia and Cognitive Impairment Research
- Epilepsy research and treatment
- Stroke Rehabilitation and Recovery
- Blind Source Separation Techniques
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Long-Term Effects of COVID-19
- Parkinson's Disease Mechanisms and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Heart Rate Variability and Autonomic Control
- Peripheral Neuropathies and Disorders
- Migraine and Headache Studies
- Autoimmune Neurological Disorders and Treatments
- Health disparities and outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disease Mechanisms and Treatments
- COVID-19 and healthcare impacts
- Global Public Health Policies and Epidemiology
- Cardiovascular Health and Risk Factors
- Pharmacological Effects and Toxicity Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- ECG Monitoring and Analysis
- Balance, Gait, and Falls Prevention
Government Medical College
2015-2025
Health Action by People
2020-2024
Sri Ramachandra Institute of Higher Education and Research
2023-2024
University Hospital of Bern
2024
University of Bern
2024
Government Medical College
2011-2023
ICMR-National Institute of Virology
2023
Monash University Malaysia
2023
Nizam's Institute of Medical Sciences
2022
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2022
To assess the prevalence and factors associated with mild cognitive impairment (MCI) among older adults in an urban area of South India.The study was conducted capital city Thiruvananthapuram Indian state Kerala.The participants were community-dwelling individuals aged 60 years above.MCI primary outcome measure defined using criteria by European Alzheimer's Disease Consortium. Cognitive assessment done Malayalam version Addenbrooke's Examination tool. Data also collected on sociodemographic...
Abstract Aims To compare the prevalence of electrocardiogram (ECG)-documented atrial fibrillation (or flutter) (AF) across eight regions world, and to examine antithrombotic use clinical outcomes. Methods results Baseline ECGs were collected in 153 152 middle-aged participants (ages 35–70 years) document AF two community-based studies, spanning 20 countries. Medication outcome data (mean follow-up 7.4 available one cohort. Cross-sectional analyses performed medication use, associations...
OBJECTIVE We aimed to compare cardiovascular (CV) events, all-cause mortality, and CV mortality rates among adults with without diabetes in countries differing levels of income. RESEARCH DESIGN AND METHODS The Prospective Urban Rural Epidemiology (PURE) study enrolled 143,567 aged 35–70 years from 4 high-income (HIC), 12 middle-income (MIC), 5 low-income (LIC). mean follow-up was 9.0 ± 3.0 years. RESULTS Among those diabetes, CVD (LIC 10.3, MIC 9.2, HIC 8.3 per 1,000 person-years, P <...
The number of older people with cognitive impairment being seen in out patient settings is increasing. A brief screening test, which culturally and educationally fair, would be very useful for clinicians identifying dementia these settings.To examine the new Rowland Universal Dementia Assessment Scale (RUDAS), to compare it Mini-Mental State Examination (MMSE).We administered MMSE RUDAS 116 subjects, consisting 58 patients mild moderate age sex matched controls. two tests were compared...
EEG analysis in the field of neurology is customarily done using frequency domain methods like fast Fourier transform. A complex biomedical signal such as best analysed a time-frequency algorithm. Wavelet decomposition based relatively novel area and for extracting its subbands. This work aims at exploring use discrete wavelet transform subbands encephalopathy. The subband energies were then calculated given feature sets to SVM classifier identifying cases encephalopathy from normal healthy...
To determine whether cognitive reserve attenuates the association of vascular brain injury with cognition.Cross-sectional data were analyzed from 2 harmonized studies: Canadian Alliance for Healthy Hearts and Minds (CAHHM) Prospective Urban Rural Epidemiology (PURE) study. Markers education, involvement in social activities, marital status, height, leisure physical activity, which combined into a composite score. Vascular was defined as nonlacunar infarcts or high white matter hyperintensity...
There are only very few studies on estimating the prevalence of mild cognitive impairment (MCI) from India, particularly a rural setting. The available were heterogeneous.The study estimated MCI in setting Kerala, India.We conducted community-based, cross-sectional among individuals aged 65 and above Thiruvananthapuram, Kerala. A cluster-randomized sampling was adopted, cluster being wards village. It two-phase door-to-door survey. Grassroots-level health workers enrolled 366 elders selected...
Background: Meningeal tuberculosis (TB) has higher mortality compared to other forms of central nervous system TB. However, data on predictors is limited. Aims: To determine the in patients with meningeal Materials and Methods: This study retrospectively analyzed admitted a diagnosis TB between January 2006 December 2008. Thwaites' index score four or less was used for which weighted diagnostic dichotomised clinical variables. Predictors were separately both human immunodeficiency virus...
Aseptic meningitis is characterized by noninfective serous inflammation of the meninges. It can occur in a recurrent fashion when associated with dermoid and epidermoid cysts due to rupture cyst contents into subarachnoid space resulting aseptic chemical meningitis. Bacterial association these tumors commonly related coexisting dermal sinus tract most common organism Staphylococcus aureus.
EEG contains immense information about the brain activity which cannot be understood completely by visual inspection. Powerful signal processing algorithms in analysis can greatly assist physicians and neurologists to extract such hidden information. It has been found that being a time-varying non-stationary signal, analyzed non-linear methods. In this paper we tried evaluate non linear features like Approximate Entropy, Sample Entropy Hurst Exponent epileptic normal obtained clear...
The role of variables like duration diabetes, diabetic control and microvascular complications in the causation cognitive decline patients with type 2 diabetes is not well studied. contribution hypertension to nondemented unclear.We wanted see if cognition associated vascular risk factors, or depression. We also looked at association noncompliance cognition, depression.We recruited ambulant who are 55 years more age from weekly clinic. excluded past history stroke.We selected time taken for...
Intravenous thrombolysis is an effective treatment of acute ischemic stroke but has a narrow therapeutic time window 3-4.5 h. Pre-hospital delay major barrier to patients becoming eligible for thrombolysis. This single-center study assessed the factors causing longer onset-to-door (OTD) identify measures that will help decrease delay.
This review is on ultrastructure and subcellular physiology at normal abnormal neuromuscular junctions. The clinical electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS), congenital syndromes, botulinum intoxication are discussed. Single fiber electromyography (SFEMG) helps to explain the basis of testing junction function by repetitive nerve stimulation (RNS). SFEMG requires skill patience its availability limited a few centers. For RNS supramaximal...
Chaotic analysis is a relatively novel area in the study of physiological signals. features electroencephalogram have been analyzed various disease states like epilepsy, Alzheimer’s disease, sleep disorders, and depression. All these diseases primary involvement brain. Our examines chaotic parameters metabolic encephalopathy, where brain functions are involved secondary to disturbance. clearly showed significant lower values for parameters, correlation dimension, largest Lyapunov exponent...
Airplane travel headache is rare and has recently been described as a new form of associated with specific situation. Of the 1,208 patients primary headaches attending tertiary care neurology hospital, two (0.16%) satisfied criteria for related to airplane travel. Both fulfilled proposed diagnostic headache. This unique had mean duration 24 minutes, localized medial supraorbital region having an intense jabbing or stabbing character that occurred exclusively maximally during aircraft landing...