- Medicinal Plant Research
- Medicinal Plants and Neuroprotection
- Animal Virus Infections Studies
- Phytochemistry and biological activity of medicinal plants
- Leptospirosis research and findings
- Essential Oils and Antimicrobial Activity
- Wound Healing and Treatments
- Animal Nutrition and Physiology
- Virology and Viral Diseases
- Ethnobotanical and Medicinal Plants Studies
- Bee Products Chemical Analysis
- Microbial Metabolism and Applications
- Garlic and Onion Studies
- Biochemical and Structural Characterization
- Plant chemical constituents analysis
- Livestock and Poultry Management
- Toxin Mechanisms and Immunotoxins
- Diabetic Foot Ulcer Assessment and Management
- Parasitic Diseases Research and Treatment
- Papaya Research and Applications
- Phytochemicals and Medicinal Plants
- Neurological Disease Mechanisms and Treatments
- Education and Military Integration
- Neuroinflammation and Neurodegeneration Mechanisms
- Moringa oleifera research and applications
Universitas Wijaya Kusuma Surabaya
2018-2024
Universitas Gadjah Mada
2018-2024
Universitas Muhammadiyah Sidoarjo
2018
Universitas Muhammadiyah Jember
2018
Oranda goldfish is an ornamental fish that developed worldwide.This industry faces serious problems such as Aeromonas salmonicida infection (furunculosis).Alternative therapy required to be developed.One of them using desert rose (Adenium obesum (Forssk.)Roem.& Schult.).This study aimed elucidate the potency flower extract (DRFE) against artificially induced furunculosis in oranda goldfish.The was extracted and its quercetin content analyzed.Sixty were used a model.Fish separated into I...
The aim of this study is to explore the effect topical application Aloe vera on skin wound healing. Thirty-six male Sprague-Dawley rats weighing 150–200 grams were divided into four groups. All groups anesthetized, shaved, and exposed round full-thickness punch biopsy back: group I (control); II (treated with 1% cream); III 2% IV madecassol®). treatments given once a day. Macroscopic microscopic examination observed at 5, 10, 15 days after biopsy. Skin specimens prepared for...
Background and Aim: Antimicrobial resistance is a global problem caused by extensive utilization of antibiotics that promote gene resistant among bacteria, including Staphylococcus aureus. This study aimed to analyze the potential effects celery (Apium graveolens) extract as an antioxidant antimicrobial agent against methicillin-resistant S. aureus (MRSA), in vitro vivo. Materials Methods: Celery was extracted tested MRSA isolate vitro. The minimum inhibitory concentration (MIC) for (CE)...
The tropical area has a lot of herbal medicines such as Aloe vera (AV), Ananas comosus (AC), and Sansevieria masoniana (SM). All the three have unique potential effect an antibacterial wound-healing promoter. aim this study is to explore role AV, AC, SM on skin wound infected with methicillin-resistant Staphylococcus aureus (MRSA). Forty-five adult female Sprague Dawley rats weighing 250–300 grams were divided into 5 groups. groups exposed two round full-thickness punch biopsy MRSA. group C...
Theileriosis is a parasitic disease caused by the hemoprotozoan Theileria spp. The main transmission route of this through tick vector bite. causes economic losses in livestock such as Bali cattle. This study aims to analyze prevalence theileriosis and its correlation with hematological profile cattle from subdistrict Muara Bulian, Batang Hari, Jambi, Indonesia.Ninety-four blood samples were collected jugular vein presence was determined using smear. Routine tests double-staining...
Aflatoxin (AF) is the secondary metabolite of Aspergillus flavus and commonly contaminates feed during storage. AF causes lowered growth rate, stress, increased mortality in poultry, especially for broiler industries. The aims this study are to determine effects Sauropus androgynus (L.) Merr. leaf powder (SAP) chickens fed a diet naturally contaminated with AF. A total 108 divided into 6 group: group I basal (AF not detectable); II detectable) + 5% SAP; III (>1 ppb <50 ppb); IV ppb) V...
