A5107657582- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Blood properties and coagulation
- Primary Care and Health Outcomes
- Mobile Health and mHealth Applications
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Pharmaceutical Practices and Patient Outcomes
- Diabetes Treatment and Management
- Microbial bioremediation and biosurfactants
- Cardiac electrophysiology and arrhythmias
- Nitric Oxide and Endothelin Effects
- Diabetes and associated disorders
- Heart Rate Variability and Autonomic Control
- Diabetes Management and Research
- Microbial Metabolic Engineering and Bioproduction
- Medication Adherence and Compliance
- Reproductive Health and Contraception
- Lymphatic System and Diseases
- Simulation-Based Education in Healthcare
- Mental Health and Patient Involvement
- Mesenchymal stem cell research
- Inflammatory mediators and NSAID effects
- Protein Hydrolysis and Bioactive Peptides
- Protein Interaction Studies and Fluorescence Analysis
University College London
2012-2023
Royal Brisbane and Women's Hospital
2023
Queens University
2022
University College Lillebaelt
2022
Imperial College London
2012-2021
Australian Bureau of Statistics
2021
Gulf Medical University
2020
University of Central Florida
2007-2017
University of London
1993-2011
Seminole State College of Florida
2011
Background Diabetes costs represent a large burden to both patients and the health care system. However, few studies that examine economic consequences of diabetes have distinguished between two major forms, type 1 2 diabetes, despite differences in underlying pathologies. Combining diseases implies there is no difference patient. In this study, we which often overlooked due larger population patients, compare them estimated reported literature. Methodology/Principal Findings Using...
Rare diseases are an important public health issue with high unmet need. The introduction of the EU Regulation on orphan medicinal products (OMP) has been successful in stimulating investment research and development OMPs. Despite this advancement, patients do not have universal access to these new medicines. There many factors that affect OMP uptake, but one most is difficulty making pricing reimbursement (P&R) decisions rare diseases. Until now, there little consensus appropriate...
Abstract Despite rapid advances in the stem cell field, ability to identify and track transplanted or migrating cells vivo is limited. To overcome this limitation, we used magnetic resonance imaging (MRI) detect follow over a period of 28 days mice using an established myocardial infarction model. Pluripotent mouse embryonic (mES) were expanded induced differentiate into beating cardiomyocytes vitro. The cardiac-differentiated mES then loaded with superparamagnetic fluorescent microspheres...
Government and professional groups within the pharmacy have sought to extend role of pharmacists from dispensing-focused towards provision further pharmaceutical services. The aim this research was describe how in current English community practice spend their time using a work sampling method.Ten pharmacies across London were purposively selected. Trained observers visited one each record activities responsible pharmacist, fixed-interval technique. Activities recorded every minute, into 18...
Previously, Pseudomonas putida was shown to degrade (+)-camphor, and cleavage of the first ring bicyclic structure involved two monooxygenases (a hydroxylase a oxygen-inserting enzyme), dehydrogenase, spontaneous an unstable oxygenation product (lactone). Cleavage second not demonstrated but assumed also occur by oxygen insertion, since predicted extracted from whole-cell incubation systems. Our investigation established that metabolism intermediate, 2-oxo-delta...
Thirty-three microorganisms capable of growth with cyclohexane carboxylate as the sole source carbon were isolated from mud, water, and soil samples Aberystwyth area. Preliminary screening whole-cell oxidation studies suggested that, one exception, all strains metabolized substrate by beta-oxidation coenzyme A ester. This single distinctive strain, able to oxidize rapidly trans -4-hydroxycyclohexane carboxylate, 4-ketocyclohexane p -hydroxybenzoate, protocatechuate when grown was classified...
Abstract Background Within the United Kingdom’s National Health System (NHS), patients suffering from obesity may be provided with bariatric surgery. After receiving surgery many of these require further support to continue lose more weight or maintain a healthy weight. Remotely monitoring such patients’ physical activity and other health-related variables could provide healthworkers ‘ecologically valid’ picture behaviours then personalised support. The current study assesses feasibility two...
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a long-term progressive inflammatory lung disease causing chronic breathlessness and many hospital admissions. It affects up to 1.2 million people in the UK. To help with COPD self-manage their condition we developed, partnership healthcare users, digital mobile phone app called COPD.Pal®. We report first user feedback of COPD.Pal®, applying Technology Acceptance Model (TAM) theoretical framework. 11 participants engaged click dummy...
The diabetogenic effects of alloxan (50 mg/kg i.v.) were recorded for 6 weeks in normotensive (WKY) and spontaneously hypertensive (SHR) rats. While systolic blood pressure increased diabetic WKY, SHR exhibited a reduction over the 6-week period. Heart rate treated SHR, but not was reduced significantly during course diabetes. postalloxan, pressor responses to spinal cord stimulation various vasoactive agents both groups as compared their age-matched controls. However, vitro preparations...
Stem cell therapies offer the potential for repair and regeneration of cardiac tissue. To facilitate evaluation stem activity in vivo, we created novel dual-reporter mouse embryonic (mES) lines that express firefly luciferase (LUC) reporter gene under control sodium–calcium exchanger-1 (Ncx-1) promoter background 7AC5-EYFP mES line constitutively expresses enhanced yellow fluorescent protein (EYFP). We compared ability recombinant clonal to LUC before after induction differentiation vitro....