A5079037628- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Adolescent and Pediatric Healthcare
- Inflammatory Myopathies and Dermatomyositis
- Childhood Cancer Survivors' Quality of Life
- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Streptococcal Infections and Treatments
- Immunodeficiency and Autoimmune Disorders
- Inflammasome and immune disorders
- Rheumatoid Arthritis Research and Therapies
- Systemic Sclerosis and Related Diseases
- Dermatological and Skeletal Disorders
- Ocular Diseases and Behçet’s Syndrome
- Hematological disorders and diagnostics
- Eosinophilic Disorders and Syndromes
- Bone health and treatments
- Musculoskeletal Disorders and Rehabilitation
- Hemoglobinopathies and Related Disorders
- Acute Lymphoblastic Leukemia research
- Chronic Lymphocytic Leukemia Research
- Spondyloarthritis Studies and Treatments
- Eosinophilic Esophagitis
- Otitis Media and Relapsing Polychondritis
- Whipple's Disease and Interleukins
Universidade Federal de Ciências da Saúde de Porto Alegre
2019-2021
Rafael Advanced Defense Systems (Israel)
2019
Universidade Federal de São Paulo
2008-2018
Santa Casa de Misericórdia de Marília
2017
Irmandade da Santa Casa de Misericórdia de São Paulo
2017
Fundação de Apoio à Universidade Federal de São Paulo
2003-2013
Universidade de São Paulo
2004-2009
Charles University
2004
Hospital Universitario La Paz
2004
Cornell University
2004
<h3>Objectives</h3> To validate the previously proposed classification criteria for Henoch–Schönlein purpura (HSP), childhood polyarteritis nodosa (c-PAN), c-Wegener granulomatosis (c-WG) and c-Takayasu arteritis (c-TA). <h3>Methods</h3> Step 1: retrospective/prospective web-data collection children with HSP, c-PAN, c-WG c-TA age at diagnosis ≤18 years. 2: blinded by consensus panel of a representative sample 280 cases. 3: statistical (sensitivity, specificity, area under curve κ-agreement)...
Objective. Juvenile localized scleroderma (JLS) includes a number of conditions often grouped together. With the long-term goal developing uniform classification criteria, we studied epidemiological, clinical and immunological features children with JLS followed by paediatric rheumatology dermatology centres.
OBJETIVOS: Avaliar a confiabilidade e validade da versão brasileira do questionário genérico Pediatric Quality of Life InventoryTM (PedsQL TM 4.0) mensurar qualidade de vida crianças adolescentes saudáveis pacientes com doenças reumáticas. MÉTODOS: No processo validação, seguimos metodologia proposta pelos idealizadores original em inglês PedsQL 4.0. O instrumento foi administrado por entrevista dois grupos: 240 aparentemente São Paulo (SP) 105 reumáticas crônicas, pareados idade, aos...
Systemic juvenile idiopathic arthritis (sJIA) is an often severe, potentially life-threatening childhood inflammatory disease, the pathophysiology of which poorly understood. To determine whether genetic variation within MHC locus on chromosome 6 influences sJIA susceptibility, we performed association study 982 children with and 8,010 healthy control subjects from nine countries. Using meta-analysis directly observed imputed SNP genotypes classic HLA types, identified as a bona fide...
Objectives Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified by the presence chronic childhood without an identifiable cause. Systemic JIA (sJIA) rare form characterised systemic inflammation. sJIA distinguished from other forms unique clinical features and treatment responses that are similar to autoinflammatory diseases. However, approximately half children with develop destructive, long-standing appears JIA. Using genomic approaches, we sought gain novel...
CONTEXTO: A autopercepção e a satisfação com imagem corporal são fatores preponderantes na auto-aceitação do adolescente podem gerar atitudes inadequadas que prejudicam seu crescimento desenvolvimento. OBJETIVO: Relacionar o estado nutricional percepção da tem de si próprio. MÉTODOS: informação índice massa (IMC) foi obtida por dados antropométricos para classificar nutricional. Utilizaram-se silhuetas padronizadas avaliar um questionário autopreenchimento determinar corporal. RESULTADOS:...
Sera from 214 healthy children and adolescents (108 females [50.4%]) aged 6 months to 20 years (mean 8.7 years) 116 patients with rheumatic diseases were assayed for antinuclear antibody (ANA) by indirect immunofluorescence (IIF) using HEp-2 cells as substrate. Twenty-seven (12.6%) presented a positive ANA test; there was no difference between genders, we observed trend higher frequency of ≥1/80 among 5 10 years. Eight the 27 test reevaluated 36 later, none them had developed any disease,...
To evaluate the quality of life in children and adolescents with sickle cell disease attending a blood reference center, to assess their relatives.Cross-sectional study that included 100 patients disease, which were divided into three subgroups according age: 5 7 (n=18), 8 12 (n=32), 13 18 years-old (n=50), parents. The Control Group 50 healthy from public local school, also same age caregivers. Pediatric Quality Inventory (PedsQL), version 4.0, was applied both groups. generic questionnaire...
Musculoskeletal complaints may be associated with neoplasias as an initial manifestation of the disease. When these symptoms predominate at onset disease, differential diagnosis includes several rheumatic diseases.To assess frequency, clinical features and types cancer manifested in children presenting musculoskeletal over a seven-year period.Retrospective.Discipline Allergy, Clinical Immunology Rheumatology, Universidade Federal de São Paulo-Escola Paulista Medicina.The medical records...
We evaluated the prevalence and clinical associations of amenorrhea in 298 female juvenile systemic lupus erythematosus (JSLE) patients (ACR criteria) followed 12 Brazilian Paediatric Rheumatology centres. Amenorrhea was observed 35 (11.7%) with a mean duration 7.2 ± 3.6 months. The hormones were performed 32/35 none them had FSH LH levels above estradiol below normal range according to pubertal changes. JSLE younger (15.04 2.5 versus 17.8 3.1 years; P = 0.001), shorter period time between...
OBJETIVOS: Avaliar o consumo alimentar de crianças e adolescentes com artrite idiopática juvenil (AIJ) lúpus eritematoso sistêmico (LES) por recordatório 24 horas relacioná-lo características clínicas antropométricas os medicamentos empregados. MÉTODOS: Em estudo transversal, avaliamos recordatórios pacientes ambulatoriais. O estado nutricional foi classificado pelo CDC, 2000. Para cálculo da ingestão, utilizamos software NutWin UNIFESP-EPM. a análise quantitativa qualitativa, adotamos as...