A5017504070- Knee injuries and reconstruction techniques
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Orthopedic Surgery and Rehabilitation
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Shoulder Injury and Treatment
- Bone Tissue Engineering Materials
- Scoliosis diagnosis and treatment
- Tendon Structure and Treatment
- Medical Imaging and Analysis
- MicroRNA in disease regulation
- Pelvic and Acetabular Injuries
- Bone Metabolism and Diseases
- Surgical Sutures and Adhesives
- Dental Implant Techniques and Outcomes
- Circular RNAs in diseases
- Metal and Thin Film Mechanics
- Bone Tumor Diagnosis and Treatments
- Shoulder and Clavicle Injuries
- Oral and gingival health research
- Soft tissue tumor case studies
- Bone and Joint Diseases
- Bone health and treatments
- Hemostasis and retained surgical items
University of Hong Kong
2009-2024
University of Hong Kong - Shenzhen Hospital
2014-2024
Queen Mary Hospital
2013
Sun Yat-sen University
2007
The First Affiliated Hospital, Sun Yat-sen University
2007
Abstract Injectable hydrogel adhesives integrating both rapid adhesion to wet tissues and anti‐swelling in humid environments are highly desired for fast hemostasis wound sealing surgical applications. Herein, utilizing the synergistic effect of thermo‐sensitive shrinkable nano‐micelle gelators small molecular adhesive moieties, an injectable with rapid‐adhesion properties (RAAS hydrogel) is fabricated. The RAAS can undergo ultrafast gelation achieve within 2 s ultraviolet illumination...
Calcium phosphate cements (CPCs) have long been used as osteoconductive bone substitutes in the treatment of defects. However, degradation rate CPC is typically too slow to match new growth rate. It known that strontium increases solubility hydroxyapatite well exerts both anabolic and anticatabolic effects on bone. Therefore, we hypothesized incorporation would accelerate enhance osteoconductivity CPC. In this study, Three groups, (0% Sr-CPC), 5% Sr-CPC, 10% were prepared, with total molar...
Background: Healing of soft tissue tendon grafts within the bone tunnel in anterior cruciate ligament (ACL) reconstruction is known to be slower than that bone–patellar tendon–bone grafts. There are attempts accelerate healing graft tunnel. One methods use strontium-enriched calcium phosphate cement (Sr-CPC). Early results animal studies have been encouraging, although it not whether accelerated was solely caused by effect strontium or (CPC) itself. Hypothesis: would differences between...
Abstract Strontium (Sr) plays a special role in enhancing the biological osteo‐stimulation of calcium phosphate cement (CPC), not only increasing osteoblast‐related gene expression and alkaline phosphatase (ALP) activity mesenchymal stem cells (MSCs), but also inhibiting differentiation osteoclasts. However, incorporation Sr unfortunately delays setting CPC weakens its mechanical properties. The purpose this study was to overcome aforementioned problems by introducing chelate reaction...
To investigate the effects of miRNA-145-5p on tumor development and progression prostate cancer (Pca) bone metastasis.Levels were assessed by real-time quantitative PCR in PC3 (bone metastatic Pca cells), 22RV1 (non-metastatic RWPE-1 (non-cancerous epithelial cells) tissues collected from patients with without metastases. The impact cell proliferation was tested CCK8 assay, colony formation assay flow cytometric cycle analysis. Effects invasion migration cells determined Transwell wound...
Study Design Retrospective Case-control Study. Objectives To determine the requisite exercise compliance (EC) of physiotherapeutic scoliosis-specific (PSSE) for achieving curve regression; to analyze whether apical translation (AT), wedging (AW), and rotation (AR) major improve with regression effect. Methods Between 2019 2021, a total 763 patients undertook 6-month PSSE treatment. This resulted 426 compliable 302 uncompliable remained available analysis. For patients, 213 age-/sex-matched...
Study Design: This study adopted a prospective cohort design.Purpose: aimed to examine electromyogram (EMG) discrepancy in paravertebral muscle activity and scoliosis progression, determine how vertebral morphology EMG evolve during identify differences between individuals with without adolescent idiopathic (AIS).Overview of Literature: Higher is observed the convex side scoliotic curves, but not populations scoliosis, suggesting that higher causative factor for curve progression.Methods: In...
