A5078197690- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Pathology Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pleural and Pulmonary Diseases
- Medical Imaging Techniques and Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Radiation Dose and Imaging
- Ultrasound in Clinical Applications
- Global Cancer Incidence and Screening
- Cardiac tumors and thrombi
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Radiology practices and education
- Tracheal and airway disorders
- Cardiac Structural Anomalies and Repair
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Trauma Management and Diagnosis
- Cardiovascular Function and Risk Factors
- Head and Neck Cancer Studies
- Aortic Disease and Treatment Approaches
- Sarcoma Diagnosis and Treatment
- Smoking Behavior and Cessation
Atrium Health Wake Forest Baptist
1998-2025
University of Arkansas for Medical Sciences
2025
Wake Forest University
2013-2023
Baptist Memorial Hospital
2015
Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences
2015
University of California, Los Angeles
2014
Brown University
2014
National Cancer Institute
2014
Mallinckrodt (United States)
2014
University of Alabama at Birmingham
2014
The National Lung Screening Trial (NLST) is a randomized multicenter study comparing low-dose helical computed tomography (CT) with chest radiography in the screening of older current and former heavy smokers for early detection lung cancer, which leading cause cancer-related death United States. Five-year survival rates approach 70% surgical resection stage IA disease; however, more than 75% individuals have incurable locally advanced or metastatic disease, latter having 5-year less 5%. It...
<h3>Importance</h3> Screening for lung cancer has the potential to reduce mortality, but in addition detecting aggressive tumors, screening will also detect indolent tumors that otherwise may not cause clinical symptoms. These overdiagnosis cases represent an important harm of because they incur additional cost, anxiety, and morbidity associated with treatment. <h3>Objective</h3> To estimate National Lung Trial (NLST). <h3>Design, Setting, Participants</h3> We used data from NLST, a...
Purpose To evaluate three coronary artery calcification (CAC) scoring methods to assess risk of heart disease (CHD) death and all-cause mortality in National Lung Screening Trial (NLST) participants across levels CAC scores. Materials Methods The NLST was approved by the institutional review board at each participating institution, informed consent obtained from all participants. Image HIPAA compliant. Five cardiothoracic radiologists evaluated 1575 low-dose computed tomographic (CT) scans...
To analyze the influence of multiple variables on rate pneumothorax and chest tube placement associated with transthoracic needle aspiration biopsy lung.In 346 patients, 331 computed tomographically (CT) guided 24 fluoroscopically lung biopsies were performed. Variables analyzed lesion size, depth, location; number pleural passes; size; presence emphysema; training level person who performed biopsy.Pneumothorax occurred at 144 (40.4%) 356 biopsies, including 139 (42.0%) CT-guided five (21%)...
The purposes of this study were: to describe chest CT findings in normal non-smoking controls and cigarette smokers with without COPD; compare the prevalence abnormalities severity evaluate concordance between visual quantitative (QCT) scoring. Methods: Volumetric inspiratory expiratory scans 294 subjects, including non-smokers, COPD, GOLD Stage I-IV were scored at a multi-reader workshop using standardized worksheet. There 58 observers (33 pulmonologists, 25 radiologists); each scan was by...
PURPOSE To provide evidence-based recommendations to practicing clinicians on radiographic imaging and biomarker surveillance strategies after definitive curative-intent therapy in patients with stage I-III non–small-cell lung cancer (NSCLC) SCLC. METHODS ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation pulmonary, radiology, primary care, advocacy experts conduct a literature search, which included systematic reviews, meta-analyses, randomized controlled trials,...
Abstract Background: Low-dose computed tomography (LDCT) screening reduces lung cancer–specific and overall mortality. We sought to assess cancer practices attitudes among primary care providers (PCPs) in the era of new LDCT guidelines. Methods: In 2013, we surveyed PCPs at an academic medical center (60% response) assessed: use, perceived effectiveness, knowledge guidelines, barriers interest education. Results: Few (n = 212) reported ordering screening: chest X-ray (21%), (12%), sputum...
Annual computed tomography (CT) is now widely recommended for lung cancer screening in the United States, although concerns remain regarding potential harms, including those from overdiagnosis.To examine effect of airflow limitation on overdiagnosis by comparing incidence, histology, and stage shift a subgroup National Lung Screening Trial (NLST).In an NLST (n = 18,714), participants were randomized to annual (CT, n 9,357) or chest radiograph monitored mean 6.1 years. After baseline...
Computed tomography (CT) screening for lung cancer has been associated with a high frequency of false positive results because the prevalence indeterminate but usually benign small pulmonary nodules. The acceptability reducing false-positive rates and diagnostic evaluations by increasing nodule size threshold screen depends on projected balance between benefits risks.
In 14 patients with biopsy-proved lymphangiomyomatosis, disease extent at computed tomography (CT) was correlated findings chest radiography and pulmonary-function testing. The CT scans radiographs were read independently by two radiologists. Disease assessed on using a visual score (0%-100% involvement of the lung parenchyma) an adaptation International Labour Office classification pneumoconioses. There good concordance between observers for radiographic scores (Kendall tau greater than or...
The appearances of the lungs on radiographs and computed tomographic (CT) scans were correlated with degree uptake gallium results pulmonary function tests (PFTs) in 27 patients sarcoidosis. CT evaluated both qualitatively quantitatively. Patients divided into five categories basis pattern abnormality at CT: 1 = normal (n 4); 2 segmental air-space disease 3 spherical (alveolar) masslike opacities 4 multiple, discrete, small nodules 6); 5 distortion parenchymal structures (fibrotic end-stage...
Importance Low-dose computed tomography (LDCT) lung screening has been shown to reduce cancer mortality. Significant incidental findings (SIFs) have widely reported in patients undergoing LDCT screening. However, the exact nature of these SIF not described. Objective To describe SIFs arm National Lung Screening Trial and classify as reportable or referring clinician (RC) using American College Radiology’s white papers on findings. Design, Setting, Participants This was a retrospective case...
Although epidemiological studies consistently show that chronic obstructive pulmonary disease is associated with an increased risk of lung cancer, debate exists as to whether there a linear relationship between the severity airflow limitation and cancer risk.We examined this in large, prospective study older heavy smokers from American College Radiology Imaging Network subcohort National Lung Screening Trial (ACRIN). Airflow was defined by prebronchodilator spirometry subgrouped according...
Localized benign fibrous tumors of the pleura.G R Ferretti, C Chiles, H Choplin and M CoulombAudio Available | Share