- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Long-Term Effects of COVID-19
- Hemodynamic Monitoring and Therapy
- Congenital Diaphragmatic Hernia Studies
- Retinal and Optic Conditions
- Abdominal Surgery and Complications
- Abdominal Trauma and Injuries
- COVID-19 Clinical Research Studies
- Gallbladder and Bile Duct Disorders
- Antifungal resistance and susceptibility
- Neuroscience of respiration and sleep
- Non-Invasive Vital Sign Monitoring
- Abdominal vascular conditions and treatments
- Antibiotic Use and Resistance
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Bacterial Identification and Susceptibility Testing
- Surgical site infection prevention
- Intensive Care Unit Cognitive Disorders
- Dialysis and Renal Disease Management
- Pleural and Pulmonary Diseases
Hospital Clínico San Carlos
2018-2021
Hospital Clínico Universitario de Valencia
2005-2019
Hospital Universitari Germans Trias i Pujol
2018-2019
Universitat de València
2005
BACKGROUND: We investigated whether individualized positive end-expiratory pressure (PEEP) improves oxygenation, ventilation, and lung mechanics during one-lung ventilation compared with standardized PEEP. METHODS: Thirty patients undergoing thoracic surgery were randomly allocated to the study or control group. Both groups received an alveolar recruitment maneuver at beginning end of ventilation. After maneuver, group had their lungs ventilated a 5 cm·H2O PEEP, while PEEP level determined...
Anidulafungin is indicated as a first-line treatment for invasive candidiasis in critically ill patients. In the intensive care unit, sepsis main cause of acute renal failure, and with continuous replacement therapy (CRRT) has increased recent years. Antimicrobial pharmacokinetics affected by CRRT, but few studies have addressed optimal dosage anidulafungin during CRRT.We included 12 patients who received venovenous haemodiafiltration to treat failure. was infused on 3 consecutive days,...
Overall mortality in patients with acute respiratory distress syndrome is a composite endpoint because it includes death from multiple causes. In most trials, unknown whether reported deaths are due to or the underlying disease, unrelated specific intervention tested. We investigated causes of after contracting large cohort.A secondary analysis three prospective, multicenter, observational studies.A network multidisciplinary ICUs.We studied 778 moderate-to-severe treated lung-protective...
The aim of this study was to describe the etiology and outcome short-term peripheral venous catheter (PVC)-related bloodstream infections (PVCRBSI) in a 25-year period (1992 2016) identify predictive factors Gram-negative PVCRBSI. This prospective observational including all episodes
BACKGROUND: Postoperative pulmonary complications (PPCs) are common in high-risk surgical patients. ventilatory management may improve their outcome. Supplemental oxygen through a high-flow nasal cannula (HFNC) has become an alternative to classical oxygenation techniques, although the results published for postoperative patients contradictory. We examined efficacy of HFNC morbidly obese who were ventilated intraoperatively with open-lung approach (OLA).METHODS: performed open, two-arm,...
We conducted this study to test whether pulse-oximetry hemoglobin saturation (SpO2 ) can personalize the implementation of an open-lung approach during laparoscopy. Thirty patients with SpO2 ≥ 97% on room-air before anesthesia were studied. After and capnoperitoneum FIO2 was reduced 0.21. Those whose decreased below - indication shunt related atelectasis completed following phases: (1) First recruitment maneuver (RM), until reaching lung's opening pressure, defined as inspiratory pressure...
Abstract Introduction The stress index (SI), a parameter derived from the shape of pressure-time curve, can identify injurious mechanical ventilation. We tested hypothesis that adjusting tidal volume (VT) to non-injurious SI in an open lung condition avoids hypoventilation while preventing overdistension experimental model combined injury and low chest-wall compliance (Ccw). Methods Lung was induced by repeated lavages using warm saline solution, Ccw reduced controlled intra-abdominal...
Historically, the elective ventilatory flow pattern for neonates has been decelerating (DF). Decelerating waveform suggested to improve gas exchange in neonate when compared with square (SF) by improving ventilation perfusion. However, superiority of DF SF not yet demonstrated during small infants. The aim this study was compare vs. DF, or without end-inspiratory pause (EIP), terms oxygenation and an experimental model newborn piglets. lungs 12 Landrace/LargeWhite crossbred piglets were...
Miñana, A.; Ferrando, C.; Arocas, B.; Gutiérrez, Soro, M.; Belda, J. Author Information
Gutierrez, A.; García-Pérez, M. L.; Carbonell, J. Ferrando, C.; Puig, J.; Belda, F. Author Information
Hospital Clínico Universitario de Valencia, Dept of Anaesthesiology & Intensive Care, valencia, Spain
Carbonell, J. A.; García-Pérez, M. L.; Gutierrez, Gomez, Puig, J.; Belda, F. Author Information