- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Cerebrovascular and genetic disorders
- Aortic Disease and Treatment Approaches
- MicroRNA in disease regulation
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
Chinese PLA General Hospital
2022-2023
Anhui Medical University
2022-2023
State Council of the People's Republic of China
2023
Chinese People's Liberation Army
2022
Wenzhou Medical University
2022
Abstract Background The age of glioma plays a unique role in prognosis. We hypothesized that is not positively correlated with survival prognosis and explored its exact relationship. Methods Glioma was identified from the SEER database (between 2000 2018). A multivariate Cox proportional regression model restricted cubic spline (RCS) plot were used to assess relationship between Results total 66465 patients included. Hazard ratios (HR) for ten-year by age: 0–9 years, HR 1.06 (0.93–1.20);...
The influence of hypoperfusion on cognition in patients with Moyamoya disease (MMD) is unclear. This study investigated cognitive function changes MMD without stroke and illustrated the relationship between impairment hypoperfusion. We prospectively performed a structured battery seven neurocognitive tests 115 adult 82 healthy controls. Hemodynamic assessment was using dynamic susceptibility contrast-enhanced MRI. best subset regression (BSR) strategy used to identify risk factors. Global...
Background Little is known about the association between stroke and imaging clinical features in conservatively treated patients with moyamoya disease (MMD). Purpose To investigate independent risk factors for MMD during a long‐term follow‐up. Study Type Prospective study. Subjects One hundred sixty managed (median age 46 years, 89 male). Field Strength/Sequence Time of flight, turbo inversion recovery magnitude T1WI, spin echo (TSE) T2WI, echo‐planar DWI, T2‐fluid attenuated recovery,...
3D pseudo-continuous arterial spin labeling (3D pCASL) is commonly used to measure cerebral blood flow (CBF). The aim of this study was assess the clinical feasibility and accuracy pCASL in comparison with dynamic susceptibility contrast (DSC) perfusion imaging moyamoya disease (MMD).A total 174 MMD patients underwent DSC-MRI for evaluating perfusion. 3D-pCASL two single post-labeling delay (PLD) times (1,500 2,500 ms) CBF. values DSC-CBF ASL-CBF were calculated major territories including...
This study aimed to identify the high-resolution magnetic resonance imaging (HRMRI) features of moyamoya disease (MMD) patients with anterior intracerebral hemorrhage (ICH) and attempted reveal potential mechanisms ICH. Eligible adult MMD were consecutively included, morphological lenticulostriate arteries (LSAs), vessel wall structure terminal internal carotid artery (ICA) periventricular anastomosis evaluated by HRMRI. 78 containing 21 ICH, 31 ischemic 26 asymptomatic included. The mean...
The natural course and risk factors of moyamoya disease (MMD) associated with unruptured intracranial aneurysms involving stenosed parental arteries are scarcely studied. This study aimed to elucidate the MMD its in patients aneurysms.Between September 2006 October 2021, at our center were examined. course, clinical features, radiological follow-up outcomes after revascularization analyzed.This included 42 (42 aneurysms). age distribution cases ranged from 6 69 years, four children (9.5%) 38...
Background: The aetiology and natural course of moyamoya disease (MMD) remains unknown. Thus, this study evaluated the MMD using data from Chinese cohort (C-MMD) study.Method: C-MMD consisted 6,167 patients with treated at our centre over past 20 years. We analysed their medical history laboratory imaging examination results different stages to identify common features MMD.Findings: median age for symptom onset was 32 distribution bimodal; highest peak between ages 35 45 years, a smaller 3 9...
Abstract Background The etiology and natural course of moyamoya disease (MMD) remain unknown. This study evaluated the MMD using data from Chinese (C-MMD) cohort study. Methods C-MMD consisted 6,167 patients with treated at our center over past 20 years. We analyzed medical history laboratory imaging examination results different stages to identify common features MMD. Results median age for symptom onset was 32 distribution bimodal; highest peak between ages 35 45 years, a smaller 3 9...
Abstract Background : The etiology and natural course of moyamoya disease (MMD) remain unknown. This study evaluated the MMD using data from Chinese (C-MMD) cohort study. Methods C-MMD consisted 6,167 patients with treated at our center over past 20 years. We analyzed medical history laboratory imaging examination results different stages to identify common features MMD. Results median age for symptom onset was 32 distribution bimodal; highest peak between ages 35 45 years, a smaller 3 9...
Abstract Background Intracranial vessel wall enhancement (VWE) on high-resolution magnetic resonance imaging (HRMRI) is associated with the progression and poor prognosis of moyamoya disease (MMD). However, genetic background risk factors for VWE in MMD have not been investigated. Therefore, this study assessed potential MMD. Methods We evaluated patients using HRMRI traditional angiography examinations. The participants were divided into group non-VWE based presence or absence HRMRI....