Aflatoxin is a worldwide problem in poultry industries as it known to contaminate feed.Aflatoxin induces stress and increases mortality rate during infection poultry, especially broiler chickens.The objectives of this study was observe the pathological effects due aflatoxicosis chickens.A total 120 chickens were divided into four groups, group A fed with basal diet without aflatoxin contamination, B (> 1 ppb < 50 ppb), C 51 100 D 101 150 ppb).The data collected analysed on day 7, 14, 21.The...
Background and Aim: One of the complications diabetes mellitus is diabetic ulcer. Diabetic ulcer commonly infected by infectious agents, especially methicillin-resistant Staphylococcus aureus (MRSA). This study aimed to evaluate potential effects alcoholic extracts Aloe vera, Apium graveolens, Sauropus androgynus on promoting wound healing in a with MRSA. Materials Methods: A total 60 male Sprague-Dawley rats (6 months old, weighing 250-300 g) were injected 65 mg/kg body weight...
The coronavirus diseases-2019 (COVID-19) pandemic has caused a global lockdown, which limited the mobility of public, and thus, more time is spent with their pets. Unfortunately, many social media have blamed pet animals as reservoir severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), etiologic agent COVID-19, triggering panic abandonment However, no article summarized information regarding role pets SARS-CoV-2 reservoirs. This study aimed to evaluate on basis research papers...
The coronavirus disease-19 (COVID-19) pandemic caused global economic and health problems. increased the number of infectious diseases categorized as neglected diseases, such staphylococcosis, which is by methicillin-resistant Staphylococcus aureus (MRSA). Celery an herb that consist antioxidants can potentially act antimicrobial agents. This study aimed to analyze efficacy celery alcoholic extract against systemic MRSA infections in rat models. In this study, 36 male, 6-month-old...
Staphylococcus aureus is a Gram-positive bacteria that influence human health.Staphylococcus becomes more serious problem if it resistant to methicillin.This phenomenon known as methicillin-resistant (MRSA).This study aimed elucidate the chemical compounds, antioxidant activity and efficacy of Aloe vera (AV), Apium graveolens (AG), Sauropus androgynus (SA) extracts its combinations against MRSA.All herbs were extracted determined constituent 2,2-diphenyl-1picrylhydrazyl (DPPH) scavenging...
Background and Aim: Newcastle disease (ND) is a viral infection that causes high mortality economic loss in the poultry industry. The Office International des Epizooties (OIE) recommends several diagnostic methods for detection of ND, including isolation molecular tests. However, these are time-consuming highly expensive. Therefore, this study was conducted to develop coagglutination kit as novel tool ND Materials Methods: Two adult male New Zealand White rabbits weighing 2.5 kg were...
Background and Aim: The massive utilization of antibiotics has increased resistant genes produced by bacteria. Many bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), have become against ampicillin (AMP). combination an herbal extract with AMP is expected to generate synergistic effects may restore the susceptibility MRSA AMP. This study aimed analyze potency Sauropus androgynous (SAE) as a single MRSA. Materials Methods: was extracted using 60% ethanol. SAE biochemical...
L eptospirosis is one of the neglected diseases distrib- uted worldwide.Leptospirosis caused by bacteria from a genus Leptospira sp.Leptospira sp. has been reported as zoonotic that can be transmitted animal to human or vice versa.Moreover, leptospirosis does not only occur in rural but also urban area.It because rodents act primary reservoir this disease (Boey et al., 2019).Rodent spread through urine environment.The presence environment promotes direct and indirect exposure leads an...
T he brain is an essential neurological system in hu- mans and animals.Brain function can be destroyed through circulatory disturbance, such as thrombus.Thrombus causes a significant decrease the blood supply that not to carry nutrition, oxygen other components tissue.Further, they promote severe stress within neuronal tissue cause death (Kuriakose Xiao, 2020).In advance, it triggers partial infarction ischemic stroke.An stroke highest prevalence humans, research
Stroke is a globally significant and devastating disease that requires prompt treatment. Animal models are commonly used to investigate stroke therapy, often through experimentally induced ischemic (EIIS). However, challenges arise in implementing EIIS animal models. The current study aimed present simple methodology for A total of 60 male Sprague-Dawley rats were randomly divided into five groups, namely Group 1 (sham-operated), Groups 2 5 (EIIS groups) with different duration common...
