A5101828985- Advanced Chemical Sensor Technologies
- Reproductive tract infections research
- Gut microbiota and health
- Neurobiology and Insect Physiology Research
- Olfactory and Sensory Function Studies
- Urinary Tract Infections Management
- RNA and protein synthesis mechanisms
- RNA Research and Splicing
- RNA modifications and cancer
- Cervical Cancer and HPV Research
Florida State University
2023-2024
Firmenich (United States)
2019-2020
Firmenich (Switzerland)
2019
Albert Einstein College of Medicine
2012-2016
Yeshiva University
2012
Most natural odors are complex mixtures of volatile components, competing to bind odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) the nose. To date, surprisingly little is known about how OR antagonism shapes neuronal representations detection layer system. Here, we investigated its prevalence, degree which it disrupts ensemble activity, and conservation across phylogenetically related ORs. Calcium imaging microscopy dissociated OSNs revealed significant inhibition,...
Objective Female genital tract secretions inhibit E. coli ex vivo and the activity may prevent colonization provide a biomarker of healthy microbiome. We hypothesized that high inhibitory would be associated with Lactobacillus crispatus and/or jensenii dominant microbiome differ from women low activity. Study Design Vaginal swab cell pellets 20 samples previously obtained in cross-sectional study near-term pregnant non-pregnant were selected based on having (>90% inhibition) or (<20% anti-E....
Background The rapidly expanding field of microbiome studies offers investigators a large choice methods for each step in the process determining microorganisms sample. human cervicovaginal affects female reproductive health, susceptibility to and natural history many sexually transmitted infections, including papillomavirus (HPV). At present, long-term behavior cervical early sexual life is poorly understood. Methods V6 V6–V9 regions 16S ribosomal RNA gene were amplified from DNA isolated...
Most natural odors are complex mixtures of many volatile components, competing to bind odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) the nose. To date surprisingly little is known about how OR antagonism shapes neuronal representations periphery system. Here, we investigated its prevalence, degree which it disrupts ensemble activity, and conservation across related ORs. Calcium imaging microscopy dissociated OSNs revealed significant inhibition, often complete...
SUMMARY Most natural odors are complex mixtures of many volatile components, competing to bind odorant receptors (ORs) expressed in olfactory sensory neurons (OSNs) the nose. To date surprisingly little is known about how OR antagonism shapes neuronal representations periphery system. Here, we investigated its prevalence, degree which it disrupts ensemble activity, and conservation across related ORs. Calcium imaging microscopy dissociated OSNs revealed significant inhibition, often complete...
Human La-related protein 1 (HsLARP1) is involved in post-transcriptional regulation of certain 5' s terminal oligopyrimidine (5'TOP) mRNAs as well other and binds to both the 5'TOP motif 3'-poly(A) tail mRNAs. HsLARP1 heavily cell proliferation, cycle defects, cancer, where significantly upregulated malignant cells tissues. Like all LARPs, contains a folded RNA binding domain, La (LaM). Our current understanding that emanates from intricate molecular framework currently limited small...