- Monoclonal and Polyclonal Antibodies Research
- Economic and Financial Impacts of Cancer
- Advances in Oncology and Radiotherapy
- Virus-based gene therapy research
- Glycosylation and Glycoproteins Research
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Testicular diseases and treatments
- Nutrition, Genetics, and Disease
- Radiopharmaceutical Chemistry and Applications
- BRCA gene mutations in cancer
- HER2/EGFR in Cancer Research
- Neuroblastoma Research and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Science, Research, and Medicine
- Lung Cancer Treatments and Mutations
- Cancer Research and Treatments
- Advanced Breast Cancer Therapies
- Prostate Cancer Treatment and Research
- Sexual Differentiation and Disorders
- Immunotherapy and Immune Responses
- RNA Interference and Gene Delivery
- Genetics, Bioinformatics, and Biomedical Research
- Genetic factors in colorectal cancer
- Sarcoma Diagnosis and Treatment
University of Buckingham
2005-2024
Hammersmith Hospital
2003-2022
London Cancer
2006-2020
Proton (United Kingdom)
2018
University of Economy in Bydgoszcz
2016
Ludwig Cancer Research
1981-2015
Imperial College London
1999-2008
Prostate Cancer UK
2006-2007
Medical Solutions
2004-2005
AstraZeneca (United Kingdom)
2003
IN laboratory animals both endogenously induced and passively administered interferon have inhibitory effects on a wide variety of tumors, including those caused by oncogenic viruses.1 2 3 4 Such are most striking when the is prophylactically, but has occasionally been observed to therapeutic effects. In latter situation, its continued administration appears required for maintenance beneficial effect. Studies Strander his associates at Karolinska Hospital in solid particularly osteogenic...
Ten women with advanced locally recurrent breast cancer who had failed to respond radiation and hormonal cytotoxic agents were given up 12 weeks of recombinant leucocyte interferon 20 X 10(6) U/m2 daily or 50 three times a week. Within one hour administration influenza-like symptoms began, which week later superseded by lethargy, anorexia, nausea, consequent loss weight in most patients. Other side effects included profound somnolence, confusion, paraesthesia, (in patient) signs an upper...
The pattern of c-myc gene organization and expression has been examined in resected colonic tumors the adjacent normal colon from 15 patients undergoing radical surgery. DNA hybridization showed no evidence amplification or rearrangement. Transcripts messenger ribonucleic acid (mRNA) were elevated up to 32-fold 12 tumors. product, p62c-myc, was detected by both immunoblotting immunohistology using a monoclonal antibody raised against synthetic peptide immunogen. There close correlation...
PURPOSE: This trial was designed to test the safety and efficacy of a tumor-specific genetic prodrug activation therapy targeted by use human erbB-2 gene promoter. The oncogene is overexpressed in approximately 20% cases breast cancer associated with poor prognosis. PATIENTS AND METHODS: Twelve patients received transcriptionally phase I clinical using direct intratumoral injection plasmid construct combined systemic administration prodrug. specifically erbB-2–overexpressing cells...
Most government efforts to control the COVID-19 pandemic revolved around non-pharmaceutical interventions (NPIs) and vaccination. However, many respiratory diseases show distinctive seasonal trends. In this manuscript, we examined contribution of these three factors progression pandemic.