- Hormonal and reproductive studies
- Cardiac Imaging and Diagnostics
- Sexual function and dysfunction studies
- Pulmonary Hypertension Research and Treatments
- Obstructive Sleep Apnea Research
- Chronic Disease Management Strategies
- Eating Disorders and Behaviors
- Cardiovascular Disease and Adiposity
- Coronary Interventions and Diagnostics
- Healthcare Systems and Public Health
- Cardiovascular Function and Risk Factors
- Neuroscience of respiration and sleep
- Climate Change and Health Impacts
- Optimism, Hope, and Well-being
- Health, psychology, and well-being
- Venous Thromboembolism Diagnosis and Management
- Nutrition and Health in Aging
- Thermoregulation and physiological responses
- Acute Myocardial Infarction Research
- Cardiovascular Health and Disease Prevention
- Health Systems, Economic Evaluations, Quality of Life
- Sleep and related disorders
- Birth, Development, and Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neurological Disorders and Treatments
Polyclinic General Hospital
2021
National Medical Research Center of Cardiology
2018-2020
National Research Institute of Public Health named after N.A. Semashko
2020
Institute of Experimental Cardiology
2012-2015
This study was carried out to evaluate polymorbidity taking into account geriatric syndromes and their relationship with the course of chronic heart failure (CHF) in outpatients aged 60 years older. Methods. We conducted an open, prospective, non-randomized study. The main group included 80 patients CHF, comparison - 40 without CHF. Conducted clinical examination, ECG, echocardiography, two-photon X-ray absorptiometry. scale assessment status CHF,Charlson comorbidity index were used....
To identify the meteorological factors or their combinations, which are most significant for development of acute coronary syndrome (ACS) in different seasons.A Statistica package was used to make an exploration analysis data A.S. Puchkov Central Emergency Medical Care Station on 63,412 admissions patients diagnosed with myocardial infarction (AMI) Moscow hospitals 2009-2012 and those Hydrometeorology Center Russia weather conditions period under study.Among patients, there were more men...
Although collateral circulation is the essential means of perfusion for ischemized myocardium, its efficiency varies substantially within and between species. There both experimental clinical evidence association glycemic disorders with inadequate col- lateral circulation. Current article reviews general mechanisms failure due to such metabolic disturbances regard stages arteriogenesis. We also highlight horizons further studies in this field.
Aim. To study the relationship between severity of erectile dysfunction and anthropometric parameters obesity in patients with arterial hypertension. Materials methods. The included 71 different dysfunction, overweight grade 1obesity were analyzed, degree characteristics assessed according to data multispiral computed tomography (MSCT), a preliminary assessment function was performed using IIEF-5 questionnaire. Later questionnaire compared in-depth urological study: collection anamnesis,...
Aim. To evaluate the prevalence of cardiovascular events and death depending on baseline coronary collateral blood flow (CBF) in five year follow-up stable heart disease (CHD) patients. Material methods. study, 579 CHD patients included, who during scheduled angiography (CAG) were diagnosed with at least one stenosis artery (diameter no less than 1,5 mm), narrowing its lumen by ≥50%. CBF was assessed Rentrop modified method. In 5 years post index CAG, counted (relapse or worsening functional...
Aim. To evaluate the association between coronary collateral circulation (CCC) and carbohydrate metabolism disorders (CMD) in patients with chronic artery disease (CAD). Materials Methods. Six hundred three CAD were included this cohort cross-sectional study. Coronary angiography images used to quantify circulation, including CCC evaluation, a modified technique proposed by Rentrop. CMD classified according WHO criteria.Potential associations evaluated using multiple linear models that...
Aim. To analyze the factors associated with a poor outcome of pulmonary thromboendarterectomy (PTE) and complications hospital postoperative period; on basis this analysis to optimize preoperative preparation therapeutic support operation. Materials methods. The study included 47 patients operable CTEPH, who underwent PTE in Department cardiovascular surgery national medical research center cardiology from 2010 2018. Patients were observed during intrahospital period, all evaluated for...
