Kewei Zhang

ORCID: 0000-0003-4871-2261
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About
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Research Areas
  • Aortic aneurysm repair treatments
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Traditional Chinese Medicine Analysis
  • Aortic Disease and Treatment Approaches
  • Peripheral Artery Disease Management
  • Traditional Chinese Medicine Studies
  • Pregnancy and preeclampsia studies
  • Infectious Aortic and Vascular Conditions
  • Venous Thromboembolism Diagnosis and Management
  • Organ Transplantation Techniques and Outcomes
  • Neurological Disease Mechanisms and Treatments
  • Respiratory viral infections research
  • Cystic Fibrosis Research Advances
  • Pediatric health and respiratory diseases
  • Renal and Vascular Pathologies
  • Renal Diseases and Glomerulopathies
  • Abdominal vascular conditions and treatments
  • Pharmacological Effects of Medicinal Plants
  • Bone Metabolism and Diseases
  • Titanium Alloys Microstructure and Properties
  • Cerebrovascular and Carotid Artery Diseases
  • Ginkgo biloba and Cashew Applications
  • Drug Transport and Resistance Mechanisms
  • Reproductive System and Pregnancy

Qinghai University Affiliated Hospital
2019-2024

Nanjing University of Chinese Medicine
2016-2024

University of Southampton
2023-2024

University Hospital Southampton NHS Foundation Trust
2024

Nanjing Medical University
2024

Jiangsu Province Hospital
2024

Henan Provincial People's Hospital
2015-2023

Zhengzhou University
2015-2023

Westmead Institute
2018-2023

Westmead Hospital
2018-2023

Dietary habits are crucial in the progression of hepatic lipid accumulation and nonalcoholic fatty liver disease (NAFLD). However, there limited studies using ¹H-magnetic resonance spectroscopy (¹H-MRS) dual-echo in-phase out-phase magnetic imaging (dual-echo MRI) to assess effects dietary nutrient intakes on contents. In present study, we recruited 36 female adults (NAFLD:control = 19:17) receive questionnaires medical examinations, including intakes, anthropometric biochemical...

10.3390/nu8090527 article EN cc-by Nutrients 2016-08-27

The aim of the present study was to identify abdominal aortic aneurysms (AAA)-associated miR-155 contributing AAA pathology by regulating macrophage-mediated inflammation. Angiotensin II (AngII)–infused apolipoprotein E-deficient (ApoE-/-) mice and THP-1 cells model overexpression deficiency were used in experiments. expression detected quantitative reverse transcription polymerase chain reaction (qRT-PCR). Cytokines evaluated using enzyme-linked immunoabsorbent assay (ELISA). Western...

10.1042/bsr20171432 article EN Bioscience Reports 2018-02-20

Traditional fibrous membranes employed in guided tissue regeneration (GTR) the treatment of periodontitis have limitations bioactive and immunomodulatory properties. We fabricated a novel nTPG/PLGA/PCL membrane by electrospinning which exhibit excellent hydrophilicity, mechanical properties biocompatibility. In addition, we investigated its regulatory effect on polarization macrophages facilitating periodontal both vivo vitro. These findings showed 0.5%TPG/PLGA/PCL may inhibit RAW 264.7 into...

10.1016/j.mtbio.2024.101036 article EN cc-by-nc Materials Today Bio 2024-04-02

The AngioJet rheolytic thrombectomy (ART) system can quickly fragment and aspirate thrombi according to Bernoulli's principle.This retrospective study aimed evaluate the therapeutic effects of ART in treating severe acute pulmonary embolism (APE), including high-risk (HR-PE) intermediate-high-risk (IHR-PE).Forty-four APE patients (21 HR-PE 23 IHR-PE) were enrolled underwent using 6 Fr Solent Omni device. Nineteen diagnosed with lower extremity deep venous thrombosis (LEDVT), LEDVT...

10.4244/eij-d-20-00259 article EN EuroIntervention 2021-06-01

Background The extent to which changes in lung function are due natural variability patients with primary ciliary dyskinesia (PCD) is unknown. We aimed assess intra-individual forced expiratory volume 1 s (FEV ) derived from spirometry define the observed were test clinically stable PCD patients. Methods PROVALF-PCD a large international prospective cohort conducted 2017–2019. included ≥5 years who ≥2 consecutive visits and provided spirometry-derived measurements. To calculate upper limit...

10.1183/23120541.01115-2024 article EN cc-by-nc ERJ Open Research 2025-03-28

The present study investigated the incidence, causes, treatment and prevention of limb graft occlusion following endovascular aortic repair (EVAR). A total 66 cases abdominal aneurysm receiving EVAR at our department from January 2005 to December 2013 were enrolled. After EVAR, patients received routine antiplatelet therapy 75 mg PLAVIX for 6 months then 100 Aspirin another by oral administration. According previous clinical experiences, is able effectively reduce incidence iliac after EVAR....