Ischemic stroke is commonly caused by a thrombus and its standard treatment may have side effects. Hence, the alternative therapy against ischemic requires elucidation. This study aimed to analyse efficacy of fermented calabash fruit-derived choline (Crescentia cujete L.) (FC-C) stroke. consisted four groups: CO (sham-operated group); other groups (CU, FC, PR) were artificially induced stroke, while CU (untreated); FC (2.94 mg/kg BW FC-C); PR (496 piracetam). The was applied for 14 days....
Sampah organik merupakan salah satu jenis sampah dari proses pengolahan makanan, baik selama maupun pasca produksi. yang membusuk dapat menimbulkan cemaran. Cemaran lingkungan akibat dicegah dengan atau digunakan kembali sebagai sumber pakan bagi larva (maggot) black soldier fly (Hermetia illucens, BSF). Maggot BSF mengolah berjumlah ratusan kali berat tubuhnya dan protein bahan pangan hewan. Bekas kotoran maggot (kasgot) pupuk organik. Penggunaan dalam mampu meningkatkan nilai guna sampah,...
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a formidable pathogen, causing severe infections in humans and animals, often leading to local systemic inflammation. In light of this, it becomes imperative explore novel therapeutic avenues. One such promising approach the utilization herbal-derived antioxidants, with katuk leaves (Sauropus androgynus) being prime example. This study aimed evaluate efficacy leaf extract (KLE) against MRSA infection rat models. Materials...
Background: The calabash (Crescentia cujete L.) is a tropical fruit that offers numerous health benefits. Its fermented form (FC) has been found to affect the neurological system positively. However, its impact on haematology, clinical chemistry, and CD4+ CD8+ levels yet be documented. Aim: Therefore, this study aims examine effects of FC in circulatory using rat models. Methods: This used twenty male Sprague Dawley rats. rats were divided into group 1 (0 mg/kg BW FC), 2 (50 3 (500 4 (2,000...
Background: Pasteurella multocida is an opportunistic bacterium causes pneumonic pasteurellosis (PP). The common treatment against PP using antibiotics in conjunction with nonsteroidal anti-inflammatory drugs (NSAIDs). This combination presents various complications, i.e., immune-depression. Hence, the alternative therapy to replace effects of NSAIDs needs be clarified. One them fermented calabash (Crescentia cujete (L.)) (FCC). Aim: study aimed elucidate efficacy FCC enrofloxacin...
Disease prevention in cultivating ranchu goldfish (
A female Asian palm civet (Paradoxurus hermaphroditus), three years old was carried for a medical checkup to Ruddy animal's clinic in Sidoarjo, East Java, Indonesia.The suffers enlargement of abdominal mammary glands, painless lump, asymmetric size (4.1 and 8.4 cm diameter), lacerated wound on the large one with severe haemorrhage.The unilateral mastectomy conducted under anaesthesia handles both haemorrhage tumour mass.Following surgery, mass stored 10% neutral buffer formalin...
A wound is a common problem for humans and animals. The becomes more severe if it infected by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). healing mechanism involves various factors, either in the local tissue or bloodstream. However, presentation of regarding its impacts on dynamic change blood profile not clearly understood. This study aimed to explore creation rat models with without being artificially MRSA.Thirty male Sprague-Dawley rats (6 months old; weight,...
Wound is defined as a damage of the normal anatomical structure and function tissues.Aloe verais one potential herbal on wound healing.The aim this study to explore effect topical Aloe vera skin healing in Sprague Dawley rats.Thirty six male rats 150-200 grams were divided into four groups.All groups anaesthetised, shaved, exposed two round full-thickness punch biopsy back.Group I control group; group II treated with application cream 1%; III 2%; IV madecassol®.The treatments given once day,...