Brigid Hooban

ORCID: 0000-0003-4882-6891
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About
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Research Areas
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Antibiotic Use and Resistance
  • Fecal contamination and water quality
  • Viral gastroenteritis research and epidemiology
  • Escherichia coli research studies
  • Child Nutrition and Water Access

Ollscoil na Gaillimhe – University of Galway
2019-2024

Water bodies worldwide have proven to be vast reservoirs of clinically significant antibiotic resistant organisms. Contamination waters by anthropogenic discharges is a contributor the widespread dissemination resistance. The aim this research was investigate multiple different sources on national scale for role they play in environmental propagation A total 39 water and 25 sewage samples were collected across four local authority areas West, East South Ireland. In total, 211...

10.1016/j.envint.2021.106466 article EN cc-by-nc-nd Environment International 2021-03-09

The natural environment represents a complex reservoir of antibiotic-resistant bacteria as consequence different wastewater discharges including anthropogenic and agricultural. Therefore, the aim this study was to examine sewage waters across Ireland for presence Enterobacterales. Samples were collected from West, East South Ireland. Two periods sampling took place between July 2019 November 2020, during which 118 water (30 L) 36 samples (200 mL) collected. Waters filtered using CapE method,...

10.1016/j.scitotenv.2022.154488 article EN cc-by The Science of The Total Environment 2022-03-09

Globally, water-based bathing pastimes are important for both mental and physical health. However, exposure to waterborne organisms could present a substantial public health issue. Bathing waters shown contribute the transmission of illness disease represent reservoir pathway dissemination antimicrobial resistant (AMR) organisms. Current water quality regulations focus on enumeration faecal indicator not designed detection specific concern (WOPHC), such as (AMR)/pathogenic bacteria, or...

10.1016/j.watres.2021.117711 article EN cc-by Water Research 2021-09-29

Understanding the role of exposure to natural recreational waters in acquisition and transmission antimicrobial resistance (AMR) is an area increasing interest. A point prevalence study was carried out island Ireland determine colonisation with extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) carbapenem-resistant (CRE) water users (WU) matched controls. total 411 adult participants (199 WU, 212 controls) submitted at least one faecal sample between September 2020 -...

10.1016/j.scitotenv.2023.164201 article EN cc-by The Science of The Total Environment 2023-05-15

Antimicrobial resistance (AMR) is one of the leading threats to human health worldwide. The identification potential sources antimicrobial resistant organisms (AROs) and their transmission routes in environment important for improving our understanding AMR inform improve policy monitoring systems, as well suitable sampling locations intervention points. This exploratory study uses geographic information systems (GIS) analyse spatial distribution likely ARO four local authority areas (LAAs)...

10.3390/antibiotics8010016 article EN cc-by Antibiotics 2019-02-27

ABSTRACT Carbapenemase-producing Enterobacterales (CPE) is a diverse group of often multidrug-resistant organisms. Surveillance and control infections are complicated due to the inter-species spread carbapenemase-encoding genes (CEGs) on mobile genetic elements (MGEs), including plasmids transposons. Due wastewater discharges, urban water ecosystems represent known reservoir CPE. However, dynamics carbapenemase-bearing MGE dissemination between in humans environmental waters poorly...

10.1128/spectrum.00904-24 article EN cc-by Microbiology Spectrum 2024-11-27

The emergence and dissemination of mobile colistin resistance (mcr) genes across the globe poses a significant threat to public health, as remains one last line treatment options for multi-drug resistant infections. Environmental samples (157 water 157 wastewater) were collected in Ireland between 2018 2020. Samples assessed presence antimicrobial bacteria using Brilliance ESBL, CRE, mSuperCARBA McConkey agar containing ciprofloxacin disc. All integrated constructed wetland influent effluent...

10.1016/j.scitotenv.2023.162649 article EN cc-by The Science of The Total Environment 2023-03-09

Understanding the role of exposure to natural recreational waters in acquisition and transmission antimicrobial resistance (AMR) is an area increasing interest. A point prevalence study was carried out island Ireland determine colonisation with extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) carbapenem-resistant (CRE) water users (WU) matched controls. total 411 adult participants (199 WU, 212 controls) submitted at least one faecal sample between September 2020 –...

10.2139/ssrn.4410817 preprint EN 2023-01-01

Abstract The emergence and dissemination of mobile colistin resistance ( mcr ) genes across the globe poses a significant threat to public health, as remains one last line treatment options for multi-drug resistant infections. Environmental samples (157 water 157 wastewater) were collected in Ireland between 2018 2020. Samples assessed presence antimicrobial bacteria using Brilliance ESBL, CRE, mSuperCARBA McConkey agar containing ciprofloxacin disc. All integrated constructed wetland...

10.1101/2022.11.03.515100 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-11-04
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