10.3892/etm.2017.4658 article EN Experimental and Therapeutic Medicine 2017-06-23

There is a lack of information on the epidemiological data and risk factors associated with abdominal aortic aneurysm (AAA) in Chinese population. We reported primary results from screening five-community population Middle China for AAA. From March 2014 to October 2015, an AAA program was performed three urban two rural communities. These communities were randomly selected. All at-risk residents (a total 6925) aged 40 years or older invited attend ultrasound scan At-risk defined as having...

10.1186/s12872-018-0793-5 article EN cc-by BMC Cardiovascular Disorders 2018-04-03

Background: Glioblastoma multiforme (GBM) is the most common malignant and lethal type of primary central nervous system tumor in humans. In spite its high lethality, a small percentage patients have relatively good prognosis, with median survival times 36 months or longer. The identification clinical subsets GBM associated distinct molecular genetic profiles has made it possible to design therapies tailored treat individual patients. Methods: We compared microarray data sets from long-term...

10.2147/ott.s117165 article EN OncoTargets and Therapy 2017-01-01

To localize, quantify and compare angiogenic factors, vascular endothelial growth factor (VEGF), placental (PlGF), as well their receptors fms-like tyrosine kinase receptor (Flt-1) insert domain (KDR) in the placentas of normal pregnancy complications preeclampsia (PE), intrauterine fetal restriction (IUGR) PE + IUGR.In a prospective cross-sectional case-control study, 30 pregnant women between 24-40 weeks gestation, were recruited into four clinical groups. Representative samples stained...

10.1111/jog.13592 article EN Journal of Obstetrics and Gynaecology Research 2018-02-01

OBJECTIVE To determine the correlation between urinary and serum placental growth factor (PlGF) investigate predictive value as pregnancy progresses of PlGF compared with PlGF, soluble fms-like tyrosine kinase 1 (sFLT-1), sFLT-1–to–PlGF ratio for outcome preeclampsia in women preexisting diabetes. RESEARCH DESIGN AND METHODS A multicenter prospective cohort study was conducted 158 insulin-requiring diabetes (41 type 117 2). Urinary sFLT-1, were assessed four times (14, 24, 30, 36 weeks’...

10.2337/dc19-0967 article EN Diabetes Care 2019-10-10

Interleukin‑6 (IL‑6) is involved in various biological responses, including tumor progression, metastasis and chemoresistance. However, the role molecular mechanism of IL‑6 treatment sorafenib liver cancer remain unclear. In present study, through western blot analysis, Transwell assay, flow cytometric ELISA analysis immunohistochemistry it was revealed that promoted induced epithelial‑mesenchymal transition (EMT) cells vitro vivo, significantly increased expression. Endogenous or exogenous...

10.3892/or.2021.7926 article EN cc-by-nc-nd Oncology Reports 2021-01-07

Normal adult mammary stem cells (AMSCs) are promising sources for breast reconstruction, particularly following the resection of tumors. However, carcinogenic events can potentially convert normal AMSCs to cancer cells, posing a safety concern use clinical tissue regeneration. In present study, and autologous primary were isolated compared their ability differentiate, gene expression profile, potential form tumors in vivo. from surrounding by immunomagnetic sorting. The pluripotency these...

10.3892/ol.2017.6485 article EN Oncology Letters 2017-06-28

Abstract Aim To correlate plasma and urinary soluble fms‐like tyrosine kinase 1 (sFlt‐1) placental growth factor (PIGF) in preeclampsia (PE) fetal restriction (FGR) assess the performance detecting established disease. Methods A cross‐sectional case–control study recruited 26–40 weeks gestation pregnancies into four clinical groups: normal pregnancy, PE, PE + FGR, FGR. enzyme‐linked immunosorbent assay (ELISA) measurements of sFlt‐1 PlGF levels were performed. Urinary PIGF normalized to...

10.1111/jog.14038 article EN Journal of Obstetrics and Gynaecology Research 2019-07-01

Objective This article aims to investigate the incidence rate of retrograde type A aortic dissection (RTAD) and risk factors RTAD in relation thoracic endovascular repair (TEVAR). Methods Patients with disease who underwent TEVAR at Henan Provincial People's Hospital from January 2004 December 2019 were enrolled present research. The associated following using univariate multiple logistic regression analyses. Results During study period, total 1,688 patients included this study, these, 1,592...

10.3389/fcvm.2023.1160142 article EN cc-by Frontiers in Cardiovascular Medicine 2023-07-21

Fructus Gardeniae, known as Zhi-zi in China, has been used Chinese herbal medicine and functional health food for thousands of years. Gardeniae Grandiflorae, named Shui-zhizi, is a counterfeit herb Gardeniae. In order to discriminate these two varieties, based on ultra-high-performance liquid chromatography, an analysis method fingerprints Grandiflorae was established. With hierarchical clustering principal component analysis, they were separated into groups. Analyzed with partial least...

10.1093/chromsci/bmab006 article EN Journal of Chromatographic Science 2021-01-18
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