Abstract: Purpose: The purpose of this study was to identify the potential exosome-derived microRNAs (miRNAs) related prostate cancer (Pca) bone metastasis. Methods: Two datasets were collected. One dataset from authors' institute, for which two groups 10 patients each designed: in first one, had early-stage localised Pca without metastasis, and other, presented with Then, miRNA expression profiles blood exosomes obtained analysed. other a public transcriptome (GSE26964), downloaded Gene...
In Brief Study Design. Evaluation of a novel, leakage-free vertebroplastic instrumentation by fresh cadaveric studies. Objectives. To compare Vessel-X, novel percutaneous bone void filling container system, with conventional kyphoplasty in restoring strength, stiffness, and height experimentally induced vertebral compressive fractures morphologically determine the cement distribution. Summary Background Data. Clinically, both vertebroplasty perform well reinforcement pain relief. One...
We investigated whether strontium-enriched calcium phosphate cement (Sr-CPC)-treated soft-tissue tendon graft results in accelerated healing within the bone tunnel reconstruction of anterior cruciate ligament (ACL). A total 30 single-bundle ACL reconstructions using tendo Achillis allograft were performed 15 rabbits. The on tested limb was treated with Sr-CPC, whereas that contralateral untreated and served as a control. At timepoints three, six, nine, 12 24 weeks after surgery, three...
Injectable Anti-Swelling Adhesive Hydrogels In article number 2207741, Xiaoli Zhao, Haobo Pan, and co-workers develop an injectable anti-swelling adhesive hydrogel with rapid adhesion volume stability in humid internal environment to achieve fast hemostasis wound healing. Compared swelling bioadhesives, the this study avoids undesirable compression injury spinal cord ensures transmission of nerve signals when being applied surgery.
Objectives (1) Compare the cross-sectional thickness (CST) and shear wave speed (SWS) of paraspinal muscles (PSM) in adolescent idiopathic scoliosis (AIS) with without curve progression; (2) investigate relationship between CST/SWS radiographic characteristics AIS (3) compare non-scoliosis controls. Methods This study analyzed CST SWS PSM 48 mild to moderate curvature 24 participants. Participants greater than 45° Cobb angles were excluded. The Change within last 6-months was retrieved...
Introduction: The purpose of this study was to test whether local filling a novel strontium-containing hydroxyapatite (Sr-HA) bone cement can augment the fixation locking plate system in cadaveric proximal humeral facture model. Materials and Methods: Twelve pairs formalin-treated humeri were used. One side each pair for cemented group, while other control group. mineral density (BMD) samples tested. A 3-part model created then reduced fixed by system. In most 4 screw holes filled with 0.5...
Background: Although the popliteus muscle-tendon complex is one of most important structures in controlling posterolateral rotatory stability knee, not much literature has been reported concerning use femoral radiographic landmarks tendon repair and reconstruction. Hypothesis: By using standardized techniques, insertion could be more precisely determined by Blumensaat line than extension posterior cortex. Study Design: Descriptive laboratory study. Methods: Ten fresh-frozen human knees were...
Background Percutaneous kyphoplasty (PKP) using balloon expander has been proved to be effective in the treatment of painful vertebral compression fractures. Recently, Sky-bone expander, an alternative bone for PKP developed. The purpose this study was show our preliminary clinical outcomes with expander. Methods performed 25 patients (30 vertebrae). operation time, bleeding volume, cement volume injected were recorded. pain and functional activities before after compared Wilcoxon...
Abstract Preoperative spine flexibility plays a key role in the intraoperative treatment course of severe scoliosis. In this cohort study, we examined effects 5 day inpatient scoliosis-specific exercise (SSE) on spinal patients with adolescent idiopathic scoliosis before surgery. A total 65 were analyzed. These divided into prospective ( n = 43, age: 15 ± 1.6 years, 36 girls and 7 boys, Lenke class 1 2, Cobb angle: 64 11°) who underwent fusion 2020, retrospective 22, 1.5 17 or 63 10°),...