The study aims to assess the characteristics of health, psychological status, lifestyle, social and living conditions as factors affecting professional success researchers. We used content analysis literary data method expert assessments. that have a high impact on researchers include age, quality life, premature aging, cognitive load activity, emotional physical inactivity. Among average significant are job satisfaction, childbearing, educational growth, stress resistance, career work...
Aim. To evaluate the prevalence of possible obstructive respiratory disorder during sleep in outpatients by data from computed monitoring pulse oxymetry (CPO) and questionnaires. Material methods. open one stage non-randomized comparative study, 175 patients included: 37,1% males, 62,9% females, age 55,1±11,1 y.o., visiting a clinician office at outpatient facility. Sleep disordered breathing origin was diagnosed with survey, modified Stradling questionnaire CPO; excessive daytime sleepiness...
BACKGROUND : Psychological predictors of overall mortality in the Russian population Type 2 diabetic patients and their impact compared to biological risk factors have not been studied. AIM . To identify clinical, laboratory psychological independently associated with 5-year Moscow region. MATERIALS AND METHODS This open label observational prospective study included 178 consecutive type (women 145, men 33, age range 37 82 years, duration diabetes 0,5 30 years). At baseline, addition...
Aim. To assess the impact of adherence and effectiveness long-term positive airway pressure therapy (PAP-therapy) on clinical psychological characteristics patients with obstructive sleep apnea syndrome.
 Materials methods. The study included 80 who were examined in laboratory Myasnikov Institute Clinical Cardiology National Medical Research Center for have been PAP-therapy more than 12 months. average age was 65.0 years [59.0; 71.0], body mass index 35.0 kg/m2 [31.0; 38.0],...
Aim: To evaluate and compare cell-mediated immunity in patients with primary post-embolic pulmonary arterial hypertension (PAH). Methods: Flow cytometry measurement of endothelin 1, thromboxane B2 6-ketoprostaglandin F1a levels was performed 16 idiopathic PAH [iPAH] 12 [pePAH]. Results: CD3+ numbers (mature T-lymphocytes) were slightly reduced both groups (see Table), the reduction being significantly more frequent iPAH than pePAH (100% vs. 83% patients, p < 0,001). The same pattern followed...
Objective: The aim of our study was to determine the impact obstructive sleep apnea (OSA) on erectile dysfunction (ED) in patients with arterial hypertension (AH). Currently, ED is evaluated as a predictor cardiovascular diseases. Design and method: We included 71 men (mean age 47,9 ± 9,2 years) AH, receiving antihypertensive therapy (except b-blockers), OSA (according IIEF-5 questionnaire), not suffering from coronary artery disease diabetes mellitus. All underwent 21 intracavernous...
Objective: The aim of our study was to determine the interrelation between pericardial and abdominal fat (PF, AF) erectile dysfunction (ED) in patients with obstructive sleep apnea (OSA) arterial hypertension (AH). combination ED obesity OSA increases risk cardiovascular diseases their complications. Design method: We included 71 men (mean age 47,9 ± 9,2 years) AH (147,4 13,8/87,6 9,0 mm Hg), receiving antihypertensive therapy (except b-blockers), overweighted or obese (BMI 30,8 2,8 kg/m2),...
Objective: to study the relationship between erectile dysfunction and obesity parameters severity of obstructive sleep apnea in patients with arterial hypertension. Material methods : 71 different dysfunction, overweight grade 1, mild severe hypertension were included study. The data cardiorespiratory monitoring, anthropometric analyzed was assessed by intracavernous pharmacodopplerography, results compared subjective opinion on degree according IIEF-5 questionnaire. All underwent...
Abstract Background The coronary collateral circulation (CCC) varies in patients with artery disease (CAD). Although many studies were provided to detect factors associated development, genetic are still studied insufficiently. goal of this study was assess the association single nucleotide polymorphisms (SNP) genes involved vascular growth CCC stable CAD. Purpose To if variations hepatocyte factor (HGF), endothelial (VEGF), urokinase-type plasminogen activator (gene PLAU) presence...